PLoS ONE
Articles in this Issue
Disambiguating sentiment annotation: A mixed methods investigation of annotator experience and impact of instructions on annotator agreement
Human-annotated datasets are central to the development and evaluation of sentiment analysis and other natural language processing systems. However, many existing datasets suffer from low annotator ag...
Association between the atherogenic index of plasma and the occurrence of acute kidney injury in critically ill patients with sepsis: A retrospective study
Background The atherogenic index of plasma (AIP) is a recognized marker of atherosclerosis and cardiovascular disease (CVD). However, the association between AIP and the risk of ac...
A data-driven analysis of patient selection for xenotransplant human clinical trials
The demand for transplant organs far exceeds the available supply. In the United States alone, more than 90,000 patients are currently on the kidney transplant waitlist, yet only about one third of th...
Precarious employment and gender-based violence against migrant women: A scoping review mapping the intersections
The risk of gender-based violence (GBV) against migrant women is largely exacerbated by precarious employment opportunities available to them as they go through the resettlement process. Despite the r...
Evolution of talent policies in Guangdong-Hong Kong-Macao greater bay area: An LDA thematic model approach
As construction of the Guangdong-Hong Kong-Macao Greater Bay Area advances, talent has become the core driving force for its development. This study quantitatively analyzes 94 talent policies from Gua...
Development of a low-cost culture medium from industrial and environmental by-products for sustainable cultivation of Lactic Acid Bacteria
Conventional culture media such as de Man, Rogosa and Sharpe are essential for the growth of lactic acid bacteria and the production of metabolites used in the food and pharmaceutical industries. Howe...
Factors associated with phylogenetic clustering of hepatitis C virus, mainly among people who inject drugs who access HIV prevention services in South Africa, 2016–2017
People who inject drugs (PWID) are disproportionately burdened with hepatitis C virus (HCV) infection in South Africa (SA). Transmission dynamics can be inferred using phylogenetic clustering to infor...
Drivers and determinants of extreme humanitarian needs among Rohingya refugee households: Evidence from UNHCR’s multi-sectoral needs analysis
Background The Rohingya refugee crisis continues to deteriorate amid major funding cuts and a myriad of intensifying threats. Approximately one million Rohingya refugees are curren...
Dysregulated serum chloride and clinical outcomes in critically ill adults: A systematic review and meta-analysis
Dysregulated serum chloride levels are prevalent in critically ill patients. However, their clinical impact remains unclear. This first systematic review and meta-analysis quantified the prevalence of...
A reliable in vitro rumen culture system and workflow for screening anti-methanogenic compounds
Arguably the biggest man-made challenge of the century is halting climate change. Livestock’s methane (CH 4 ) emissions, a greenhouse gas with a higher global w...
A mathematical model of HCV transmission dynamics with sex stratification and environmental effects
This study primarily aims to determine how sex-specific behaviors influence Hepatitis C Virus (HCV) transmission dynamics among people who inject drugs (PWID), and to identify key parameters and inter...
Testing for the footprints of stabilization economic policy in forecast errors
This paper introduces a novel statistical test, the Policy Effects Lagrange Multiplier (PELM) test, to detect stabilization policy effects in the distribution of forecast errors from dynamic financial...
What do we actually know about the biomechanics of pregnancy and labour? A systematic scoping review
Pregnancy and childbirth involve profound biomechanical transformations, adaptations, and functional demands on the maternal body. Although biomechanical complications have been identified as a major...
Prevalence and genotype distribution of Human Papillomavirus (HPV) among 14,110 women in Anqing urban area: A population-based cross-sectional survey
Human papillomavirus (HPV), particularly persistent infection with high-risk types, is one of the major etiological factors for cervical cancer, posing significan health risks to women. This study aim...
Correction: Spatial heterogeneity of microbial community structure and its environmental drivers in surface sediments of Erhai Lake
Global prevalence of E-cigarette use among students: Systematic review and meta-analysis
Background The growing use of e-cigarettes among students is a major public health concern. Yet, global data on its prevalence and associated risk factors remain limited. Therefore...
Investigating the mechanism of oridonin against triple-negative breast cancer based on network pharmacology and molecular docking
Oridonin, a tetracyclic diterpenoid from Rabdosia rubescens (Hemsl.) Hara, exhibits various pharmacological actions, such as anti-tumor, anti-infective, and ant...
Annual U.S. healthcare expenditures attributable to cigar smoking between 2001 and 2018, overall and by payer
Background In 2022, 3.7% of U.S. adults currently smoked cigars. This study assesses cigar-smoking-attributable fractions in U.S. healthcare expenditures and associated annual heal...
eDNA reveals spatial differences in species composition of protected rockfishes
Rare species are difficult and time-consuming to detect, but environmental DNA (eDNA) methods can be used to increase data availability for monitoring and management. Here, we use the diverse rockfish...
Rapid, without focus stacking, 3D photogrammetric digitization of cockroaches
Natural history collections are seen as treasure troves we need to both preserve and study. Campaigns of 2D and 3D digitization have emerged in numerous institutions as an opportunity to maximize spec...
Design and implementation of a graphene–polyimide-based H-slot terahertz antenna for wireless and biomedical applications
THz antennas, which function at high speeds, frequencies, and data rates, were developed in response to the increased need for high-speed communication equipment. In this work, a MIMO antenna operatin...
The EQo-Mental project: A protocol for a mixed-methods study on occupational balance and mental health in parents of children with developmental delays
Background Parents of children with developmental delays (DD) often face significant challenges that affect their mental health and occupational balance. While early intervention s...
Assessing PFAS exposure in Rocky Mountain elk (Cervus canadensis nelsoni) populations adjacent to the former Rocky Flats nuclear site: A preliminary analysis
The Rocky Flats National Wildlife Refuge is located west of Denver, Colorado, USA along the central Front Range of the Rocky Mountains. The wildlife refuge property includes a former U.S. Department o...
Multivariate analysis of Iris meda Stapf based on phenological and morphological characteristics
The genus Iris represents one of the most diverse and horticulturally valuable ornamental groups worldwide, with considerable ecological, morphological, and gen...
DNA N6-methyladenine modifications of Acidithiobacillus ferrooxidans response to copper stress
High concentrations of copper ions have long been recognized as a key factor limiting the efficiency of bioleaching due to the metal toxicity to microorganisms. In order to identify new determinants o...