PLoS ONE
Articles in this Issue
Interventions to improve adherence/compliance to home noninvasive positive pressure ventilation in stable hypercapnic chronic obstructive pulmonary disease patients: A systematic review protocol
Introduction Chronic obstructive pulmonary disease (COPD) is a prevalent condition often leading to chronic hypercapnic respiratory failure in its advanced stages. Home noninvasive positive pressure v...
Development and validation of predictive models for diabetic retinopathy using machine learning
Objective This study aimed to develop and compare machine learning models for predicting diabetic retinopathy (DR) using clinical and biochemical data, specifically logistic regression, random forest,...
Pickup and delivery planning for the crowdsourced freight delivery routing problem
Pickup and delivery problem (PDP) and dynamic vehicle routing problem (DVRP) are two key components of crowdsourced freight delivery services. Although previous research has focused predominantly on s...
Assessing the impact of a negative air ionization system on particulate matter and gaseous pollutants in the swine farrowing environment
Air quality on swine farms has long been a concern for both human and swine health as it has been previously linked with respiratory issues; the main cause being the inhalation of small airborne parti...
Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery
Background Obesity is a growing health concern worldwide, including United Arab Emirates. Bariatric surgery is an effective treatment option, with to date unclear weight loss mechanisms. In this prosp...
Association between neutrophile-to-lymphocyte ratio and risk of deep vein thrombosis in patient receiving lower extremity orthopedic surgery: A meta-analysis
Objective This meta-analysis aimed to quantitatively synthesize evidence on the association between the preoperative neutrophil-to-lymphocyte ratio (NLR) and the risk of deep vein thrombosis (DVT) in...
The effect of labour hopscotch framework on maternal and neonatal outcomes in pregnant women: A randomized controlled trial
The Labour Hopscotch Framework (LHF) is a practical tool designed for women to use with the support of their birthing partners throughout labor and birth. It was specifically developed to help midwive...
Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays
Fusarium wilt is a devastating disease that affects banana crops worldwide. In Ecuador, bananas are one of the most important commodities and staple food. Nanoparticles are emerging as innovative solu...
Growth of Spirulina spp. at different temperatures and their impact on pigment production, oxidants and antioxidants profile
The study investigated the effect of different temperatures on the growth, pigment production, oxidative stress markers, and antioxidant profile of Spirulina spp. The results showed that the maximum g...
Protocol to establish standards for the elements infection prevention and control programs and competencies for infection control professionals in Australian residential aged care homes
The COVID-19 pandemic elucidated the importance of infection prevention and control (IPC) in residential aged care homes (RACHs), both on the health and wellbeing of its residents, and the staff and c...
Longitudinal healthcare use after pediatric brain injury: A population-based birth cohort study
Background Traumatic brain injury is a chronic disease with lifelong consequences. In children, it can affect developmental milestones. Longitudinal data on brain injury and long-term healthcare use i...
Research on three-dimensional path planning of unmanned aerial vehicle based on improved Whale Optimization Algorithm
Addressing the insufficient optimization performance in drone 3D path planning and the issues of inadequate optimization precision and tendency to fall into local optima in the existing Whale Optimiza...
Influencing consumer perceptions in green tourism: criteria and strategies for effective destination branding
As the global shift towards sustainable tourism intensifies, the need for effective destination branding strategies becomes increasingly important. This study investigates and prioritizes these strate...
Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA
Besides the abundant ribosomal and transfer RNA transcripts (rRNA and tRNA, respectively), there are tens of thousands of long coding (mRNA) and non-coding transcripts (lncRNA) within each cell whose...
Comparative efficacy and safety of dupilumab versus newly approved biologics and JAKi in pediatric atopic dermatitis: A systematic review and network meta-analysis
Background The newly approved biologics and Janus kinase inhibitors (JAKi) for pediatric atopic dermatitis (AD) offer additional options for clinical treatment. However, the efficacy and safety differ...
Revisiting CPSF30-mediated alternative polyadenylation in Arabidopsis thaliana
Alternative polyadenylation (APA) is an important contributor to the regulation of gene expression in plants. One subunit of the complex that cleaves and polyadenylates mRNAs in the nucleus, CPSF30 (f...
Enrichment of rare CFTR variants in Finnish patients with congenital chloride diarrhea
Objective The autosomal recessive disease congenital chloride diarrhea (CLD), caused by loss-of-function mutations in the solute carrier family 26 member 3 (SLC26A3) gene, shows association with infla...
Effectiveness of a school-based physical activity intervention on overweight and obesity among children and adolescents in Pakistan
Background Childhood obesity poses a significant public health challenge, yet effective school-based physical activity (PA) interventions remain scarce, especially in Pakistan. There is a lack of data...
Effects of neuromuscular versus stretching training performed during the warm-up on measures of physical fitness and mental well-being in highly-trained pubertal male soccer players
While there is ample evidence on the effects of neuromuscular training (NMT) and stretching training on selected measures of physical fitness in young athletes, less is known on the mental well-being...
Optimization of external container delivery and pickup scheduling based on appointment mechanism
Port transport efficiency has become an urgent issue that needs to be improved, especially the coordination among truck drivers during peak hours. Previous studies mainly focus on one-way container tr...
New horizons in live and dehydrated black soldier fly larvae usage: Behavioral and welfare implications in “Bianca di Saluzzo” cockerels
The literature on poultry welfare and behavior reports numerous promising effects derived from the administration of live or dehydrated black soldier fly larvae (BSFL) as environmental enrichment; how...
Research on the impact of COVID-19 on the financial system: Evidence from Indonesia
This study investigates the financial system vulnerability and pandemic impact on the financial system of Indonesia in 2015–2021. Two kinds of analysis are involved, i.e.: cross-section analysis at a...
A systematic review of automated hyperpartisan news detection
Hyperpartisan news consists of articles with strong biases that support specific political parties. The spread of such news increases polarization among readers, which threatens social unity and democ...
Influence of egg card color preference, inoculation time, generational succession, and learning experience on the parasitism of Trichogramma ostriniae
This study investigated the parasitic selection preferences of female Trichogramma ostriniae on egg cards of different colors, considering the effects of inoculation time, generations, and learning ex...
Ghana’s National Health Insurance enrollment: Does the intersection of educational and residential status matter?
Background Since its inception in 2003, Ghana’s Health Insurance Scheme (NHIS) has received considerable scholarly attention on the determinants of enrollment. While most of these studies highlight th...