PLoS ONE
Articles in this Issue
Long-term outcomes after revascularization surgery for adult moyamoya disease: Protocol for systematic review and meta-analysis
Introduction Moyamoya disease (MMD) commonly presents with cerebral ischemia or hemorrhage. Revascularization surgery, including direct, indirect, and combined bypasses, remains the mainstay of MMD tr...
Cluster randomized controlled trial to assess the effectiveness of a package of community-based interventions on continuum of maternal and newborn healthcare in Sidama, Ethiopia: The SiMaNeH trial protocol
Background Maternal and newborn mortality and morbidity remain high in low- and middle-income countries such as Ethiopia. Limited access and dropouts from essential continuum of ca...
The impact of policy incentives and value perception on rural residents’ clean heating behavior: Evidence from northern China
Implementing energy transition in rural areas is crucial for China to achieve its low-carbon transition in energy consumption and dual-carbon goals. This study aimed to elucidate policy effects and fu...
Modeling lifetime and count data using a unified flexible family: Its discrete counterpart, properties, and inference
In this article, two flexible classes called the modified Kavya–Manoharan-G (MKM-G) and discrete modified Kavya–Manoharan-G (DMKM-G) families are investigated. The two proposed families provide more f...
Exploring mobility patterns and social health of older Canadians living at home to inform decision aids about housing: A mixed-methods study
Introduction Many tools support housing decisions for older adults but often overlook mobility patterns and social health. We explored these factors in older Canadians living at home to inform housing...
Job satisfaction mediates the effect of self-efficacy on work engagement among physical education teachers in economically disadvantaged areas
The unequal distribution of educational resources across regions with varying levels of socioeconomic development remains a global issue. Teachers in economically disadvantaged areas often exhibit low...
Impact of diabetes mellitus on 30-day mortality among acute stroke patients in northern Tanzania
Background Among acute stroke patients (ASPs), diabetes mellitus (DM) is associated with a higher risk of death, functional dependency, and recurrence. This study aimed to determine the impact of DM o...
Protocol to evaluate the effectiveness of the implementation of transdiagnostic cognitive behavioural therapy for emotional disorders in primary care and its mechanisms of change: a randomized step-wedge clinical trial (PsicAP-CV)
Introduction Emotional disorders (ED) are highly prevalent worldwide. The PsicAP trial, conducted in Spain, demonstrated the benefits of adding transdiagnostic cognitive behavioural therapy (TD-CBT) t...
CFD based design optimization of dimples induced on Blended Wing Body airframe using the Taguchi method
This research focuses on optimizing the design of dimples on a Blended-Wing-Body (BWB) airframe to enhance aerodynamic efficiency. Dimples serve as a passive flow control method intended to improve ae...
Urdu adaptation and validation of a disease-specific quality-of-life questionnaire in a Pakistani population of Achalasia
Background Achalasia, a rare esophageal disease marked by dysphagia, impacts health-related quality-of-life (HRQoL), measurable by disease-specific tools like achalasia-specific questionnaire (ASQ) th...
Identification of visible and near-infrared signature peaks for arboviruses and Plasmodium falciparum
Arbovirus and malaria infections affect more than half of the world’s population causing major financial and physical burden. Current diagnostic tools such as microscopy, molecular and serological tec...
CT features and histogram analysis of non-contrast images for differentiating malignant and benign mediastinal lymph nodes in Non-Small Cell Lung Cancer (NSCLC)
Objective To evaluate the diagnostic value of CT features and histogram analysis in distinguishing between malignant and benign mediastinal lymph nodes in patients with non-small cell lung cancer (NSC...
Breastfeeding transition in Oman: A generation shift or a product of social development? A qualitative study on three generations of Omani mothers
Background Exclusive breastfeeding is essential for infant health, yet its practice varies across generations and cultures. Although the health benefits of breastfeeding have been well known for decad...
Transcriptome and network analysis pinpoint ABA and plastid ribosomal proteins as main contributors to salinity tolerance in the rice variety, CSR28
Salinity stress is a major challenge for rice production, especially at seedling stage. To gain comprehensive insight into the molecular mechanisms and potential candidate genes involved in rice salin...
Burden of Chronic obstructive pulmonary disease in China: an analysis based on the GBD 2021 compared with the United States
Background Chronic obstructive pulmonary disease is an important disease affecting physical health worldwide, and the burden of this disease has been growing since 1991 for both China and the US. Ob...
Anticancer properties of peptides and protein hydrolysates derived from Asian water monitor (Varanus salvator) serum
This study investigated the anticancer efficacy of <3 kDa fractions derived from native peptides and protein hydrolysate of Varanus saltator serum. The inhibitory effects of these fractions were ev...
“Everyone says ‘safe sex’ but no one ever says ‘safe drugs’, you know?”: Perspectives on the intersection of drug checking services, drug policy and the overdose crisis
Background Overdose deaths have continued to rise in the US despite heightened public attention and resources. Drug checking shows promise for integration into existing services for people who use dru...
High impedance faults detection in power distribution networks using rogowski coils, kalman filtering, least-squares and non-recursive DFT computation engines
This paper presents a novel computational engine based on non-recursive discrete Fourier transform (DFT) technology to detect high-resistance faults (HRFs) in power distribution networks. The non-recu...
How do positive and negative emotions influence children’s and adolescents’ arithmetic performance?
This study is the first to investigate how negative and positive emotional states influence children’s arithmetic performance and age-related differences therein. Children aged 8–14 (n = 149) were ask...
Scaling-basis chirplet extracting transform and its application in bearing fault diagnosis
In this paper, we propose a new time-frequency analysis (TFA) method, namely scaling-basis chirplet extracting transform (SBCET). Based on the time-frequency representation (TFR) results obtained by s...
Design and development of an irrigation monitoring and control system based on blynk internet of things and thingspeak
The scarcity of water resources exacerbated by climate change poses a major challenge for sustainable agriculture. This study presents an Internet of Things (IoT)-enabled irrigation system designed fo...
Outdoor recreation’s association with mental health and well-being during the COVID-19 pandemic
Outdoor recreation provided a crucial way to maintain physical activity, reduce stress, and preserve a sense of normalcy during the COVID-19 pandemic. This study assessed the relationship between outd...
Quantitative risk assessment and interventional recommendations for preventing canine distemper virus infection in captive tigers at selected wildlife stations in Thailand
Canine distemper virus (CDV) can cause high morbidity and mortality in large felids and pose a significant threat to the conservation of captive and non-captive tiger (Panthera tigris). This study con...
Resveratrol decreases extracellular traps (ETs) in acute promyelocytic leukemia (NB4) cells
Background Activated neutrophils can create structures known as neutrophil extracellular traps (NETs/ETs) consisting of nuclear components and granules. The ETOsis phenomenon leads to activating the p...
Improved performance of fNIRS-BCI by stacking of deep learning-derived frequency domain features
The functional near-infrared spectroscopy-based brain-computer interface (fNIRS-BCI) systems recognize patterns in brain signals and generate control commands, thereby enabling individuals with motor...