PLoS ONE
Articles in this Issue
Tuberculosis screening, isoniazid preventive therapy coverage and factors associated with active TB diagnosis among people living with HIV at public health facilities of central Ethiopia
Introduction TB is the most frequent opportunistic infection and cause of death among People living with HIV/AIDS. Human immunodeficiency virus-positive individuals are routinely screened for tubercul...
Analysis of the fecal microbiome and metabolome in dairy cows with different body condition scores
Holstein Friesian is the most popular breed of dairy cows worldwide due to its exceptional milk production capabilities. In dairy cow management, the body condition score (BCS) is a useful tool, servi...
Morbillivirus and coronavirus survey in stranded cetaceans, Brazil
Since 2010, Guiana dolphin morbillivirus (GDMV; family Paramyxoviridae, genus Morbillivirus, species Morbillivirus ceti, syn. Cetacean morbillivirus) is recognized as the cause of death of multiple ce...
Lower termite (Coptotermes heimi) gut fibrolytic bacterial consortium: Isolation, phylogenetic characterization, fibre degradation potential and in vitro digestibility
Lower termites produce wide array of fibrolytic enzymes and serves as prospective microbial enzymes source for enhancing biodegradability of recalcitrant ligno-cellulosic fibrous feeds. The present st...
Analysis of cellular senescence-related genes in calcified aortic valve disease and the potential therapeutic role of β-Carotene
Objective Calcific aortic valve disease (CAVD) is a progressive, age-related degenerative disease characterized by the accumulation of calcium deposits in the aortic valve. We aim to screen key genes...
Role of vitamins in the pathogenesis and treatment of restless leg syndrome: A systematic review and meta-analysis
We performed a meta-analysis to assess the role of vitamins in the possible pathogenesis and treatment of RLS (Restless Leg Syndrome). A systematic search of the PubMed, Cochrane, Embase, and Web of S...
Screening and identification of strains for high quality and antioxidant activity of Baijiu from strong-flavor Daqu and analysis of microbial synergistic effects
In this study, functional strains with strong fermentation characteristics were isolated from Strong-flavor Daqu and evaluated for their ability to enhance the quality and antioxidant activity of Baij...
Sex differences in the risk profiles for anemia in people living with HIV, A cross sectional study
Background Anemia in people living with HIV (PLWH) significantly impacts quality of life and health outcomes. This study aimed to determine sex differences in factors associated with anemia in PLWH a...
Phenotypic plasticity of bread wheat contributes to yield reliability under heat and drought stress
Yield reliability under diverse environments is important to address climate stress consequences in wheat production systems. Breeding for reliability under a changing climate remains a challenge in w...
Developing a competency assessment framework for pharmacists in primary health care settings in India
Background Competency frameworks in the pharmacy profession define the necessary practice standards and establish benchmarks for work accountability and career progression. Pharmacists are integral to...
Change in address in electronic health records as an early marker of homelessness
Introduction Housing stability is a key health determinant and there is a need for early screening for instability with existing electronic health record (EHR) data to improve health outcomes. We aim...
Effect of Nordic walking on walking ability in patients with peripheral arterial disease: a meta-analysis
Background Evaluating the effectiveness of Nordic walking in influencing walking ability in patients with peripheral arterial disease. Methods We searched 12 databases, including PubMed, Embase, Coc...
Inbred rat heredity and sex affect oral oxycodone self-administration and augmented intake in long sessions: correlations with anxiety and novelty-seeking
Oxycodone abuse frequently begins with prescription oral oxycodone, yet vulnerability factors (e.g. sex, genetics) determining abuse are largely undefined. We evaluated genetic vulnerability in a rat...
Development of a multi-epitope vaccine against Acinetobacter baumannii: A comprehensive approach to combating antimicrobial resistance
Background The World Health Organization has categorized Acinetobacter baumannii (A. baumannii) as a critical priority pathogen due to its high antibiotic resistance. This resistance complicates trea...
Reciprocal regulation between Acinetobacter baumannii and Enterobacter cloacae AdeR homologs: implications for antimicrobial resistance and pathogenesis
Acinetobacter baumannii and Enterobacter cloacae are phylogenetically distant Gram−negative bacterial pathogens that represent significant challenges in healthcare settings due to their remarkable abi...
Correction: (−)-Epicatechin regulates endoplasmic reticulum stress and promotes ferroptosis in lung cancer cells via the PERK/eIF2α/ATF4 signaling pathway
Factors associated with uptake of human papilloma virus vaccine among adolescent girls: A cross sectional survey on insights into HPV Infection Prevention in Kabarole District, Western Uganda
Background Human papilloma virus (HPV) infection imposes a substantial global disease burden and represents a critical public health concern. The persistently low uptake of HPV vaccination poses a sig...
Correction: On escape criterion of an orbit with s−convexity and illustrations of the behavior shifts in Mandelbrot and Julia set fractals
A verifiably secure and robust authentication protocol for synergistically-assisted IoD deployment drones
Drones have limited computing and storage resources, which makes them unable to perform complex tactical tasks; drones working in clusters can be employed for such complex tactical task completion. Bu...
Genomic insights into Mediterranean pepper diversity using ddRADSeq
This work investigated the genetic diversity and population structure of 99 pepper lines (Capsicum annuum L.), acclimated to Mediterranean climate conditions, using double-digest restriction site-asso...
Multimodal prehabilitation in people awaiting acute inpatient cardiac surgery: Study protocol for a pilot feasibility trial (PreP-ACe)
Background The concept of “prehabilitation,” or optimising individual physical and mental wellbeing prior to surgery is well established in cancer and orthopaedic populations. Howe...
Digitalizing the community health information system improved women’s retention on the maternal continuum of care pathway in northwest Ethiopia: A quasi-experimental study
Background Retaining women on the maternal continuum of care pathway remains a significant challenge for the healthcare system. Digitalizing primary healthcare system using community health workers i...
Effects and functional mechanisms of digital fitness platforms on online fitness payment behavior under the perspective of “She-economy”
Women have become an important force for economic development. Online fitness payment behavior is an important part of women’s pursuit of “beautiful skin and healthy body”, and is also an important em...
Kaempferia parviflora extract and its methoxyflavones as potential anti-Alzheimer assessing in vitro, integrated computational approach, and in vivo impact on behaviour in scopolamine-induced amnesic mice
Alzheimer’s disease (AD), a growing global challenge, lacks effective preventive and therapeutic strategies. This study explored the promising potential of the Kaempferia parviflora (KP) and its metho...
The impact of digital transformation on open innovation performance: The intermediary role of digital innovation dynamic capability
In the context of digital economy, both the process and boundaries of open innovation performance are changing, and digital transformation has become an important factor for enterprises to realize ope...