PLoS ONE
Articles in this Issue
Prevalence, knowledge, attitudes, and practices concerning self-medication with over-the-counter drugs among university students in Jordan: A cross-sectional study
Background The World Health Organization considers self-medication (SM) a critical global concern. SM has significant risks, including incorrect drug use, adverse reactions, misdia...
Empirical analysis of the correlation between China’s Macroeconomic Market and Crude Oil Market based on mixed-frequency group factor model
This paper examines the asymmetric correlation and dynamic interaction between China’s macroeconomic market and the global crude oil market, addressing a critical limitation in existing literature: th...
Computational repurposing of approved drugs targeting KRAS G12D and EGFR for colorectal cancer therapy
Background/objectives Colorectal cancer is characterized by various oncogenic mutations, with the KRAS G12D mutat...
Research on multi-channel access strategy based on congestion control with burst traffic in CRNs
This paper investigates a multi-channel access strategy for cognitive radio networks (CRNs) under bursty traffic conditions, with a focus on congestion control. The proposed approach integrates cross-...
Effects of stimulus emotional content on gaze pattern: An eye-tracking study
The attentional system tends to prioritize negative stimuli in the early stages of processing, favoring threat detection. However, it is unclear whether this bias is maintained or reversed toward posi...
Engagement in research capability-building: Impact on healthcare workforce attraction and retention in rural and remote Australia – A scoping review protocol
Background Geographic maldistribution of the health workforce remains a major challenge in Australia, with rural and remote communities experiencing persistent shortages that under...
Retraction: Jaeumganghwa-Tang Induces Apoptosis via the Mitochondrial Pathway and Lactobacillus Fermentation Enhances Its Anti-Cancer Activity in HT1080 Human Fibrosarcoma Cells
Introducing an integrated maternity care pathway for women with a history of small-for-gestational-age: Evaluation of its effect on care process and clinical outcomes
Introduction This study focusses on the implementation of an integrated care pathway for women with SGA in their obstetric history that pursues value-based healthcare. This study a...
Tracking Acquisition of Language in Kids (TALK) study protocol: A longitudinal investigation of infants at high vs. low risk for atypical speech and language development
The sensitive period for phonetic learning, normally considered to be between 6–12 months of age, has been demonstrated as one of the earliest milestones for la...
Assessing the sustainable development of a national research ecosystem: A generative AI-based evaluation of empirical educational research in China (2004–2023)
A nation’s progress toward Sustainable Development Goal 4 (Quality Education) depends in part on the long-term health of its educational research system, yet systematic, longitudinal assessments of su...
Molecular detection and antibiotic resistance of diarrheagenic Escherichia coli from street food and water in mukuru slums, Nairobi County
Globally, diarrheal diseases account for 550 million cases of foodborne illnesses annually. In Kenya, Escherichia coli ( E. coli...
Integration of the Pirogov interactive anatomy table into anatomy teaching: A comparative study with cadaveric dissection
Purposes Anatomy is fundamental in medical education, yet cadaveric dissection faces challenges including limited specimens, high costs, and chemical hazards. Interactive anatomy t...
From ADHD symptoms to parental stress: The roles of functional impairment, family functioning, and parental ADHD
Background Raising a child with Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with significant parental stress. However, the complex relationships between factors i...
Femoral radiographic indices for pre-operative osteoporosis screening in postmenopausal female patients undergoing total hip arthroplasty for osteoarthritis
The purpose of this study was to investigate the correlation between femoral morphological indices from anteroposterior hip radiographs and dual-energy X-ray absorptiometry-assessed bone mineral densi...
Investigating the effects of cannabinoids for the reduction of inflammation and sickle cell disease pain (CRISP); A protocol for a randomized double-blind placebo-controlled study
Sickle Cell Disease (SCD) is a hemoglobinopathy affecting millions of people globally. Pain, both acute and chronic, affects over half of those living with SCD, but treatment of chronic pain is an ong...
Lifestyle and environmental risk factors associated with cancer: A case-control study in Bangladesh
Cancer remains the second leading cause of death worldwide, with cases rising at an alarming rate. While the causes of cancer are complex and varied, certain risk factors - such as exposure to environ...
Correction: Does papillary muscle free strain has predictive value in risk stratification of patients with hypertrophic cardiomyopathy?
Correction: Toxicity of tributyltin to the European flat oyster Ostrea edulis: Metabolomic responses indicate impacts to energy metabolism, biochemical composition and reproductive maturation
Determinants of coexistence of undernutrition and anemia among children aged 6–59 months in Nepal: Evidence from the 2022 Nepal Demographic and Health Survey
Introduction Undernutrition and anemia among children aged 6–59 months are significant public health issues in developing countries like Nepal. The coexistence of these conditions...
When the outcome is compositional: A method for conducting compositional response linear mixed models for physical activity, sedentary behaviour and sleep research
Time use is compositional in nature because time spent in sleep, sedentary behaviour and physical activity will always sum to 24 h/day meaning any increase in one behaviour will necessarily displace t...
Effects of happy and angry human voice recordings on postural stability in dogs: An exploratory biomechanical analysis
Auditory stimuli are known to induce biomechanical balance responses, influencing postural stability in humans. These responses provide valuable insights into the interaction between auditory percepti...
Co-developing SHELTER (Safe, Healthy Environments and Local Transformation for Equity and Resilience) with families with lived experience of homelessness in the New York City shelter system: A community needs assessment and data collection protocol
In January 2025, the nightly census revealed that over 120,000 people were staying in New York City (NYC) shelters, including more than 41,000 children, of whom almost half were aged 0–5 years. Childr...
LHAT-YOLO: Study on intelligent monitoring algorithm for helmets at construction sites
Construction sites in civil engineering projects are prone to sudden accidents. In particular, head injuries pose a significant safety threat to construction workers. Helmets play a vital role in prot...
The sensitivity of TANDEM – A new measure of trauma competence
Background Despite international standards outlining the competence areas to be included in educational programs on trauma-informed care, a Norwegian expert group identified a lack...
Tissue-specific mitochondrial pathway remodeling linked to longevity in honeybee queens
Mitochondrial metabolism plays a critical role in determining lifespan across animal taxa. In our study, we used the Western honeybee ( Apis mellifera ) as a mo...