PLoS ONE
Articles in this Issue
Dry eye disease treatment improves subjective quality-of-life responses in patients with AMD, independent of disease stage
Purpose To determine the impact of severity of age-related macular degeneration (AMD) on subjective treatment response in patients treated for dry eye disease. Methods A total of 203 eyes diagnosed...
Machine learning identifies the association between second primary malignancies and postoperative radiotherapy in young-onset breast cancer patients
Background A second primary malignant tumor is one of the most important factors affecting the long-term survival of young women with breast cancer (YWBC). As one of the main treatments for breast can...
Analysis of the kinematic pattern of free throw by wheelchair basketball athletes: a systematic review
Athletes are stratified into classes that range from 1.0 to 4.5 points subdivided at intervals of 0.5 points in the Wheelchair Basketball (WCB) modality. The discussion regarding the non-utilization o...
Assessment of contamination of natural waters with radionuclides and heavy metals the case of Karabulak creek at the Semipalatinsk Test Site
This paper presents research data on water contamination levels of artificial radionuclides and heavy metals in Karabulak Creek at the Semipalatinsk Test Site. The uranium isotopic composition has bee...
Emergency care utilization by refugee children compared to controls: A statewide database analysis
Background Refugees face barriers to accessing healthcare despite provision of short-term services after arrival. Limited access to sustained primary care may lead to increased emergency department (E...
Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway
The nutraceutical COMP-4 –consisting of L-citrulline, ginger extract, and herbal components Paullinia cupana and muira puama–has been shown previously to stimulate the production of nitric oxide (NO)...
PGC-1α activation to enhance macrophage immune function in mycobacterial infections
Nontuberculous Mycobacteria (NTM) are a heterogeneous group of environmental microorganisms with distinct human pathogenesis. Their incidence and prevalence are rising worldwide, due in part to elevat...
Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment
Despite the availability of various treatment options, glioblastoma (GBM) remains an extremely aggressive form of glioma with a poor prognosis. In recent studies, regulatory cell death (RCD) has been...
Prevalence of prolonged transitional neonatal hypoglycemia and associated factors in Ethiopia: A systematic review and meta-analysis
Introduction Most neonates experience transient hypoglycemia, which typically responds well to treatment and is associated with a favorable prognosis. However, hypoglycemia persisting beyond 48 hours,...
Calculating age-specific prevalence rates of female genital mutilation / cutting (FGM/C) for use as an input variable in extrapolation calculations and as predictors of future prevalence in countries of origin
This paper proposes a refined method for calculating age-specific prevalence rates of Female Genital Mutilation/Cutting (FGM/C) to enhance the accuracy of estimates calculated using Yoder and Van Bael...
Comparisons of performances of structural variants detection algorithms in solitary or combination strategy
Structural variants (SVs) have been associated with changes in gene expression, which may contribute to alterations in phenotypes and disease development. However, the precise identification and chara...
Surviving a crisis: A multilevel model of leadership styles, employees’ psychological capital and organizational resilience
Building on the emerging research on organizational resilience in crisis, we tested a model of transformational and directive leadership styles and their association with organizational resilience in...
Comparative analysis of grape berry microbiota uncovers sour rot associates from a Maryland vineyard
Grape sour rot (GSR) is a disease complex involving fungi and bacteria that can cause significant yield losses of susceptible varieties. It is widely spread in the eastern U.S. and other grape-growing...
Prevalence and antibiotic resistance of Escherichia coli in urban and peri-urban garden ecosystems in Bangladesh
In the past decade, there has been a notable rise in foodborne outbreaks, prominently featuring Escherichia coli as a primary pathogen. This bacterium, known for its prevalence in foodborne illnesses...
Postnatal cytomegalovirus infection and its effect on hearing and neurodevelopmental outcomes among infants aged 3–10 months: A cohort study in Eastern Uganda
Background Hearing impairment and neurodevelopmental disorders pose a significant global health burden in children. The link between postnatal cytomegalovirus (CMV) infection and these outcomes remain...
Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review
Background A recent resurgence of bacterial sexually transmitted infections (STIs) is placing a major burden on high-risk populations, physicians, and the healthcare system. Treatment in the form of a...
A parametric bootstrap control chart for Lindley Geometric percentiles
Control charts are vital for quality control and process monitoring, helping businesses identify variations in production. Traditional control charts, like Shewhart charts, may not work well for skewe...
Analysis of attacking styles and goal-scoring in the 2021/22 Women’s Super League
The rapid rise in elite women’s football has increased the demand for female specific research to enable more accurate and appropriate assessments of tactical performance. Thereby, this study aimed to...
Fund style drift and fund performance: Evidence from China
This study selects the quarterly data of all equity and equity-oriented hybrid open-end funds in China from 2007 to 2022 as the research sample, and examines the impact of fund style drift on fund ret...
Genome-wide association study reveals major loci for resistance to septoria tritici blotch in a Tunisian durum wheat collection
Septoria tritici blotch (STB) is a devastating fungal disease affecting durum and bread wheat worldwide. Tunisian durum wheat landraces are reported to be valuable genetic resources for resistance to...
Innovative approach of nomography application into an engineering educational context
Nomography is considered a branch of mathematics introduced by Maurice d’Ocagne in 1884 in France. The past century saw nomography grow as a graphical computing method used by scientists and engineers...
Vegetation restoration effectiveness with main factors in the Beijing-Tianjin sandstorm source region during 2000–2020, China
The Beijing-Tianjin Sandstorm Source Region (BTSSR), a region with significant vegetation degradation in China, has been subjected to ecological engineering intended to curb vegetation browning. Never...
Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model
Severe axonal damage in the peripheral nerves results in retrograde degeneration towards the central side, leading to neuronal cell death, eventually resulting in incomplete axonal regeneration and fu...
Evaluating the impact of added greenery on perceived factors of an urban environment in virtual reality
The wellbeing effects of urban greenspace are well established, but may be more attributable to pedestrians’ perceptions than objective levels of greenery. An immersive virtual environment was designe...
An intelligent spam detection framework using fusion of spammer behavior and linguistic
The diverse types of fake text generation practices by spammer make spam detection challenging. Existing works use manually designed discrete textual or behavior features, which cannot capture complex...