PLoS ONE
Articles in this Issue
Characteristics and genesis of permian chert in the middle and upper Yangtze Region, China
Cherts, as chemical sedimentary formations, serve as repositories of historical evolutionary data encompassing paleotectonics, paleogeography, and paleoclimate. Furthermore, they play a crucial role a...
Correction: Reasons for stopping Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC): A retrospective study to improve future patient selection
High throughput machine learning pipeline to characterize larval zebrafish motor behavior
Using machine learning, we developed models that rigorously detect and classify larval zebrafish spontaneous and stimulus-evoked behaviors in various well plate formats. Zebrafish are an ideal model s...
Factors that influence an individual’s decision to undergo bariatric surgery: A qualitative systematic review
Introduction Obesity is a significant health issue associated with chronic conditions such as cardiovascular disease and type 2 diabetes. Bariatric surgery is the most effective weight loss treatment...
A mathematical study for psoriasis transmission with immune-mediated time delays and optimal control strategies
In psoriasis, dendritic cells activate T cells, which then release excessive pro-inflammatory cytokines, leading to abnormal growth of keratinocytes in the epidermis. At the same time, anti-inflammato...
Fear of childbirth in primipara women and its correlation with premenstrual syndrome: A cross-sectional study
Introduction Fear of Childbirth (FOC) is the most common psychological problem among pregnant women, especially in primipara women who are more likely to fear the unknown delivery...
Investigating the HIV epidemic among Black gay and bisexual men in the Southern United States: Results of the HPTN 096 pilot cross-sectional assessment
Background The HIV Prevention Trials Network (HPTN) 096 study was designed to address the markedly higher rates of HIV incidence among Black men who have sex with men (MSM) in the...
Achieving consistency in FedSAM using local adaptive distillation on sports image classification
Federated learning (FL) is an effective distributed learning paradigm for protecting client privacy, enabling multiple clients to collaboratively train a global model without uploading private data. I...
Prevalence of overweight and its associated factors among selected higher secondary schools adolescents of Kathmandu Metropolitan City, Nepal
Overweight is highly prevalent in lower- and middle-income countries (LMICs), including Nepal. Due to the rapid physical and mental growth among adolescents, they are nutritionally vulnerable and sens...
Public discourses of alternative protein foods in Facebook public pages’ posts, 2014–2024
“Alternative protein” (AP) refers to protein sources that are different from conventional animal-based proteins. This category encompasses a variety of highly processed plant-based proteins, cultured...
Real-world pharmacovigilance of risperidone: Analysis based on FAERS reports from physicians and pharmacists
Objective Risperidone, a second-generation antipsychotic widely used in clinical practice, has not been systematically evaluated for its long-term real-world adverse events. This study analyzed risper...
Nonlinear control of a fully actuated robotic hand using high-order sliding mode and feedback linearization controllers
The increasing adoption of prosthetic devices in medical applications introduces complex and variable load conditions, particularly due to the diverse nature of user disabilities. To address the resul...
FoxO3a regulated by miR-150-5p promotes the pyroptosis of macrophages in atherosclerosis
Background This study uses tissue exosome analysis to explore the role of miR-150-5p and its downstream genes in atherosclerosis (AS), an area where the functional mechanisms and pathophysiological si...
Impact of substrate choice on human osteoclast differentiation and secretome: Implications for targeted therapeutic development
Osteoclasts (OCs) exhibit substrate-specific molecular adaptations crucial for bone remodeling. We utilized mass spectrometry and functional enrichment analysis to delineate the proteomic profiles of...
The interplay between social dominance and decision-making under expected and unexpected uncertainty: Evidence from event-related potentials
Decision-making is a fundamental aspect of human behavior, especially in uncertain situations where social interactions play a significant role. Social dominance, which involves power dynamics within...
The antibacterial effect of human adipose-derived stem cells on LL-37-resistant bacteria
Human adipose-derived stem cells (hADSCs) exhibit antibacterial properties, but their effectiveness against bacteria resistant to LL-37- a natural human antimicrobial peptide important in the immune d...
A new functional classification of U.S. metropolitan and micropolitan areas
This study develops a new functional classification of metropolitan and micropolitan areas in the United States. The methodology used was based on the widely used locational quotient and the Coefficie...
Spatial factors affecting young females’ disaster exposure in municipalities facing population decline
Understanding and reducing the risk of natural disasters is crucial for maintaining the economy and society. Since Japan is a disaster-prone country and the most advanced nation in the world regarding...
Reasons for consultations and afflicted body systems in rural areas of The Republic of the Congo: A cross-sectional study
In the Republic of the Congo, rural areas are characterized by vulnerable populations and endemic infectious diseases, while health facilities have limited technical capabilities. Our objective was to...
How migrants’ transcultural perceptions shape their children’s bilingual language development: Insights from a cross-sectional multicultural study
Background Little is known about the factors affecting children’s language acquisition in transcultural situations and how clinicians can take these children’s specific needs into account. Objective...
Higher anaerobic digester performance by the strategical increase in the feeding rate of cow manure in laboratory continuous stirred tank reactor
Improper management of dairy cow manure poses a major risk of environmental pollution. In contrast, anaerobic digestion provides a sustainable pathway by transforming manure into renewable biogas whil...
A multicriteria model for prioritizing 5G network deployment with Monte Carlo stability analysis: A case study in Magdalena, Colombia
The global deployment of 5G mobile networks has followed a progressive and strategic approach, depending on regional characteristics. This study develops a reference framework to prioritize areas for...
Occupational exposure to polycyclic aromatic hydrocarbons and cognitive impairment: Protocol of a systematic review
Occupational exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with adverse health effects, yet evidence on the cognitive consequences of such exposure remains fragmented and has...
Transfer learning-driven prediction of oil and gaspipeline corrosion rates in small sample scenarios
To ensure the safe operation of oil and gas pipeline systems in complex environments, accurately predicting the corrosion rate of natural gas well pipes is of paramount importance. Given the widesprea...
SARS-CoV-2 sequencing artifacts associated with targeted PCR enrichment and read mapping
Protocols and pipelines for SARS-CoV-2 genome sequencing were rapidly established when the COVID-19 outbreak was declared a pandemic. The most widely used approach for sequencing SARS-CoV-2 includes t...