PLoS ONE
Articles in this Issue
Intergenerational instructional strategies and elderly preferences for digital applications: A Malaysian case study
Introduction As Malaysia transitions into an ageing society, older adults increasingly face challenges in acquiring digital literacy, which impacts their ability to engage with ess...
Infertility screening in unmarried women: A scoping review protocol
Objective This scoping review aims to systematically map the landscape of infertility screening in unmarried women. Introd...
Chronic kidney disease among HIV-positive Zambian adults with tenofovir-associated nephrotoxicity at University Teaching Hospital (UTH) in Lusaka
Tenofovir disoproxil fumarate (TDF) is a nucleotide reverse transcriptase inhibitor (NRTI) widely used in first-line antiretroviral therapy (ART). Despite its efficacy, TDF has been associated with ne...
The mitochondrial aspartate transporter Ucp4a regulates muscle aging and animal lifespan in Drosophila melanogaster
Mild distress of mitochondria extends animal lifespan, yet the underlying mechanisms are not completely understood. Here we screened mitochondrial proteins for effects on longevity and found that flie...
Prevalence of glaucoma in Africa: A systematic review and Bayesian meta-analysis
Purpose This study sought to establish the prevalence of glaucoma and the associated factors in Africa. Methods A systematic review of studies reporting the prevalence of glaucoma was performed usin...
Application of PSO-integrated K-means algorithm in resident digital portrait classification
As digital governance progresses rapidly, constructing digital portraits of residents has become instrumental in enhancing local-level administrative capabilities. Nonetheless, traditional K-means clu...
Early evidence for capacity standardisation in Western Europe. The vessels from Mailhac (Aude, France) 9th-7th centuries BC
This paper presents an original study of the metrological characteristics of a series of vessels discovered in the necropolis of Le Moulin (Mailhac, southern France) and dated to the Late Bronze Age a...
Drone-based application of whale tags: A “tap-and-go” approach for scientific animal-borne investigations
Deploying animal-borne suction-based tag devices on whales has been one of the primary tools used by researchers over the past several decades to gather high-resolution scientific information, such as...
Associations between neighborhood social capital, oral health risk factors, and tooth decay among Medicaid-enrolled adolescents: A hypothesis-generating preliminary study
Neighborhood-based social capital – defined as resources within neighborhood social networks – is a potential contributor to adolescent oral health, but mechanisms that link the two are not well eluci...
The impact of free trade port construction on regional import and export: Evidence from Hainan
The construction of the Hainan Free Trade Port (HFTP) represents one of the most advanced regional development models explored by China. This study clarifies the concept of the free trade port and ana...
Catalytic activity evaluation of phyto synthesized SrO and chitosan encapsulated SrO nanomaterials
Industrial wastewater contaminated with organic dyes poses significant environmental and health risks. Developing effective and eco-friendly removal methods is crucial to mitigate the harmful impact o...
Monarch butterflies (Danaus plexippus) only use magnetic cues for migratory directionality with orientation re-calibrated by coldness
Each fall, Eastern North American monarch butterflies (Danaus plexippus) leave their northern range and migrate to their overwintering sites high atop mountains in central Mexico. Although monarchs pr...
Understanding the perspectives of people with dementia and family carers about clinical pharmacists in primary care: A qualitative study
Background The number of people living with dementia is increasing, placing significant strain on healthcare systems and family carers. Primary care teams, including clinical pharmacists, are crucial...
The effect of tablet-based multimodal training on cognitive functioning in Alzheimer’s disease: A randomized controlled trial
Background Computerized cognitive training conducted in a home setting has shown beneficial effects on cognitive functions in people with mild cognitive impairment. Similar effects in people suffering...
Using safe and ethical technology to prevent and respond to sexual and interpersonal violence during adolescence and young adulthood: Identifying evidence, best practices, and pathways forward—A global scoping review protocol
Background Adolescents and young adults face elevated risks of sexual and interpersonal violence (SIV) compared to adults. Technology has been used to help mitigate this issue by mapping incidents, su...
The EuropaBON Stakeholder Dashboard: A dynamic web application to map Europe’s biodiversity community
Europe’s biodiversity faces increasing pressure from climate change, pollution, and habitat loss, while governments struggle to sustain the monitoring efforts required to respond effectively to these...
Exploring outdoor workers’ knowledge, attitudes, practices, and perceived risks of heatwaves in Nepal
Background The rise in global temperatures due to climate change has intensified the frequency and severity of heat waves, disproportionately affecting outdoor workers. This is particularly concerning...
Molecular surveillance of hepatitis E virus in wastewater in Yaoundé, Cameroon
Background Hepatitis E virus (HEV) is a zoonotic pathogen mainly transmitted through contaminated food or water in sub-Saharan countries, highlighting the need for environmental surveillance. This stu...
Study protocol of D1Ce Screen: A pilot project of the Italian national screening program for type 1 diabetes and coeliac disease in the paediatric population
Background The D1Ce Screen pilot study stems from the Italian Republic Law 130/2023 introducing the screening based on autoantibody measurement on capillary blood for the identification of people in p...
Image classification optimization technology based on differentiable neural architecture search improvement model
Image classification, as the core task of computer vision, has broad application value in fields such as medical diagnosis and intelligent transportation.However, the ability of differentiable neural...
Legume integration in smallholder farming systems for food security and resilience to climate change
A random sample of 847 households (HHs) in southern Ethiopia was used to assess the impact of HH characteristics, land and livestock ownership, seasonal variations, and agricultural challenges on cere...
Research on prostate brachytherapy puncture control strategy based on adaptive PID control with FBG sensors
This paper enhances prostate brachytherapy robot accuracy by developing a needle deflection prediction model and a controlled puncturing strategy, addressing current challenges and trends. The study a...
Novel imaging diagnosis of neuropsychiatric systemic lupus erythematosus using topological data analysis: A retrospective study
Introduction Diagnosing neuropsychiatric systemic lupus erythematosus (NPSLE) and differentiating it from systemic lupus erythematosus (SLE) without neuropsychiatric manifestations remains a substanti...
The roles of binge gaming in social, academic and mental health outcomes and gender differences: A school-based survey in Hong Kong
Binge gaming, defined as playing video games for more than five consecutive hours, has become an emerging health and behavioral issue among children and adolescents. However, the potential factors and...
Anti-obesity compounds, Semaglutide and LiPR, and PrRP do not change the proportion of human and mouse POMC+ neurons
Anti-obesity medications (AOMs) have become one of the most prescribed drugs in human medicine. While AOMs are known to impact adult neurogenesis in the hypothalamus, their effects on the functional m...