PLoS ONE
Articles in this Issue
A study on identifying the phenotypic saturation thresholds of broomcorn millet based on functional limits and growth models
Broomcorn millet, renowned for its strong stress tolerance and rich nutritional value, serves as a crucial germplasm resource in the arid and semi-arid regions of northern China. It exhibits advantage...
“You have to walk on eggshells around him”: Female partners’ perspectives on the opportunities and challenges of dealing with a male partner’s depression—A qualitative study
Purpose Partners of people with mental illness can play an important role in helping them cope with the illness. Previous studies have highlighted the potential burden of depressio...
SARS-CoV-2 spike protein causes synaptic dysfunction and p-tau and α-synuclein aggregation leading cognitive impairment: The protective role of metformin
Patients recovering from post-coronavirus disease 2019 (COVID-19) often experience cognitive dysfunction, including difficulties with focusing, conversation, or memory issues, which can persist for we...
Living with a loved one’s mental health issue: Recognizing the Lived Experiences of Military Spouses
Limited evidence surrounds the lived experiences of military spouses whose partner has mental health issues. This lack of evidence may be due to factors such as global austerity, underfunding of armed...
Fading connections: A phenomenological study of oncology nurses’ experiences of Missed Nursing Care during an infectious disease outbreak
Purpose Providing holistic and high-quality nursing care to oncology patients necessitates integrating care across physical, psychological, spiritual, and emotional domains. This s...
Exploring proxies for occupation intensity in hunter-gatherer settlement systems: A combination of ethnohistoric and archaeological data
A primary concern for hunter-gatherer archaeology is whether occupation intensity can be broken down into its constituent components: group size, length of stay(s), and frequency of reoccupation. This...
Evaluating Amazon effects and the limited impact of COVID-19 with purchases crowdsourced from US consumers
We leverage a recently published dataset of Amazon purchase histories, crowdsourced from thousands of US consumers, to study changes in online purchasing behaviors over time, how changes vary by demog...
Co-generation of NaREE(MoO4)2 and REEPO4 in multiple habits by solid-flux crystal growth
Rare Earth Elements (REE) are key to modern technology and industrial processes. They are most used in electronics, although their chemistry enables numerous other applications. Oxides that combine RE...
Structural and evolutionary constraints shape adaptive landscapes of immune-related genes across mammalian phylogeny
The evolutionary dynamics of immune-related genes GBP5, GZMB, IFNG, IRF7, KLRD1, RTP4, TNFSF4, and TRAT1 were investigated through comprehensive phylogenetic and selection analyses across mammalian sp...
Honey bees of Ethiopia: Their lineages and subspecies based on morphometrics, mitochondrial DNA, and mandibular gland pheromone analyses
Apiculture is a vital economic sector in Ethiopia, providing income and employment for over two million people. However, the classification of the honey bee subspecies in Ethiopia remains debatable. T...
Knowledge transfer-driven estimation of knee moments and ground reaction forces from smartphone videos via temporal-spatial modeling of augmented joint kinematics
The knee adduction and flexion moment provides critical information about knee joint health, while 3D ground reaction forces (GRFs) help identify force and energy characteristics for maneuvering the e...
Efficient DNA extraction from cytogenetic suspensions: A new possibility for obtaining DNA, with potential applications in studies of molecular markers
The present study demonstrates the viability of extracting DNA for genomic analyses from cell suspensions prepared for cytogenetic analyses, specifically, samples fixed in Carnoy’s solution (3:1 metha...
Multi-omics analysis reveals metabolic regulation of phosphatidylcholine, triglycerides, phosphatidylethanolamine, and cardiolipin metabolism in mouse liver with metabolic dysfunction-associated steatotic liver disease
The dysregulation of phosphatidylcholine (PC), triglycerides (TG), phosphatidylethanolamine (PE), and cardiolipin (CL) metabolism is believed to contribute to the development of MASLD. However, little...
Joint predictors of antenatal care contacts and timing of antenatal care initiation among women of reproductive age in Ethiopia
Background Maternal and neonatal mortality remain major public health challenges, particularly in low-income countries like Ethiopia. Antenatal care (ANC) pl...
A systematic comparison of patient information leaflets from local and multinational pharmaceutical companies: Assessing content quality and completeness
Background It is necessary to provide essential information to patients regarding medication to ensure safe and effective use. Patient Information Leaflets (PILs) are vital to fulf...
Morphological and histological features of abdominal glands in Japanese marten (Martes melampus)
The Japanese marten ( Martes melampus ) is a solitary mustelid species with a strict territorial space that might be maintained by scent marking. However, wheth...
Study on automatic lithology identification method while drilling based on acoustic pressure-rock physics parameters mapping
The lithology identification while drilling is a critical component of intelligent coal mine exploration. Investigating automatic lithology identification methods is of great significance for enhancin...
Correction: Boosting or inhibiting - how semantic-pragmatic and syntactic cues affect prosodic prominence relations in German
Global trends in the proportion of macrolide-resistant Mycobacterium Species: A systematic review and meta-analysis
Background Macrolide resistance in Mycobacterium species is an emerging global problem, complicating treating non...
Orthotropic reconstruction and characterization of bone tissues through a visco-plasto-damage model
This study presents a robust numerical framework for modeling bone tissue mechanics, integrating an orthotropic visco-plasto-damage model with high-resolution bone geometries derived from computed tom...
Optimizing the in vitro production of immunomodulatory cells for the induction of tolerance in solid organ transplantation
Background Cell therapy can be utilized to induce operational tolerance following solid organ transplantation. In thi study, donor-specific immunomodulatory cells (DSIMC) are gener...
Exploration of key markers driving ferroptosis in the progression of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a prevalent condition strongly linked to obesity, diabetes, and metabolic syndrome. Its global incidence is steadily increasing, placing a significant heal...
Can data assetization drive high-quality enterprise development?—Evidence from China’s “Specialized, refined, unique, and innovative” SMEs
Data assetization empowers the high-quality development of “Specialized, Refined, Distinctive, and Innovative” (SRDI) small and medium-sized enterprises (SMEs) by enhancing organizational performance...
Development and Validation of a Tobacco Testing Laboratories Assessment Tool
Background Effective regulation and control of tobacco products require robust laboratory testing capabilities to ensure quality, safety and compliance with relevant standards. Cur...
Adverse childhood experiences and COVID-19 vaccination uptake: Examining the intersection of sex and urban-rural residence
Background Adverse childhood experiences (ACEs) have been linked to negative health outcomes and behaviors in adulthood. Despite widespread research on ACEs, their relationship wit...