PLoS ONE
Articles in this Issue
Improving China’s maritime law enforcement operations against overfishing in the South China Sea—Based on a comparison with the Indonesian law enforcement system against IUU Fishing
Overfishing in the South China Sea has become increasingly severe these years, with Illegal, Unreported, and Unregulated (IUU) fishing being one of the main contributors to this problem. To ensure reg...
Informal workers’ perceptions of retirement planning in developing countries
In this study, we examine the perceptions of informal workers toward retirement planning in developing countries. Specifically, we examine vegetable market vendors’ perceptions of the local superannua...
The role of ANGPTL4 in cancer: A meta-analysis of observational studies and multi-omics investigation
Background Angiopoietin-like protein 4 (ANGPTL4) plays a crucial role in processes such as angiogenesis, inflammation, and metabolism. Despite numerous studies suggesting its involvement in cancer, a...
Retraction: Gulf war illness inflammation reduction trial: A phase 2 randomized controlled trial of low-dose prednisone chronotherapy, effects on health-related quality of life
A novel gastric ulcer model in rats using filter paper with acetic acid
Gastric ulcer animal models are essential for research, but conventional acetic acid-based methods are limited by technical complexity, prolonged modeling duration, and poor applicability for solid an...
Time-to-recovery from severe pneumonia and its predictors among children 2–59 months of age admitted to the pediatric ward of Jimma University Medical Center, Southwest Ethiopia, 2023: A retrospective cohort study
Background Pneumonia is an inflammation of lung parenchyma. The World Health Organization estimated 156 million cases of pneumonia occur annually. Out of them, 20 million cases severe enough to requir...
The relationship between physical function and psychological symptoms in Parkinson’s: Perceptions of People with Parkinson’s and Carers
Background People with Parkinson’s (PwP) can experience both physical and psychological symptoms, and understanding the perspectives of people affected is crucial for improved management, and clinical...
Assessment of community knowledge on non-communicable diseases to inform the pilot of WHO PEN-Plus initiatives in selected two districts in Tanzania
Background Non-communicable diseases (NCDs) have increased significantly in Tanzania, accounting for 33% of mortality in the country. Having adequate knowledge translated into practice has a significa...
Multi-scale prototype convolutional network for few-shot semantic segmentation
Few-shot semantic segmentation aims to accurately segment objects from a limited amount of annotated data, a task complicated by intra-class variations and prototype representation challenges. To addr...
Investigating the application of IoT mobile app and healthcare services for diabetic elderly: A systematic review
As the prevalence of diabetes increases among the elderly population, effective management becomes increasingly crucial. IoT mobile applications offer promising solutions for diabetes care by providin...
Functional kinome profiling reveals brain protein kinase signaling pathways and gene networks altered by acute voluntary exercise in rats
Regular exercise confers numerous physical and mental health benefits, yet individual variability in exercise participation and outcomes is still poorly understood. Uncovering the neurobiological mech...
Trop-2 expression in non–small cell lung cancer
Trophoblast cell-surface antigen 2 (Trop-2) is highly expressed in non–small cell lung cancer (NSCLC) and has become an attractive target for antibody-drug conjugates (ADCs). ADC tumor target expressi...
Creating a novel algorithm for studying the strong convergence to a sequence with applications
This manuscript introduces a novel algorithm tailored to investigate the strong convergence of sequences under specific conditions. Notably, the framework incorporates a finite family of generalized d...
Predicting diabetes mellitus metabolic goals and chronic complications transitions—analysis based on natural language processing and machine learning models
Objective To estimate Diabetes mellitus (DM) progression at one and two years in terms of glycemic targets and development of complications. Research design and methods We analyzed a retrospective c...
Assessing the feasibility of large language models to identify top research priorities in enhanced external counterpulsation
Enhanced External Counterpulsation (EECP), as a non-invasive, cost-effective, and efficient adjunctive circulatory technique, has been widely applied in in the cardiovascular field. Numerous studies a...
Knee and hip osteoarthritis increase the risk of cardiovascular disease: A national registry-based longitudinal cohort study
Objective Osteoarthritis and cardiovascular disease are major public health challenges. We aimed to estimate the average sex-specific effects of knee and hip osteoarthritis on the risk of cardiovascul...
Experiences of immigrants when accessing mental health services and psychosocial supports in Canada: Protocol for a scoping review
In Canada, the mental health needs of immigrants from diverse ethnic backgrounds are a growing concern, as they are at a higher risk for adverse mental health outcomes compared to native-born Canadian...
Effect of knowledge of sulfadoxine-pyrimethamine (SP) as prophylaxis for malaria on its uptake for intermittent preventive treatment of malaria in pregnancy (IPTp): Application of inverse probability weighted regression adjustment (IPWRA) technique
Introduction Malaria still remains a global health issue. In response, the World Health Organisation has continuously recommended the use of Sulfadoxine-Pyrimethamine (SP) for Intermittent Preventive...
Prevalence and factors associated with Helicobacter Pylori infection among patients with dyspeptic symptoms in Tanzania: Experience from temeke regional referral hospital in Dar Es Salaam
Introduction Helicobacter pylori is a type of bacteria that infects the stomach lining and can cause various gastrointestinal disorders, such as dyspepsia, gastritis and peptic ulcers. Dyspepsia is a...
Clinical feature and gene expression analysis in low prostate-specific antigen, high-grade prostate cancer
Background Prostate cancer (PCa) patients with low prostate-specific antigen (PSA) levels can occasionally present high-grade disease. These patients often exhibit resistance to androgen deprivation t...
Simulation of layered soil water transport in the semi-arid region based on Hydrus-3D
This study addresses the unclear water transport patterns in reconstructed layered soils in the arid and semi-arid climate zones of northwestern China by utilizing the Hydrus-3D model to simulate the...
Translation and validation of the Chinese version of EORTC QLQ-SWB32 assessing the spiritual wellbeing of women with gynecological cancer
Background This study aimed to translate the internationally developed and validated European Organization for Research and Treatment of Cancer measure of spiritual wellbeing (EORTC QLQ-SWB32) into Ch...
Discrepancies at clinical presentation of patients with soft tissue sarcoma according to the type of health insurance in a Brazilian population
Background In Brazil, 75% of the population is covered by public health insurance (PubHIn), and the rest pay for private insurance (PrivHIn). The impact of the type of health insurance on clinical pre...
The Chagas non-endemic (ChaNoE) cohort: Aims and study protocol
Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical disease with significant public health implications. While its primary transmission occurs in endemic regions via triatomine v...
The burden of HIV/AIDS in Ethiopia: Unveiling 30 years of trends in incidence, mortality, and disability—insights from the Global Burden of Disease study (1990–2021)
Background Over the past three decades, Ethiopia has witnessed a dynamic shift in the burden of HIV/AIDS, a public health crisis that has profoundly impacted communities nationwide. While significant...