PLoS ONE
Articles in this Issue
FIRM image analysis: A machine learning workflow for quantifying extracellular matrix components from electron microscopy images
The extracellular matrix (ECM) is a complex network of biomolecules that plays an integral role in the structure, processes, and signaling mechanisms of cells and tissues. Identifying and quantifying...
Preparing controlled low strength materials with cement-treated construction waste clay improved by sodium hexametaphosphate
To solve the disposal of large quantities of construction waste clay, this study proposes a new method for preparing controlled low strength materials (CLSM). Flow tests, unconfined compressive streng...
Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce
Production of lettuce (Lactuca sativa) within vertical farms is an expanding segment of controlled environment agriculture—precise manipulation of environmental parameters including mean daily tempera...
Effect of the hour-1 bundle on clinical outcomes in patients with sepsis and septic shock: A protocol for systematic review and meta-analysis
Background According to the 2018 bundle guidelines of the Surviving Sepsis Campaign, many emergency departments and intensive care units currently adopt the hour-1 bundle as a standard practice for se...
Adaptive enhancement of shoulder x-ray images using tissue attenuation and type-II fuzzy sets
Shoulder X-ray images typically have low contrast and high noise levels, making it challenging to distinguish and identify subtle anatomical structures. While existing image enhancement techniques are...
Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis
Introduction Chronic kidney disease is a major public health concern among people living with human immunodeficiency virus (PLWHIV) who are taking tenofovir disoproxil fumarate-based regimen. Despite...
Applying a quantitative fire risk assessment method in hospital settings: Case study
Understanding and mitigating fire risks in healthcare settings are crucial for ensuring the safety of individuals, especially during the current pandemic, which has increased the use of oxygen-supply...
Computational modeling of bone allograft reconstruction following femoral shaft tumor resection: Investigating the impact of supplementary plate fixation
Background and objective The use of bone allograft reconstructions after tumor resection can introduce significant complications. Stable fixation is required to decrease the incidence of mechanical co...
Exploring the associations between the biomechanical and psychological mechanistic pathways of lower back pain development amongst persons with lower-limb amputation: A study protocol
Introduction The global rise in lower-limb amputations is mainly due to diabetes and vascular complications. Amputations cause serious physical and psycho-social disabilities which impair locomotion a...
Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment
Background While drug therapy and allergen immunotherapy are useful for alleviating symptoms of seasonal allergic rhinitis (AR), existing therapeutic options remain limited. Cuproptosis is a novel for...
Mindfulness-based (non-contact) boxing therapy (MBBT) for depression and anxiety: A feasibility study
Objectives Mindfulness-Based (non-contact) Boxing Therapy (MBBT) is a novel intervention designed to empower and promote self-agency through behavioral interventions, while reducing barriers to exerci...
Ecological modelling: A computational analysis of air pollution discourses in English print media of India and Pakistan
The present study investigates air pollution dynamics through newspaper discourse in India and Pakistan, where both countries rank among the top five countries affected by air pollution. The study foc...
Cryptic coral community composition across environmental gradients
Cryptic genetic variation is increasingly being identified in numerous coral species, with prior research indicating that different cryptic genetic lineages can exhibit varied responses to environment...
Machine learning-based anomaly detection and prediction in commercial aircraft using autonomous surveillance data
Regarding the transportation of people, commodities, and other items, aeroplanes are an essential need for society. Despite the generally low danger associated with various modes of transportation, so...
What determines investment in the Nippon Individual Savings Account? an investigation of Japan’s tax-exempt investment account
In 2014, the Japanese government introduced the Nippon Individual Savings Account (NISA) to encourage tax-exempt investment and asset accumulation. In January 2024, the NISA underwent significant rest...
TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep
The development of secondary hair follicles influences the quality of sheep wool. However, the mechanism by which proteins mediate the fetal development of secondary hair follicles remains unknown. In...
Death and disappearance: Measuring racial disparities in mortality and life expectancy among people in state prisons, United States 2000–2014
Background Research on carceral institutions and mortality finds that people in prisons and jails have a high risk of death immediately following release from custody and that whil...
Investigation of injury severity level in truck-related crashes at school zones using mixed generalized ordered models
The number of truck registrations is steadily increasing in Korea. The proportion of truck deaths compared to the total number of traffic crashes was 23.9%, which is significantly higher than that of...
Correction: Relevance of COVID-19 vaccine on the tourism industry: Evidence from China
Larger models yield better results? Streamlined severity classification of ADHD-related concerns using BERT-based knowledge distillation
This work focuses on the efficiency of the knowledge distillation approach in generating a lightweight yet powerful BERT-based model for natural language processing (NLP) applications. After the model...
Retraction: Advancements in intrusion detection: A lightweight hybrid RNN-RF model
Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study
Ovarian cancer, a formidable gynaecological malignancy, poses a significant global health challenge, and it is characterised by late-stage diagnosis and a high mortality rate. Even in its early stages...
Behavioral intention to use electronic cigarettes in the Philippines: The role of social influence, knowledge, price and health impact
Electronic cigarettes or e-cigarettes have gained significant popularity as an alternative to traditional cigarettes, yet limited research has examined the factors influencing their adoption, particul...
Efficacy of probiotic supplements in the treatment of sarcopenia: A systematic review and meta-analysis
Although some studies have confirmed the efficacy of probiotics in the treatment of sarcopenia, the intervention of sarcopenia is a comprehensive consideration of many factors, and the efficacy of pro...
Saturated Transposon Analysis in Yeast as a one-step method to quantify the fitness effects of gene disruptions on a genome-wide scale
Transposon insertion site sequencing (TIS) is a powerful tool that has significantly advanced our knowledge of functional genomics. For example, TIS has been used to identify essential genes of...