PLoS ONE
Articles in this Issue
Uncovering NK cell sabotage in gut diseases via single cell transcriptomics
The identification of immune environments and cellular interactions in the colon microenvironment is essential for understanding the mechanisms of chronic inflammatory disease. Despite occurring in th...
Backbone extraction through statistical edge filtering: A comparative study
The backbone extraction process is pivotal in expediting analysis and enhancing visualization in network applications. This study systematically compares seven influential statistical hypothesis-testi...
Risk assessment and prevention in airport security assurance by integrating LSTM algorithm
The risk assessment and prevention in traditional airport safety assurance usually rely on human experience for analysis, and there are problems such as heavy manual workload, excessive subjectivity,...
Investigation of alpha-glucosidase inhibition activity of Artabotrys sumatranus leaf extract using metabolomics, machine learning and molecular docking analysis
One way to treat diabetes mellitus type II is by using α-glucosidase inhibitor, that will slow down the postprandial glucose intake. Metabolomics analysis of Artabotrys sumatranus leaf extract was use...
An overview of healthcare-associated Candida auris outbreaks in Ministry of Health hospitals–Saudi Arabia 2020–2022; Retrospective multicentric study
Background Candida auris (C. auris) is an emerging fungus pathogen associated with nosocomial infections that is seen as a serious global health issue. Aim To describe the epidemiology and features...
Correction: Will R&D make investors more tolerant? Analysis based on the performance forecast of Chinese listed companies
Monocyte-cancer cell fusion is mediated by phosphatidylserine—CD36 receptor interaction and induced by ionizing radiation
Emerging evidence suggests that fusion of cancer cells with leucocytes, such as macrophages, plays a significant role in cancer metastasis and results in tumor hybrid cells that acquire resistance to...
Unravelling the complexity of the relationship between social support sources and loneliness: A mixed-methods study with older adults
Loneliness is an increasingly significant social and public health issue in contemporary societies. The available evidence suggests that social support is one of the key psychosocial processes for the...
Effect of coenzyme Q10 on tibial fracture resistance in nicotine-exposed rats
The study aimed to evaluate the potential protection against fractures of oral Q10 supplementation in the tibias of rats exposed to nicotine. Nicotine is known to negatively impact bone density and in...
Mathematical modelling approach to understanding the effect of Mg-rich synthetic gypsum used as fertilizer on growth of Hevea brasiliensis in acid soils
Knowledge of plant growth dynamics is essential where constraints such as COVID-19 lockdown restrictions have limited its field establishment. Thus, modeling can be used to predict plant performance w...
Virtual screening and molecular dynamics simulations identify repurposed drugs as potent inhibitors of Histone deacetylase 1: Implication in cancer therapeutics
Epigenetic processes are the critical events in carcinogenesis. Histone modification plays a crucial role in gene expression regulation, where histone deacetylases (HDACs) are key players in epigeneti...
Speed-dependent changes in the arm swing during independent walking in individuals after stroke
Background Increasing one’s walking speed is an important goal in post-stroke gait rehabilitation. Insufficient arm swing in people post-stroke might limit their ability to propel the body forward and...
Object detection in motion management scenarios based on deep learning
In athletes’ competitions and daily training, in order to further strengthen the athletes’ sports level, it is usually necessary to analyze the athletes’ sports actions at a specific moment, in which...
Reverse shoulder arthroplasty in revision surgery—Indications and results
Background The number of reverse shoulder arthroplasty (RSA) procedures performed worldwide has increased over the last 10 years, with a corresponding increase in revision shoulder arthroplasty (SRSA)...
Magnitude of telemedicine utilization and associated factors among health professionals working at selected public hospitals in Southern Ethiopia
Background Despite the immense potential of telemedicine, its implementation in Ethiopia and other developing nations has faced formidable challenges, leading to disappointingly low utilization rates....
Potential associations of selected polymorphic genetic variants with COVID-19 disease susceptibility and severity
In this study, we analyzed the potential associations of selected laboratory and anamnestic parameters, as well as 12 genetic polymorphisms (SNPs), with clinical COVID-19 occurrence and severity in 86...
miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway
Porcine epidemic diarrhea virus (PEDV) is a significant pathogen affecting swine, causing severe economic losses worldwide. This study explores the regulatory role of miRNA-328-3p to ZO-1 expression a...
Research on the mechanism by which digital transformation peer effects influence innovation performance in emerging industries: A case study of China’s photovoltaic industry
The exploration of digital transformation peer effects on the innovation performance of emerging industries is crucial for analyzing the underlying mechanisms of digital transformation, optimizing res...
Does music counteract mental fatigue? A systematic review
Introduction Mental fatigue, a psychobiological state induced by prolonged and sustained cognitive tasks, impairs both cognitive and physical performance. Several studies have investigated strategies...
Networks of care for optimizing Primary Health Care Service Delivery in Ethiopia: Enhancing relational linkages and care coordination
Introduction Ethiopia has made notable progress in reducing maternal and perinatal mortality, yet challenges remain in meeting the 2030 Sustainable Development Goals. Persistent issues such as low ser...
Disability and depression among stroke survivors attending rehabilitation facilities at three designated tertiary care hospitals in Bangladesh: A cross-sectional study
Background Poststroke depression (PSD) is a highly prevalent and serious mental health condition affecting a significant proportion of stroke survivors worldwide. While its exact causes remain under i...
Seizures elicited by transcorneal 6 Hz stimulation in developing rats
Seizures elicited by corneal 6-Hz stimulation are widely acknowledged as a model of temporal lobe seizures. Despite the intensive research in rodents, no studies hint at this model in developing anima...
Multi-feature fusion-based consumer perceived risk prediction and its interpretability study
E-commerce faces challenges such as content homogenization and high perceived risk among users. This paper aims to predict perceived risk in different contexts by analyzing review content and website...
Forward-backward translation, content validity, face validity, construct validity, criterion validity, test-retest reliability, and internal consistency of a questionnaire on patient acceptance of orthodontic retainer
This study aimed to assess the validity and reliability of a questionnaire on patient acceptance of orthodontic retainers. The original questionnaire was forward- and backward-translated, followed by...
An exploratory review of resiliency assessments after brain injury
Background People with brain injury can have lower resiliency compared to the general public. Yet, resiliency facilitates positive processes to negotiate adversity after brain injury. Therefore, measu...