PLoS ONE
Articles in this Issue
HIV self-testing awareness among African refugee male sex workers in Italy: A mixed-methods study
HIV disproportionately affects African refugee male sex workers (ARMSWs) in Italy, who face individual, structural and systemic barriers to HIV prevention and care services. HIV self-testing (HIVST) o...
The impact of China’s clean energy market on the market connectivity of rare earth industrial chain
The accelerating global transition to clean energy underscores the critical role of rare earth elements in renewable technologies. As the world’s largest producer of clean energy and rare earth minera...
Comparing intentional and unintentional poisoning among patients presenting to the emergency department at a tertiary care center in Lebanon: A retrospective descriptive analysis
Introduction Poisoning is a significant global public health issue, contributing substantially to emergency department (ED) visits. In 2021, the WHO reported nearly 2 million death...
A deep learning-based evaluation system for child-friendly urban streets integrating abstract and concrete features—A case of Shanghai Urban Street
To address the challenges of high subjectivity, difficult data acquisition, and low efficiency in current evaluation methods for child-friendly urban streets, this study proposes a deep learning-based...
Understanding the gut microbiome through a fitness intervention of aerobic and resistance training for individuals with type 2 diabetes mellitus (GUTFIT: A Study Protocol)
Introduction Exercise is a cornerstone of type 2 diabetes (T2DM) management, yet individuals exhibit vast inter-individual variability in glycemic response to interventions. Gut mi...
Expression of Concern: Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1
Global, regional, and national burdens of attention deficit hyperactivity disorder in adolescents and young adults aged 10–24 years from 1990 to 2021: A trend analysis
Background Attention Deficit Hyperactivity Disorder (ADHD) is a major neurodevelopmental disorder among adolescents and young adults (AYAs) worldwide. However, there is still insuf...
Numerical simulation and experimental verification of venturi tube hydraulic cavitation
This study conducted a numerical simulation of hydraulic cavitation characteristics in a Venturi tube using FLUENT software. The Realizable k-ε turbulence model, Mixture multiphase flow model, and Sin...
Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype
Mesothelioma has characteristic genetic changes including inactivation of neurofibromatosis type 2 ( NF2 ) and deletion...
Factors influencing food waste reduction in University Canteens: Toward sustainable campus waste management
Objective Food waste in university canteens poses a significant challenge to advancing sustainability in higher education. Context-specific, targeted strategies remain limited. Thi...
Differential analysis of mean blood glucose levels from venous and fingertip in predicting 30-day mortality among ICU patients with severe trauma: A retrospective study utilizing the MIMIC-IV database
Background To investigate the correlation between mean blood glucose of venous (VMBG) and mean blood glucose of fingertip (FMBG) within 30 days and 30-day mortality in trauma patie...
The effect of personality traits on consumer behaviour among football fans: The mediating role of fan loyalty
The aim of the current study was to examine the impact of personality traits on consumer behaviour among football fans in a Turkish setting by focusing on the mediating role of sports fans’ loyalty. D...
Geospatial variation and associated factors of unintended pregnancy among women of reproductive age in Ethiopia: Geographically Weighted Regression Analysis
Background Unintended pregnancies are a serious public health concern that has several effects on the health of mothers and children. However, no studies have been conducted on uni...
Using machine learning to predict and analyze complex trait diseases: Lessons from a simple abstract model
The ability to predict individual genetic susceptibility to a complex trait disease is a major challenge in modern medicine. One approach to addressing this challenge utilizes an additive combination...
Assessing the multifunctionality of service crops in mediterranean vineyards using a functional trait approach
Vineyard soils face various agronomic issues such as poor organic carbon levels, erosion, fertility losses, and numerous studies have highlighted the ability of service crops to address these issues....
Implementing intravenous iron for maternal anemia in Nigeria: A qualitative study of healthcare provider experiences using the normalization process theory
Background Maternal anemia remains a significant public health challenge in Nigeria, affecting approximately 25–46% of pregnant women and contributing to adverse maternal and neona...
Development of an automatic segmentation system for anterolateral thigh flap perforators in maxillofacial reconstruction
The anterior thigh (ALT) flap is commonly used in reconstructive surgery, especially in maxillary reconstruction. Accurately identifying the perforator that supplies blood to the flap is critical for...
Developing objective tools to study rock hyrax (Procavia capensis) behaviour in the field
Animal behaviour research seeks methodological rigor and consistency within and across studies, yet maintaining shared standards requires continual evaluation. The rock hyrax ( Pro...
Effect of reconstruction plate removal on dental implants in fibula flap mandibles: A biomechanical and clinical study
Vascularized autologous bone transplantation combined with implant restoration is a preferred method for functional mandibular reconstruction. However, there is currently no consensus on whether inter...
Age-specific trends in limitations of daily activities in American adults aged 50–84 by race and ethnicity, 2000–2018
During the first decade of the 2000s, disability levels began to stagnate or increase among American adults, a sharp departure from broad declines observed in earlier decades. It is unclear whether th...
The economic burden of loiasis: A comprehensive cost-of-illness analysis of regionally representative, individual-level data from rural Gabon
Loiasis is a vector-borne filarial infection endemic to parts of sub-Saharan Africa. It disproportionally affects economically disadvantaged communities in rural, forested regions. To better understan...
Correction: Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod
Health information-seeking behavior among women with polycystic ovary syndrome: A scoping review protocol
Background Polycystic ovary syndrome (PCOS) is the most common endocrine metabolic disorder among women of childbearing age, and self-management of PCOS patients relies on their ab...
The effects of high-intensity interval training on NLRP3 inflammasome and monocyte chemokine receptors in individuals with obesity
Background/ Objectives: Obesity is a chronic disease that promotes increased cytokine production mediated by activating a complex of intracellular proteins known as the inflammasome, mainly NLRP3. The...
Robust predictors for drug response of patients with acute myeloid leukemia
The significant heterogeneity in treatment responses among patients with acute myeloid leukemia (AML) underscores the critical need for accurate drug response prediction. We developed k-Top Scoring Pa...