PLoS ONE
Articles in this Issue
Spatiotemporal changes in river network connectivity in the Nile River Basin due to hydropower dams
Dams offer indispensable services, including hydropower generation, water for irrigation, and flood mitigation. These barriers disrupt natural river flows, affecting river ecosystems structural and fu...
Makerspace network embeddedness, business model innovation, and user entrepreneurial performance in China: The moderating effect of environmental dynamics
Makerspaces gather a large number of entrepreneurial entities and resources, playing a vital role in the survival and development of user entrepreneurial enterprises. Based on network embeddedness the...
Spatial distribution and determinants of micronutrient intake status among children aged 6–23 months in Ethiopia: A Multi-scale Geographical Weighted Regression Analysis
Introduction Micronutrient (MN) deficiency is a major global health concern, especially in developing countries like Ethiopia. However, there is a lack of comprehensive monitoring and information rega...
Digital inclusive finance penetration and household debt maturity structure: Empirical estimation based on China Family Panel Studies Data
This paper analyzes how the penetration of digital inclusive finance affects the maturity structure of household debt by matching data from the Peking University Digital Inclusive Finance Index and Ch...
A modified rat model of 8 minutes asphyxial cardiac arrest and cardiopulmonary resuscitation
The animal model of cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) serves as a crucial tool for investigating the pathophysiology and treatment strategies associated with cardiac arrest,...
An internet-delivered psychoeducational intervention (Fex-Can 2.0) targeting fertility-related distress and sexual dysfunction in young adults diagnosed with cancer: Study protocol of a randomized controlled trial with an internal pilot phase
Background While previous literature has continuously demonstrated the negative effects of cancer and its treatment on fertility and sexuality, evidence-based interventions to alleviate fertility-rela...
Effects of plyometric training on jump, sprint, and change of direction performance in adolescent soccer player: A systematic review with meta-analysis
Background Soccer requires a high level of physical fitness, particularly in jumping, sprinting, and change-of-direction (COD) performance. Plyometric training has been extensively studied in adult at...
Higher accumulation of mitragynine in Mitragyna speciosa (kratom) leaves affected by insect attack
Kratom leaves are widely consumed by locals to increase their stamina for working longer hours in the field. However, insect damage to the leaves can lead to significant loss of leaf harvest. Despite...
Energy price instability and energy efficiency: Korea’s macroeconomic framework during the COVID-19 pandemic
The pervasive effects of the COVID-19 pandemic in Korea on the daily lives of Korean citizens, as well as the nation’s economic and industrial landscape, cannot be understated. In this article, we exp...
Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies
Gene expression profiling plays a crucial role in understanding the role of Krüppel-like factor 4 (KLF4) in the prognosis and tumor immune microenvironment of various malignancies. The transcription f...
Contextual challenges and impacts on the surgical ecosystem in Chiapas, Mexico: A qualitative study
Chiapas is a state in southern Mexico that faces significant challenges in healthcare delivery. Strengthening the surgical system requires a comprehensive understanding of all health system domains an...
Internal iteration gradient estimator based parameter identification for nonlinear sandwich system subject to quantized sensor and friction nonlinearity
This study proposes an internal iteration scalar-innovation gradient estimation method based on multi-innovation theory for a nonlinear sandwich system subject to a quantized sensor and friction nonli...
Using artificial intelligence-based software for an unbiased discrimination of immune cell subtypes in the fracture hematoma and bone marrow of non-osteoporotic and osteoporotic mice
It is well established that the early inflammatory response following fracture is essential for initiating subsequent bone regeneration. An imbalance in inflammation, whether within the innate or adap...
The role of photobiomodulation in the functional recovery of proximal humerus fractures: a randomized controlled clinical protocol
Pain and joint stiffness contribute to functional limitation in the postoperative period following proximal humeral fractures (PHF). Photobiomodulation (PBM) has demonstrated positive outcomes in frac...
Mental health of persons with disabilities during the COVID-19 pandemic in Bangladesh
Background The COVID-19 pandemic has impacted the mental health of people across the world, including those with disabilities in Bangladesh. However, very little research exists that has explored the...
Integrated bulk RNA and single-cell analysis with experimental validation reveal oxidative stress-related diagnostic biomarkers for osteoporosis
Osteoporosis (OP) is a systemic skeletal disorder characterized by reduced bone mass and deterioration of bone microarchitecture, which increases fracture risk and impairs physical function. This stud...
Food safety practices of individuals before and after the emergence of COVID-19: A pre- and post-comparative analysis
Background Recent literature highlights both beneficial and adverse effects of COVID-19 on individual food safety practices; however, the actual impact remains unverified, especially in low-resource c...
End-of-life care in hematological malignancies – a nationwide comparative study on the Swedish Register of Palliative Care
Background Patients with hematological malignancies are less likely to be referred to specialized palliative care, and more likely to receive aggressive end-of-life care than patie...
Analysis of extraocular muscle volumes in idiopathic hypertrophic pachymeningitis patients
Background Idiopathic hypertrophic pachymeningitis (HP) is a rare chronic inflammatory condition without an identifiable cause characterized by fibrous thickening of the dura mater...
Betaine supplementation affects carbohydrate metabolism in the skeletal muscle of finishing pigs
This study aimed to assess the effect of betaine supplementation on the proteomic profile of the longissimus thoracis muscle in finishing pigs. Thirty-six crossbred female pigs (initial body weight =...
Standardized methods for rearing a moth larva, Manduca sexta, in a laboratory setting
The larval tobacco hornworm, Manduca sexta , has been used in a laboratory setting for physiological studies and for pathogen virulence studies. This moth offer...
Research on real-world emission characteristics based on the Symmetry Solid SCR system
In the actual use process, especially under the low exhaust temperature in urban conditions, the actual NOx emission of diesel engines using the Urea SCR technology is higher than expected, which seri...
Clinical and safety outcomes in unresectable, very early and early-stage hepatocellular carcinoma following Irreversible Electroporation (IRE) and Transarterial Chemoembolization (TACE): A systematic literature review and meta-analysis
Background Locoregional treatments for early-stage unresectable hepatocellular carcinoma (HCC) are widely used, with irreversible electroporation (IRE) and transarterial chemoembolization (TACE) repre...
Emergency department is not safe anymore: Nurses describing their suffering
Background Workplace violence represents a critical and alarming crisis in healthcare settings around the globe. This study seeks to shed light on the experiences of Jordanian nurses working in emerge...
Lifestyle, nutritional, and health influences on consumption of artificially-sweetened beverages in educated urban populations
Objectives This study analysed the prevalence of artificially-sweetened beverages (ASB) consumption in the Thai population, and examined associations between ASB consumption and lifestyle, and nutriti...