PLoS ONE
Articles in this Issue
Estimating the causal effect of sleep duration on mental health in young adults: A meta-learner approach from physiological and nutritional perspectives
This study analyzes the causal effect of sleep duration on mental health among young adults using a meta-learner-based causal inference framework. Specifically, we applied a T-Learner model with Rando...
Multimodal instruction with AI-generated images for noun retention: Exploring semantic scene and materiality effects
This study explores the effectiveness of integrating multimodal instruction with artificial intelligence (AI)-generated visual content into English noun vocabulary instruction, as compared to text-onl...
Retraction: Caffeine Positively Modulates Ferritin Heavy Chain Expression in H460 Cells: Effects on Cell Proliferation
Preventing burnout: Community health worker perspectives on professional development and emotional labor overload - A qualitative descriptive study
Introduction Community health workers (CHWs) play a critical role in advancing health equity by bridging underserved communities with health and social services. However, expanding...
Clinical impact of broad- versus narrow-spectrum empiric therapy in acute cholangitis: A Japanese claims database study
The clinical benefit of broad-spectrum empiric therapy in patients with acute cholangitis is unclear. We aimed to evaluate the impact of broad-spectrum and narrow-spectrum empiric therapies on patient...
Designing life science assessments in the era of generative artificial intelligence
Generative artificial intelligence (GAI) algorithms have the potential to reshape education. Though GAI may help democratize access to education, it also presents many challenges for educators. Alread...
Ionized magnesium levels and atrial fibrillation in patients undergoing cardiac surgery – The iMagic Prospective Cohort Study
Background New-onset atrial fibrillation (AF) after cardiac surgery is associated with unfavorable outcomes. Electrolyte imbalances have been described as potential risk factors. T...
Appetitive traits and their associations with metabolic health outcomes among adults living with prediabetes: Results from a cross-sectional study
Appetitive traits influence eating behaviours and energy balance, potentially affecting obesity and type 2 diabetes (T2D) risk. However, evidence is limited on how these traits relate to metabolic out...
Nonlinear swing dynamics of tower crane load subject to stochastic wind excitation: A CFD/CSD coupling approach
With the expanding deployment of tower cranes in high-altitude environments, the dynamic interference of stochastic wind excitation on load swing has become a critical concern. Conventional crane dyna...
Football (Soccer) refereeing and cardiovascular health: A scoping review
Background Physical and psychological stress can precipitate Acute Coronary Syndrome (ACS) events. Football (soccer) is a popular sport globally, with referees covering significant...
Analysis of morphological, morphokinetics, cell-free DNA, microRNAs parameters to predict aneuploidy status of embryos
Background In Vitro Fertilization (IVF) is one of the most effective infertility treatments. Preimplantation genetic testing for aneuploidy (PGT-A) is invasive, high-cost, and has...
Evaluating chemical and surface stability of thermoformed and 3D-printed clear aligners after intraoral exposure
Introduction Align Technology, Inc. is a leading manufacturer of orthodontic aligners, using SmartTrack TM (LD30)...
Feasibility and agreement between TTE and intracavitary ECG for PICC tip positioning in adult oncology patients: A single-centre exploratory study
Background ECG-guided tip localization of central venous access has been clinically proven to be highly accurate and safe. However, real-time tip localization in patients with atri...
Pain and sociodemographic factors as moderating roles in the relationship between postoperative nausea–vomiting and recovery quality: A process macro modeling study from a nursing perspective on laparoscopic cholecystectomy patients
Postoperative nausea, vomiting, and pain are common complications following laparoscopic cholecystectomy, and their impact on recovery quality remains a critical concern in surgical nursing practice....
GermVarX: A Robust Workflow for Joint Germline Variant Exploration in whole-exome sequencing cohorts
Accurate identification of germline variants from whole-exome sequencing (WES) data is foundational to population genetics, disease association studies, and clinical genomics. However, variant calling...
The effects of increasing dosages of narasin on ruminal fermentation patterns, bacterial community composition, and nutrient digestibility in beef cattle receiving feedlot diets
This study evaluated the effects of increasing narasin doses on ruminal fermentation, nutrient digestibility, ruminal pH stability, papillae histology, and microbial composition in Angus cattle fed fe...
Estimating the velocity and direction of African Swine Fever spread in wild boar populations in South Korea using Trend-Surface Analysis
African swine fever (ASF) is a lethal disease of swine that has spread across Asia since its introduction in 2018. South Korea first reported the disease in September 2019 in domestic pigs, and since...
Where extended reality and AI may take us: Ethical issues of impersonation and AI fakes in social virtual reality
We describe a study based on a panel discussion that took place in social virtual reality (VR) at the conference IEEE VR 2025. Each panellist was embodied in a virtual body that looked like themselves...
Facility-level integration of hypertension and diabetes services with HIV treatment in sub-Saharan Africa: Observational evidence from Malawi, South Africa, and Zambia
Background A growing number of people living with HIV (PLHIV) also have non-communicable diseases (NCDs). Shifting to an integrated delivery model may facilitate care-seeking and i...
Identifying where Japanese agriculture is most at risk: A longitudinal analytical framework based on municipal boundaries as of 1950 for workforce decline and aging (2005–2020)
Japan’s agricultural workforce is shrinking and aging, posing a significant social issue. Yet, fundamental analysis—quantifying and mapping where and how rapidly this demographic shift is progressing—...
Language barriers in pediatric food allergy care: A single-center study on healthcare disparities
Background There is limited knowledge of healthcare utilization and food allergy outcomes among non-primary English-speaking patients in the United States, despite language barrier...
Willingness, motivators and barriers to time bank participation: A scoping review
This scoping review systematically identifies the extent and nature of evidence regarding willingness, motivators, and barriers influencing community participation in time bank systems, with a focus o...
Nutrient-dense snack bars from biofortified crops to enhance school children’s micronutrient intake in Tanzania
Recent national surveys show that anaemia affects approximately 30–40% of school-aged children and up to 50% of adolescents in Tanzania, with prevalence exceeding 50% in some regions, underscoring the...
Exploring EFL primary school teachers’ behavioral intention towards digital game-based learning
This study investigates the factors influencing English as a Foreign Language (EFL) primary school teachers’ behavioral intention (BI) to integrate Digital Game-Based Learning (DGBL) into their teachi...
The theoretical understanding of risk perception and dual-method contraceptive decision-making among Texas adolescent and young adult cisgender females
In this paper we use a constructivist grounded theory approach to conduct individual, qualitative interviews with a racially and ethnically diverse group of adolescent and young adult cisgender female...