PLoS ONE
Articles in this Issue
Barriers and facilitators for self-harm prevention and surveillance: A cross-sectional study with primary health care nurses in Brazil
Most individuals who die by suicide do not have contact with specialised mental health services; instead, they engage with primary health care services. This highlights the critical role of primary ca...
Prehypertension and its associated factors among government employees in Tilottama Municipality of Rupandehi District, Nepal
Government employees are vital workforce of the nation comprising individuals in the working age group. These employees have to face an increased workload, limited decision-making scope, lack of suppo...
DynamicSeq2SeqXGB for PM2.5 imputation in extremely sparse environmental monitoring networks
Environmental monitoring networks face critical data gaps that compromise public health protection and regulatory compliance, with missing data rates often exceeding 40% in operational settings. This...
Corollary discharge and efference copy mechanisms in schizophrenia and controls: The N1 and P2 evoked potential components differentially react to self-initiated tones in schizophrenia
“Efference copy” and “corollary discharge” mechanisms may help to distinguish internal from external stimuli. Previous studies indicate that patients with schizophrenia show a lack of N1 evoked respon...
Effects of supplementing hemp (Cannabis sativa L.) leaves in concentrate diet on carcass traits and meat characteristics of Longissimus muscle in goat kids
The influence of dietary hemp ( Cannabis sativa L.) leaf (HL) supplementation in a concentrate diet on carcass traits, physicochemical properties, amino acids,...
Generation of a primary culture of chick embryo enterocytes to evaluate the effects of fumonisin B1 and deoxynivalenol on cell morphology, actin filaments and nuclei
Fumonisin B1 (FB1) and deoxynivalenol (DON) are among the most impactful mycotoxins affecting poultry production. The negative effects of these mycotoxins on intestinal epithelial morphology and integ...
Transport of CCL2 across an induced pluripotent stem cell-derived in vitro model of the human blood-brain barrier is heparan sulfate-dependent
Transport of immune-active substances across the blood-brain barrier (BBB) is an important mechanism of neuroimmune regulation. CCL2 is an exemplary chemokine that regulates neuroinflammation and can...
The effects of high-frequency repetitive transcranial magnetic stimulation on negative symptoms in schizophrenia patients: A systemic review and meta-analysis
Objective The research on high-frequency repetitive transcranial magnetic stimulation (rTMS) is very ambiguous, particularly the variability in treatment parameters and the need fo...
Clear tracks or missed connections? A qualitative study exploring how interest-holder perceptions of purpose shape the implementation and experience of the six-month review for stroke survivors
Introduction The six-month review (6MR) for stroke survivors is recommended in clinical guidelines. However, the purpose of the review lacks clarity and has been implemented in var...
Statistical approaches for service delivery differentials as assessed through a composite indicator: Application to Ugandan local governments
This study assesses differentials in service delivery among Ugandan local governments through a composite indicator that consolidates essential performance data from the education, health, and water s...
Determination of silicon dioxide in fluorite by ICP OES with closed digestion and boric acid complex reaction
Fluorite is widely utilized in the new energy, semiconductor, high-end manufacturing, and steelmaking industries. The silicon dioxide (SiO₂) content is critical for both the quality evaluation of fluo...
Exploring the link between osteoporosis and stroke risk: An exploratory study based on 2017–2018 NHANES clinical data and bioinformatics analysis
Objective This study aims to explore the correlation between Osteoporosis and stroke risk, and find potential common key genes and drugs for intervention through bioinformatics met...
The role of economic stability in boosting exports in COMESA: Threshold effects analysis
Economic stability is crucial for improving export performance, particularly within regional trade blocs such as the Common Market for Eastern and Southern Africa (COMESA). However, empirical studies...
Safety outcomes of statin vs non-statin lipid-lowering interventions in patients with prior statin-associated muscle symptoms: A systematic review and meta-analysis
Background Statin-associated muscle symptoms (SAMS) are an obstacle in the prevention of cardiovascular events. A systematic assessment of the evidence of interventions in the sett...
Grape seed proanthocyanidin extract inhibits ferroptosis by activating Nrf2/HO-1 and protects against diabetic kidney disease
Background The main pathological characteristic of diabetic kidney disease (DKD) is renal dysfunction caused by tubular injury. Ferroptosis is a recently discovered form of cell de...
Unlocking cinnamon export success: Key determinants from the world’s top five producers
The purpose of this research study is to identify the factors affecting cinnamon export income (CEI) in the main five cinnamon export countries, namely China, Sri Lanka, Indonesia, Madagascar and Viet...
“I think it is our responsibility, but not solely our responsibility”: A qualitative study exploring teachers’ perspectives on promoting mental health in Northwest London primary schools
In England, 1 in 5 children and young people (CYP; aged 8–25 years) has a probable mental disorder with higher rates among those living in poverty, and among white children compared with other ethnic...
Comprehensive and deep learning classification for analyses of the biological complexity of growth and biofilms of Cobetia marina under different temperature growths
Background: Biological complexity represents a fundamental challenge in understanding microbial behavior, particularly when analyzing heterogeneous data from bacterial growth and b...
Limb swelling consistent with posttraumatic lymphedema after closed upper and lower extremity fractures: A retrospective cohort study
Introduction Secondary lymphedema is a very common clinical issue with millions of patients suffering from pain, recurrent skin infections, and the constant need for a decongestive...
Circular economy transition barriers in the construction and demolition sector
This study evaluates the readiness of Egypt’s construction sector to integrate Circular Economy (CE) principles by identifying and analyzing the main barriers to effective Construction and Demolition...
Seagrass and oyster interactions under a warming climate scenario: A mesocosm experiment
Seagrass and oyster beds are biogenic habitats of global importance in shallow coastal waters as they provide critical ecosystem functions. These habitats may be adversely affected by warming trends....
Predictors of early newborn deaths at Dar es Salaam public regional referral hospitals: A prospective observational hospital-based study
Introduction Newborn deaths are still a concern to global health systems. Increased rates of documented hospital-based births are incongruent to newborn survival chances worldwide....
Can SMEs synergistic transformation of digitization and greenization promote enterprise risk-taking?
The synergistic transformation of digitization and greenization has become an important direction in China’s economic development. Small and Medium Enterprises (SMEs) have the characteristics of small...
A putative membrane-associated YdjB-like protein from Salmonella enterica exhibits a non-canonical ACT-like fold
The Aspartokinase-Chorismate mutase-TyrA (ACT) domain is a conserved regulatory module found in a wide range of proteins involved in diverse biological processes, including amino acid metabolism, sign...
Transformer maintenance strategy based on improved risk assessment method considering operation and maintenance costs
The rapid development of modern industry cannot be separated from the support of large power equipment such as transformers. Transformers need to maintain high reliability to provide power support, an...