Evaluating chatbots in psychiatry: Rasch-based insights into clinical knowledge and reasoning

Y Yu Chang (State Key Laboratory of Structural Chemistry, Fujian Provincial Key Laboratory of Materials and Techniques toward Hydrogen Energy, Fujian Institute of Research on the Structure of Matter) S Si-Sheng Huang W Wen-Yu Hsu Y Yi-Chun Liu (Department of Chemistry, James Franck Institute, and Pritzker School of Molecular Engineering)

Abstract

Chatbots are increasingly being recognized as valuable tools for clinical support in psychiatry. This study systematically evaluated the clinical knowledge and reasoning of 27 leading chatbots in psychiatry. Using 160 multiple-choice questions from the Taiwan Psychiatry Licensing Examinations and Rasch analysis, we quantified performance and qualitatively assessed reasoning processes. OpenAI’s ChatGPT-o1-preview emerged as the top performer, achieving a Rasch ability score of 2.23, significantly surpassing the passing threshold (p < 0.001). While it excelled in diagnostic and therapeutic reasoning, it also demonstrated notable limitations in factual recall, niche topics, and occasional reasoning biases. Our findings indicate that while advanced chatbots hold significant potential as clinical decision-support tools, their current limitations underscore that rigorous human oversight is indispensable for patient safety. Continuous evaluation and domain-specific training are crucial for the safe integration of these technologies into clinical practice.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 8
Published August 14, 2025
Pages e0330303
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (4)

Y

Yu Chang

State Key Laboratory of Structural Chemistry, Fujian Provincial Key Laboratory of Materials and Techniques toward Hydrogen Energy, Fujian Institute of Research on the Structure of Matter

S

Si-Sheng Huang

W

Wen-Yu Hsu

Y

Yi-Chun Liu

Department of Chemistry, James Franck Institute, and Pritzker School of Molecular Engineering