PLoS ONE
Articles in this Issue
Finite mixtures of functional graphical models: Uncovering heterogeneous dependencies in high-dimensional data
Graphical models have been widely used to explicitly capture the statistical relationships among the variables of interest in the form of a graph. The central question in these models is to infer sign...
Evaluation of efficacy of GCSF in reducing neutropenia among carcinoma patients undergoing anti-cancer chemotherapy. A prospective cohort study
The use of granulocyte colony-stimulating factor (GCSF) to control febrile neutropenia (FN) caused by anti-cancer chemotherapy is well documented but it still needs to evaluated with respect to the sp...
Nasopharyngeal carriage of Streptococcus pneumoniae among Brazilian children: Interplay with viral co-infection
Nasopharyngeal transmission of Streptococcus pneumoniae is a prerequisite for the development of pneumococcal diseases. Previous studies have reported a relationship between respiratory viruses and S....
Correction: A secreted proteomic footprint for stem cell pluripotency
Correction: Self-reported food intolerance, dietary supplement use and malnutrition in chronic inflammatory bowel diseases: Findings from a cross-sectional study in Lebanon
Virological outcomes of antiretroviral therapy and its determinants among HIV patients in Ethiopia: Implications for achieving the 95–95–95 target
Background Despite significant advancements in HIV treatment, virological outcomes remain a critical issue. Ethiopia did not meet the 90:90:90 targets set for 2020, which aimed for 90% of people on an...
A systematic review to identify research gaps in studies modeling MenB vaccinations against Neisseria infections
The genus Neisseria includes two major human pathogens: N. meningitidis causing bacterial meningitis/septicemia and N. gonorrhoeae causing gonorrhoea. Mathematical models have been used to simulate th...
Barriers and facilitators to implementing comprehensive sex education in Texas public schools: A qualitative study
Introduction In Texas, the adolescent birth rate is higher than the national average and STIs have steadily increased over the last decade. Sex education is not mandated in Texas a...
Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes
Background Chorioamnionitis is recognized as a major consequence of preterm premature rupture of membranes (PPROM), and a frequent cause of neonatal morbidity and mortality. The association between fe...
Correction: Exploring the impact of trait number and type on functional diversity metrics in real-world ecosystems
Impact of regenerative procedure on the healing process following surgical root canal treatment: A systematic review and meta-analysis
Introduction Different Guided Tissue Regeneration (GTR) procedures, such as membranes, bone substitute materials, and Autologous Platelet Concentrates (APCs), have been applied after surgical root can...
Inpatient treatment for severe obesity: A retrospective cohort study in Brazil, comparing exposure variables in a secondary data analysis
Introduction: Very low-calorie diets with hospitalization have demonstrated promise as a viable therapeutic option for severe obesity and its associated comorbidities. However, large studies providing...
Contribution of paranasal sinus, chest, and abdomen/pelvis computed tomography in patients with febrile neutropenia
Objective Febrile neutropenia (FN) is a serious clinical event, associated with significant morbidity and mortality. Imaging has a central role in the identification of the fever cause. The study obje...
Exploring happiness factors with explainable ensemble learning in a global pandemic
Happiness is a state of contentment, joy, and fulfillment, arising from relationships, accomplishments, and inner peace, leading to well-being and positivity. The greatest happiness principle posits t...
Predicting learning achievement using ensemble learning with result explanation
Predicting learning achievement is a crucial strategy to address high dropout rates. However, existing prediction models often exhibit biases, limiting their accuracy. Moreover, the lack of interpreta...
Prognostic significance of total choline on in-vivo proton MR spectroscopy for prediction of late recurrence in patients with hormone receptor-positive, HER2-negative early breast cancer
Purpose In-vivo proton magnetic resonance spectroscopy (MRS) is a non-invasive method of analyzing choline metabolism that has been used to predict breast cancer prognosis. A strong choline peak may b...
The social welfare effect of e-commerce product reputation information asymmetry from the perspective of network externality
Reputation is the most important intangible asset of merchants. In the e-commerce platform market, reputation information has become an important signal of product quality. However, with increasingly...
Measuring four facets of emotion beliefs in Germany: A German-language adaptation of the EBQ and its comparability across gender and different emotion abilities
Adaptive emotion regulation, involving the modulation of positive and negative emotions based on goals, is a crucial function for a person’s mental health and general well-being. Factors influencing s...
Global prioritization schemes vary in their impact on the placement of protected areas
In response to global declines in biodiversity, many global conservation prioritization schemes were developed to guide effective protected area establishment. Protected area coverage has grown dramat...
An investigation of feature reduction, transferability, and generalization in AWID datasets for secure Wi-Fi networks
The widespread use of wireless networks to transfer an enormous amount of sensitive information has caused a plethora of vulnerabilities and privacy issues. The management frames, particularly authent...
Correction: Psychosocial and sociodemographic factors associated with gestational blood glucose levels in women attending public hospitals: Results from baseline of MAASTHI cohort
Impact of posterior septectomy on olfaction in endoscopic endonasal transsphenoidal surgery
Background Endoscopic endonasal transsphenoidal surgery is widely used to resect pituitary adenomas, yet its impact on olfactory function after resection of the posterosuperior nasal septum remains a...
Predicting prosthetic gait and the effects of induced stiff-knee gait
Prosthetic gait differs considerably from the unimpaired gait. Studying alterations in the gait patterns could help to understand different adaptation mechanisms adopted by these populations. This stu...
Gut microbiota dysbiosis, sarcopenia, osteoporosis and osteosarcopenia in older people: A systematic review protocol
Introduction Sarcopenia and Osteoporosis are two prevalent conditions in the older population and are defined by low strength, muscle quality/volume and low Bone Mineral Density, respectively. When th...
Block selection in multiblock partial least squares for modeling genotype-phenotype relations in Saccharomyces
In data-based modeling, correlations between explanatory variables often lead to the formation of distinct gene blocks. This study focuses on identifying influential gene blocks and key variables with...