PLoS ONE
Articles in this Issue
Effects of interactivity, immersion, and physical discomfort on learning in VR nursing education
Background Although VR provides innovative opportunities for nursing education, little is known about how its core features immersion and interactivity shape learners’ self-efficac...
Expression of concern: HSV-2 regulates monocyte inflammatory response via the Fas/FasL pathway
Abuse recognition by shelter staff and shelter animal adopters
Science has provided insight into the physical signs of animal abuse, such as the presence of fractures in different healing stages. Possible behavioural signs of animal abuse are understudied. In stu...
Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1
Niemann-Pick disease, type C (NPC), is an inherited fatal lysosomal storage disorder caused by a mutation in the NPC1 or NPC2...
Random subspace-based ensemble classifier for high-dimensional data Using SPARK
High-dimensional data classification remains challenging for machine learning models due to sparsity and overfitting caused by the ‘curse of dimensionality‘. As the number of features increases, data...
Lessons learned using species’ distribution models for conservation planning in the Golden Gate Biosphere reserve
Conservation practitioners responsible for maintaining biodiversity and ecosystem services within protected areas require information about how dominant plant species may reassemble under rapid global...
Decoding living systems: Reassessing crop model frontiers via biological dynamics and optimized phenotype
Modeling and optimizing phenotypic performance of biological systems demands understanding how physiological processes mediate genotype-by-environment interactions. While AI-driven approaches achieve...
Effect of COVID-19 on mortality due to diabetes mellitus in Brazil: A time series analysis from 2010 to 2023
Diabetes mellitus (DM) is a major global public health concern, particularly in Brazil. This study aimed to analyze DM-related mortality trends before and during the pandemic to assess the possible in...
Prevalence and consumption patterns of energy drinks among Iraqi adolescents: A cross-sectional study
Background Most energy drinks contain significant levels of caffeine, sugar, and other ingredients, which are consumed increasingly among adolescents. Excessive energy drinks consu...
A geospatial hybrid platform to support public policy-making and monitoring for community-based food management and security in the context of global climate change: A study protocol
In Latin America, Food and Nutritional Insecurity (FNI) is a challenge, particularly in households that receive social assistance programs, where food scarcity affects up to 50% of these households. E...
Recognition of Japanese university students one year after the discharge of treated water from the Fukushima Daiichi Nuclear Power Station
The study clarified the perceptions of the Japanese university students regarding their acceptance of the discharge of treated water (DTW) into the Pacific Ocean approximately a year after the process...
Intravenous thrombolysis for acute central retinal artery occlusion: Protocol for a systematic review and individual participant data meta-analysis of randomized controlled trials
Importance Central retinal artery occlusion (CRAO) is a disabling subtype of acute ischemic stroke. It is not known whether intravenous (IV) thrombolysis delivered within 4.5 hours...
Methionine restriction provides sex-specific protection against high-fat diet-induced adiposity, peripheral insulin resistance, and neuroinflammation in FGF21-dependent and independent manners in mice
Excessive consumption of high-fat diets is linked to peripheral insulin resistance, neuroinflammation, and obesity. While dietary methionine restriction improves peripheral metabolic health, its effec...
Visual search for people wearing protective clothing in a forestial environment – Differences between gaze and behavior
To prevent hunting accidents, people in forests should be well-visible to others. However, there is debate which kind of protective clothing should be required. We created a database containing photog...
Cognitive and affective empathy in binge drinking during late adolescence
Empathy–the ability to understand and share the feelings of others–has been identified as a potential correlate of binge drinking behaviors in adolescence. Our preregistered study aimed to investigate...
Accuracy and reproducibility of tumor size measurement using a deep-learning–based CDSS in resected lung cancer
Purpose MONCAD LCT is a commercially available deep-learning based clinical decision support system (CDSS) for lung screening CT. The aim of this multicenter retrospective study wa...
Correction: Genetic analysis of drought and heat tolerance combined with Striga hermonthica resistance in tropical maize (Zea mays)
Assessing the impact of World Trade Center (WTC) exposures on post-bronchodilator lung function: Insights from WTC survivor population
Objectives To assess the effects of World Trade Center (WTC) exposures, obesity, and smoking on post-bronchodilator (post-BD) lung function in WTC Survivors....
Effect of social and digital media mental health messaging on mental health help-seeking behaviors in the sub-Saharan African population: A systematic review protocol
Mental health is a major public health concern, with disproportionate burdens in sub-Saharan Africa (SSA), where access to care is limited and stigma remains high. Social and digital platforms, includ...
Comparison of glucose concentrations in simultaneously collected plasma and serum samples from outpatients in a routine laboratory setting
Objectives Although international and national German guidelines recommend measuring glucose in venous plasma, serum remains the most commonly used sample type for glucose measurem...
Disgust in anorexia nervosa: Testing a theoretical model connecting negative body image to disgust propensity, disgust sensitivity, and self-disgust
Consistent with the view that disgust is involved in the persistence of eating disorder symptomatology, it has been found that disgust propensity is related to a negative body image. Importantly, earl...
Genomic and phylogenomic exploration of Vibrio cholerae strain SU129B isolated from Penaeus vannamei: Resistance, virulence, and evolutionary dynamics in bangladeshi aquaculture
Vibrio cholerae , a globally significant pathogen, causes both endemic and epidemic cholera and has also been associated with sporadic gastroenteritis and foodborne infections. Shr...
Conceptions of food healthiness among nutrition and food science undergraduates: A mixed-methods study in a Spanish university
Understanding how future nutrition and food professionals conceptualize healthy food and eating is key to aligning university training and professional practice with public health and sustainability g...
“Healing hands: Understanding physiotherapists’ knowledge, attitudes and barriers on pressure injury prevention in the medical wards in Jordan”
Aim to highlight the physiotherapist's knowledge and attitudes, as well as barriers and related factors affecting Pressure Injury prevention in the medical wards of Jordanian hospi...