PLoS ONE
Articles in this Issue
Steel surface defect segmentation with SME-DeeplabV3+
Accurate segmentation of steel surface defects is crucial for ensuring steel quality. This paper presents a steel surface defect segmentation method based on SME-DeepLabV3+ to improve the accuracy and...
Analysis of adverse drug reactions in 507 cases of Tislelizumab: A real-world retrospective study based on data from Guangxi, China
Objective To analyze the real-world characteristics and patterns of adverse drug reactions (ADRs) associated with tislelizumab, providing valuable insights for clinical practice. Methods We conducte...
Cannabidiol improves learning and memory deficits and alleviates anxiety in 12-month-old SAMP8 mice
Cannabidiol (CBD) has gained a lot of interest in recent years for its purported medicinal properties. CBD has been investigated for the treatment of anxiety, depression, epilepsy, neuroinflammation,...
Numerical simulation and field experiment study of the supersonic gas jet subsoiler based on DEM
To tackle the challenges of high draft resistance, limited subsoiling range, and ineffective subsoiling results in conventional subsoiling methods, this study combines the structure of an air cannon w...
Flow similarity model predicts allometric relationships among Acer platanoides L. branches
Using physical models to predict patterns of plant growth has been a long-standing goal for biologists. Most approaches invoke either thermodynamic, biomechanical or hydraulic principles and assume th...
Activated human B cells produce phospholipase D4-containing extracellular vesicles
Phospholipase D4 (PLD4) is an intracellular exonuclease implicated in immune regulation via nucleic acid degradation. While public proteomic databases indicate the presence of PLD4 in human plasma, it...
Spatial patterns and predictors of antenatal care interruption in war-torn Tigray, northern Ethiopia: Spatial modelling approach
Introduction Antenatal care (ANC) is vital for maternal health, yet its provision has been severely disrupted in conflict-affected Tigray, Ethiopia. This study employs a community-based approach to an...
RPIPLM: Prediction of ncRNA-protein interaction by post-training a dual-tower pretrained biological model with supervised contrastive learning
The field of biological research has been profoundly impacted by the emergence of biological pre-trained models, which have resulted in remarkable advancements in life sciences and medicine. However,...
The current status and determinants of perceived ageism among community-dwelling older adults: A cross-sectional, multifactorial analysis
Objective To investigate the prevalence of perceived ageism among community-dwelling older adults and systematically analyze its determinants, thereby providing a reference for the management of menta...
Superoxide dismutase VPA1514 in Vibrio parahaemolyticus protects against environmental stresses
Vibrio parahaemolyticus is a foodborne enteropathogen that has become a global concern since the emergence of the pandemic O3:K6 strain in 1996. Three putative superoxide dismutase...
Immune cells play a critical role in cytokine- and endotoxin-mediated endothelial permeability
Vascular leakage (VL) is a severe pathology occurring in a broad range of scenarios, e.g., during sepsis, cytokine storms, or as side effect of immunotherapies. Its severity is underlined by the high...
Silent voices: Uncovering women’s absence in veterinary surgery publications
Objective To determine the factors associated with an author being female in Veterinary Surgery journal publications from 2002 to 2023....
Management of acute appendicitis in pregnancy (MAMA): Protocol for a multicentre observational study
Introduction Acute appendicitis is the most common emergency general surgical condition in pregnancy, affecting around 1 in 1000 pregnancies. Reaching a diagnosis is more challenging in this group bec...
Thematic morning report in clinical training for critical care medicine resident physicians: Preliminary exploration in a tertiary hospital of China
Morning report (MR) is one of the most important forms of resident standardized training. However, at present, it has not been carried out in most residential training bases in China. The specific con...
Effect and validation of plate thickness dimensional effects on grouting compactness in bridge ducts based on ultrasonic testing
Based on the theory of ultrasonic non-destructive testing, this study investigates the dimensional effect of plate thickness on the detection of grouting compactness in prestressed bridge ducts. By co...
National health insurance membership in Indonesia: Do socio-economic elements matter?
The Indonesian government released a National Health Insurance (NHI) policy to realize universal health coverage (UHC) in Indonesia, yet disparities in membership persist. The study examined the influ...
Decoding budget awareness: A multivariate analysis of generation Z undergraduates
Understanding public finance and budget processes has become increasingly important for the younger generation in recent years. This knowledge enables Generation Z to participate more effectively in d...
Predicting achievement of clinical goals using machine learning in myasthenia gravis
Background Myasthenia Gravis (MG) is an autoimmune disease characterized by the production of autoantibodies against neuromuscular junctions, leading to varying degrees of severity...
Alteration of BDNF and noradrenergic markers in locus coeruleus in a mouse model of cancer-induced bone pain
The locus coeruleus (LC) is the principal source of noradrenaline (NA) in the central nervous system. In neuropathic pain states, nociceptive stimuli activate LC. This study examined the expression an...
Peer play network in preschool classrooms: Features and variations by child characteristics and skills
Peers play a critical role in creating opportunities for learning. However, less is known about how children form peer play networks in preschool and how their level of connection in peer play varies...
Transition of milk fatty acid profile and vitamins A and E from colostrum to mature milk in Danish Holstein cows
Colostrum, the initial milk produced by mammals after giving birth, has evolved to serve as a primary rich source of essential nutrients for newborns. However, there are considerable changes in nutrie...
Exploring the addictive processes in repetitive self-harm through a grounded theory approach: “It always felt like a choice until it didn’t”
Introduction There is limited empirical research to suggest repetitive self-harm can be understood or conceptualised as an addictive behaviour. However, few empirical studies have...
Longitudinal progression of cost-related medication non-adherence among Medicare patients with diabetes at high risk of hospitalization: The role of dual eligibility
Objective Little is known about the longitudinal progression of cost-related medication non-adherence (CRN) among the high-need, high-cost diabetes population. We aim to document t...
Validation of the Multidimensional Sociosexual Orientation Inventory (SOI-M) in the Chilean population
We used the SOI-M Multidimensional Sociosexual Orientation Inventory developed by Jackson and Kirkpatrick for validation in the Chilean population. This 3-dimensional instrument measures sociosexualit...
Colorimetry characteristics and color clustering of natural gem-quality spinel from Myanmar (Burma)
Color is the most critical factor in determining the value of gem-quality spinel. This paper examines the color mechanism and the colorimetric characteristics of spinel crystals under D65 and A light...