PLoS ONE
Articles in this Issue
Cell recruitment and the origins of Anterior-Posterior asymmetries in the Drosophila wing
The mechanisms underlying the establishment of asymmetric structures during development remain elusive. The wing of Drosophila is asymmetric along the Anterior-Posterior (AP) axis, but the development...
Development and validation of the health education demand scale for HPV infected patients based on KANO model
Objective The purpose of this study is to develop and validate the scale of health education demand of patients with HPV infection based on KANO model, so as to provide a tool for further exploring th...
Suboptimal dietary knowledge predicts lower diet quality for cancer prevention among university students in Beirut
University students are at a pivotal stage of shaping cancer risk factors. Little is known about their dietary behavior in Lebanon, a country heavily burdened by cancer. This cross-sectional study ass...
Correction: Calcium-Activated-Calcineurin Reduces the In Vitro and In Vivo Sensitivity of Fluconazole to Candida albicans via Rta2p
Early neutrophil activation and NETs release in the pristane-induced lupus mice model
Background NETosis is recognized as an important source of autoantigens. Therefore, we hypothesized whether the pristane-induced lupus mice model shows early activation of neutrophils, the presence of...
Optimizing Kernel Extreme Learning Machine based on a Enhanced Adaptive Whale Optimization Algorithm for classification task
Data classification is an important research direction in machine learning. In order to effectively handle extensive datasets, researchers have introduced diverse classification algorithms. Notably, K...
The impact of the centralized volume-based procurement policy on Chinese pharmaceutical manufacturing firms’ R&D investment: A difference-in-differences approach
Centralized drug procurement is a common practice worldwide to relieve the healthcare burden and promote high-quality development in the pharmaceutical industry. However, scholars have not yet reached...
Assessing the drivers of sexual behavior among youth and its social determinants in Nepal
Introduction Sexual behavior among youth is a public health concern, particularly in contexts where cultural norms, socio-economic factors, and access to comprehensive sexual education play pivotal ro...
Bacteriological quality of drinking water and its associated factors in Ethiopia: A systematic review and meta-analysis
Introduction Drinking contaminated water is a significant cause of mortality and morbidity in Sub-Saharan Africa, where access to safe drinking water is limited. Although numerous studies have investi...
Incorporating earned value management into income statements to improve project management profitability and elevate application in the business and management
Our goal is to improve Project Management (PM) profitability and reduce discrepancies in information among stakeholders, which can result in conflicts. This will be accomplished by incorporating Earne...
Disparities in time to treatment initiation of invasive lung cancer among Black and White patients in Tennessee
Background Early initiation of treatment for lung cancer has been shown to improve patient survival. The present study investigates disparities in time to treatment initiation of invasive lung cancer...
Being “resilient” and achieving “resilience”: From governmental discourses to the national research agenda in the contexts of food insecurity and cost of living
The concept of ‘resilience’ is pervasive, permeating academic disciplines and political discourses. This paper considers (i) the construal of ‘resilience’ in the contexts of food insecurity and cost-o...
Age-related disparities in national maternal mortality trends: A population-based study
Objective An upward trend in maternal age has been observed in the United States (US) over the last twenty years. The study objective was to examine the association of maternal age with maternal morta...
Navigating technological innovation and rising costs: Assessing economic performance in Chinese manufacturing
Economic performance is an important indicator of the efficiency and quality of a company’s production, which is closely related to the profitability of the company and is crucial for the development...
Exploring LGBTQ+ youth well-being: Utilizing a mixed-method approach to uncover insights, needs, and strategies of LGBTQ+ youth in Northwest Arkansas
Objective This study investigates the well-being and needs of LGBTQ+ youth in Northwest Arkansas, aiming to understand factors influencing their quality of life and inform supportive policies and prac...
Prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex, based on 134,603 refractive surgery candidates
Purpose To examine the prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex. Methods Anisometropia was analyzed for subjective refraction. In total,...
Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy
Liver cancer is the sixth most frequent malignancy and the fourth major cause of deaths worldwide. The current treatments are only effective in early stages of cancer. To overcome the therapeutic chal...
Creating a culture, not just a space—A qualitative investigation into reflective practice groups in inpatient mental health settings from the perspectives of facilitators and attendees
Background Working in inpatient mental health settings is often characterised by highly emotive work and staff shortages. Despite the suggested benefits of reflective practice groups on staff well-bei...
Self-efficacy and career intention: Uncovering the underlying processes
This study aims to suggest and empirically evaluate a conceptual framework that investigates the association of career self-efficacy with career intentions, emphasizing on the specific and sequential...
Effectiveness of robot-assisted task-oriented training intervention for upper limb and daily living skills in stroke patients: A meta-analysis
Purpose Stroke is one of the leading causes of acquired disability in adults in high-income countries. This study aims to determine the intervention effects of robot-assisted task-oriented training on...
Social media-based Health Education plus Exercise Program (SHEEP) to improve muscle function among young-old adults with possible sarcopenia in the community: A feasibility study protocol
Background Despite the comparatively high prevalence of possible sarcopenia among young-old adults in the community, there is currently no available and effective social media-based intervention to in...
New-type urbanization and rural revitalization: A study on the coupled development of the Yangtze River Economic Belt, China
The coupled development of new-type urbanization (NTU) and rural revitalization (RR) represents a critical proposition put forth by China for forging a novel paradigm of urban-rural relationship. Init...
Sex differences in psychiatric comorbidities of attention-deficit/hyperactivity disorder among children, adolescents, and adults: A nationwide population-based cohort study
This cross-sectional, nationwide, population-based study aimed to elucidate sex differences in psychiatric comorbidities of Attention-deficit/hyperactivity disorder (ADHD) across children, adolescents...
Investigating the point prevalence, types, severity, causes and predictors of vaccines administration errors during COVID-19 pandemic in Jordan
Background There is a paucity of research regarding COVID-19 vaccines administration errors (VAEs) during the COVID-19 pandemic. This study aimed to investigate the prevalence, types, severity, causes...
Late-stage changes in the composition of cell walls of maize plants expressing an apoplast targeted, senescence enhanced fungal ferulic acid esterase, and the subsequent effects on tissue saccharification
Using maize plants expressing an apoplast targeted Aspergillus niger ferulic acid esterase (FAEA), with FAEA driven by a Lolium multiflorum senescence enhanced promoter (LmSee1), we extended measureme...