PLoS ONE
Articles in this Issue
Is working from home changing the meaning of work?
Especially since the COVID-19 pandemic, working from home (WFH) has become a common practice in the workplace. This raises the question of whether WFH changes the non-monetary benefits of work, such a...
Preparing the next generation of Complex Networks and Systems scientists: Evaluation results for the Complex Networks and Systems NSF research training program at Indiana University
Assessing and evaluating programmatic outcomes of graduate education programs help stakeholders understand and respond to challenges that emerge over the course of a complex academic program. Given th...
Association between acute respiratory acidosis and hyperkalemia during esophageal cancer surgery in the prone position: A multicenter retrospective observational study protocol
Introduction Esophagectomy in the prone position can induce acute respiratory acidosis. While it is known that metabolic acidosis can significantly elevate serum potassium, the eff...
Breast cancer histopathological image classification based on collaborative multi-domain feature learning
Breast cancer is a highly heterogeneous malignant tumor, and its accurate classification is of great significance for clinical diagnosis and treatment decision-making. In recent years, convolutional n...
Correction: Association and progression of multi-morbidity with Chronic Kidney Disease stage 3a secondary to Type 2 Diabetes Mellitus, grouped by albuminuria status in the multi-ethnic population of Northwest London: A real-world study
Determinants of the quality of life of care partners in the context of surgical cardiovascular interventions: A qualitative study
Introduction Cardiovascular disease (CVD) remains the leading cause of death globally, and numerous patients undergoing cardiovascular surgery rely heavily on informal care partner...
IL-18 Binding Protein, a biomarker of strength maintenance after surgery but reduced physical performance in age-related sarcopenia
Inflammation is thought to contribute to muscle loss in acute and chronic sarcopenia. Which inflammatory proteins contribute to sarcopenia in any condition is not clear. In a well-characterised cohort...
FM-DLM: A new method for image classification based on the fusion of multi-level deep learning models
Currently, deep learning models are widely used in many classification applications, but their utilization is limited by some factors. The large models can ensure classification of wide range, but the...
S100-alarmins, antenatal corticosteroids and the risk of late-onset sepsis in preterm infants: A prospective cohort study
Objectives Antenatal corticosteroids (aCS) are an important measure improving the outcome of preterm infants. Their influence on late-onset sepsis (LOS) risk remains inconclusive....
“My safe haven turned into a terror zone”: A qualitative study of family members’ experiences of violence by brain tumor patients
Background Knowledge is lacking regarding how the experience of being exposed to violence is affected when the perpetrator suffers from behavioral and person...
Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights
High blood pressure is one of the leading global causes of cardiovascular diseases. The chronic action of high concentrations of angiotensin II (Ang II) promotes arterial hypertension. Ang II acts via...
CoSMIC: A hybrid approach for large-scale, high-resolution microbial profiling of novel niches
Standard microbial profiling based on 16S rRNA (16S) sequencing suffers from a lack of primer universality, primer biases, and often yields low resolution. We introduce ‘Comprehensive Small Ribosomal...
Causal interventions in bond multi-dealer-to-client platforms
The digitalization of financial markets has shifted trading from voice to electronic channels, with Multi-Dealer-to-Client (MD2C) platforms now enabling clients to request quotes (RfQs) for financial...
Correction: Dementia and autopsy-verified causes of death in racially-diverse older Brazilians
Tunicates have a complex, highly dynamic TNF superfamily
Genes of the Tumor Necrosis Factor Superfamily (TNFSF) encode proteins with critical roles in cell signaling in animals, particularly in immunity and development. The evolution of the TNF superfamily...
Effect of esketamine-based patient-controlled intravenous analgesia on postoperative pain and quality of recovery after video-assisted thoracoscopic lobectomy: A prospective, double-blind, randomized controlled trial
Objective This double-blinded randomized study aimed to investigate the effects of esketamine-based patient-controlled intravenous analgesia (PCIA) on postoperative analgesia and q...
Adult airway management in ICU and regular floors: A prospective study as part of a healthcare improvement initiative in a tertiary care center
Background Despite recent advancements, airway management outside the operating room (OR) remains a challenging task and is associated with a high rate of complications. The first...
Carbon nanotube and carbon dot mediated plasmid DNA delivery in cowpea leaves
CRISPR-Cas9 technology has been widely used as a key molecular biology tool for crop improvement. However, the advance of this technology has been hindered by host species- or genotype-dependent tissu...
Developing a simple, cost-effective proof-of-concept vaccine candidate against EHEC for cattle
Enterohemorrhagic Escherichia coli (EHEC) is a zoonotic pathogen responsible for severe human diseases, including hemorrhagic diarrhea and hemolytic uremic synd...
Body mass index is associated with hypoglycaemia in children with acute vomiting and dehydration
Background Healthy children from 7 months to 7 years are known to be at risk for developing hypoglycaemia during prolonged fasting, particularly during acute illness with decreased...
Health insurance status and hearing aid utilization in U.S. older adults: A population-based cross-sectional study
Background The role of health insurance and its diverse hearing health benefits on hearing aid utilization is currently unknown. The objective of this study is to examine rates of...
Investigation of factors affecting annual milk yield of different goat breeds using panel data analysis
This study aims to evaluate the effects of basic biological factors such as age and lactation length on milk yield by examining the annual milk yield data of five different goat breeds (Damaskus, Pure...
Olfactory bulbectomy induces neurobiological alterations in the prefrontal cortex and hyperlocomotion in male rats
Major depressive disorder (MDD) is a leading cause of disability and encompasses various subtypes, including agitated depression which is associated with psychomotor agitation and elevated suicide ris...
Postoperative swallowing recovery in oral and oropharyngeal cancer: A prospective analysis of functional changes and adjuvant therapy effects
Dysphagia is a prevalent and debilitating sequela in patients with oral cavity and oropharyngeal cancers undergoing surgery, often complicated by adjuvant radiotherapy or chemoradiotherapy. This prosp...
Contact and complexity in English varieties: The influence of speaker numbers on syntheticity and grammaticity
Empirical research on language complexity has shown that languages and varieties can and do differ in their complexity. One of the key triggers responsible for this observed variation is language cont...