PLoS ONE
Articles in this Issue
The relationship between sleep disorders and postoperative delirium in adult patients: Protocol for an updated systematic review and meta-analysis
Introduction Postoperative delirium (POD) is a common complication after surgery. The association between sleep disorders and the risk of POD has been widely studied. Sleep disorde...
Is low birth weight associated with lower adiponectin levels? - A systematic review and meta-analysis
Individuals born with low birth weight are at increased risk of type 2 diabetes, which potentially may be attributed to immature adipose tissue development and reduced levels of the insulin-sensitizin...
Age-dependent patterns of cardiac complexity unveiled by topological data analysis of pediatric heart rate variability
Heart rate variability (HRV) is a well-established marker of autonomic regulation and undergoes profound maturation during early human development. In this study, topological data analysis (TDA) is ap...
Unhealthy food consumption among 20–59 years old adults in Bangladesh: Findings from a nationally representative cross-sectional survey
Background Unhealthy food consumption is a major public health concern because of its adverse health consequences. We assessed unhealthy food (savory and fried snacks, SFS; sweet s...
Erosive potential of energy drink modified by calcium formulations on dental enamel: An in vitro study
Objectives To evaluate the erosive potential of an energy drink modified with different calcium formulations and concentrations on dental enamel....
Retraction: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive systematic review and meta-analysis
ceRNA regulatory network and immune-neurodegenerative mechanisms of peripheral CD4+ T cells in parkinson’s disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neuron loss and neuroinflammation, with emerging roles of peripheral immune dysregulation in disease progression....
Factors Influencing SurgeCon Implementation in Four Canadian Emergency Departments Guided by Consolidated Framework for Implementation Research
Background Emergency department (ED) overcrowding remains a significant national issue in Canada. To address this issue, SurgeCon, a quality improvement program, was implemented to...
Role of thyroid autoimmunity independent of thyroid hormone levels in pulmonary function decline: A population-based study in euthyroid adults
Purpose Although overt thyroid dysfunction has been associated with changes in pulmonary function, the effects of thyroid hormone levels and thyroid autoimmunity on lung function i...
Cultivating competitive advantage for Chinese SMEs via big data analytics: The mediating role of data-driven innovation and antecedents of data governance and data-driven culture
This study explores how small and medium-sized enterprises (SMEs) can leverage big data analytics (BDA) to gain competitive advantage (CA), highlighting the mediating role of data-driven innovation (D...
Development of basic-needs experience and finance-related attitude through game-based learning: The role of game mechanics and debriefing
Game-based learning (GBL) supports the development of domain-specific competencies, especially knowledge, more effectively than traditional learning methods. However, it is still unclear which element...
Predicting future forest fire occurrence probability based on drought characteristics at various temporal scales in P. R. China
Future climate change will lead to extreme weather events, such as droughts, which may exacerbate forest fire regimes. However, the impact of future drought characteristics on forest fire regimes has...
The BrainWaves study of adolescent wellbeing and mental health: Methods development and pilot data
Adolescent mental health and wellbeing are of growing concern globally with increased incidence of mental health disorders in young people. BrainWaves provides a framework for relevant and diverse res...
Network pharmacology reveals Ficus. Carica. L latex as a potential therapeutic agent for gastric ulcers by modulating inflammation and promoting repair
The primary objective of our research is to investigate the gastroprotective impact of Ficus. carica L. latex extract (FCL). Metabolic profiling based on HR- LC...
A qualitative study of abortion professionals’ perspectives on doula support
Objective(s) Doulas provide non-clinical support to people in pregnancy, labour and delivery, and, increasingly, to abortion-seekers. Even in contexts of decriminalization and proa...
Modifiable risk factors for inflammatory bowel disease in Kuwait: A cross-sectional analysis
Inflammatory bowel disease (IBD), a lifelong inflammatory condition of the gastrointestinal tract, is influenced by complex interactions between genetics and environmental exposures. While IBD rates h...
An explanatory sequential mixed method study of nursing students’ self-efficacy in caring for older adults in Ghana
Background There is considerable evidence indicating that nursing students demonstrate inadequate knowledge and negative attitudes toward working with older adults. This suggests n...
Comparison between Legiolert and real time PCR in the detection of Legionella pneumophila from environmental water samples
Legionellosis is a resvpiratory disease of public health concern. Identification and quantification from environmental sources are crucial for identifying outbreak origins and providing information fo...
Association between the neutrophil percentage-to-albumin ratio and pelvic adhesion severity in endometriosis: A retrospective cross-sectional study
Study background Preoperative assessment of the severity of pelvic adhesions in endometriosis remains challenging. Inflammation may drive adhesion formation, and the predictive val...
PROMPTa—A multifaceted assessment approach to develop writing skills
Assessment plays a pivotal role in developing writing skills, yet traditional teacher-led evaluations often fall short in addressing learner’s diverse needs, creating a substantial gap in effective wr...
The epidemiology and management of chronic osteomyelitis in pediatrics – A systematic review
Objectives Infection leading to necrosis of any bone can lead to chronic osteomyelitis (CO), sometimes resulting in permanent orthopedic sequelae. There are no published guidelines...
Effect of charging conditions on the storage performance of a conformable adsorbed natural gas tank packed with HKUST-1
Adsorbed natural gas (ANG) technology represents a viable option for energy storage solutions. However, the enhancement of the storage performance is constrained by the thermal effect inherent to conf...
Perceived clinical and ethical impact of digital transformation in healthcare and research: A survey in the MENA region
Background The shift toward digital medical records and communication represents a transformative change in healthcare practices and research. However, this transition is marked by...
Stillbirth in twin pregnancies in Stockholm County 2000–2021—A descriptive study
Introduction The incidence of stillbirth is higher in twin pregnancies compared with singleton pregnancies. Known risk factors for stillbirth in twin pregnancies include selective...
Development and validation of a simple, cost-effective competitive allele-specific PCR assay for largescale screening and detection of FecB mutation in sheep
The Booroola fecundity (Fec B ) gene, a mutation in the bone morphogenetic protein receptor-1B (BMPR1B), is known to increase ovulation rate and litter size in...