PLoS ONE
Articles in this Issue
Empowering entity synonym set generation using flexible perceptual field and multi-layer contextual information
Automatic generation of entity synonyms plays a pivotal role in various natural language processing applications, such as search engines, question-answering systems, and taxonomy construction. Previou...
A study on monthly sales forecasting of new energy vehicles in urban areas using the WOA-BiGRU model
To accurately predict the sales of new energy vehicles (NEVs) in Chinese cities and explore the applicability of optimization algorithms for GRU models in forecasting urban NEV sales., this paper cond...
Impact of climate on water status, growth, yield, and phenology of coffee (Coffea arabica) plants in the central region of the state of Veracruz, Mexico
Coffee (Coffea arabica) is one of the most widely traded and most consumed agro-products worldwide. Its production is concentrated in tropical regions, and its consumption, in northern countries. Clim...
Factors predicting parenting stress in the autism spectrum disorder context: A network analysis approach
Elevated levels of parenting stress have been reported in parents raising an Autistic child. Previous studies have identified a multitude of predictors of parenting stress, including both child-relate...
Effects of tape and Kinesiotape on ankle range of motion, Single Leg Drop Jump and balance after running-induced fatigue: a cross-over clinical trial
The prevention and management of injuries in runners is a key area of research in sports medicine. Fatigue during running can lead to biomechanical imbalances and inhibition of stabilizing muscles, in...
Fetal macrosomia and its associated factors among pregnant women delivered at national referral hospital in Uganda, a case-control study
Background The delivery of macrosomic newborns (newborns>4000gm) is increasing steadily worldwide and yet it is associated with many complications. The risk factors for fetal ma...
The proprioceptive puzzle: An observational study investigating the effects of cervical proprioceptive errors on quantitative sensory testing and body awareness in young individuals
Objective The present study investigates the effects of cervical proprioceptive errors (CPE) on body awareness and quantitative sensory testing (QST), including the pressure pain threshold, temporal s...
Estimating oxygen uptake in simulated team sports using machine learning models and wearable sensor data: A pilot study
Accurate assessment of training status in team sports is crucial for optimising performance and reducing injury risk. This pilot study investigates the feasibility of using machine learning (ML) model...
Effects of step width and gait speed on the variability of mediolateral control in the head and trunk during gait
Step width is a parameter that determines the size of the base of support (BOS) during gait. Further, it is related to the control of center of mass (COM) and trunk movements and gait speed. The curre...
Acceptability of broadly neutralizing antibodies (bNAbs) for HIV prevention among vulnerable populations in India: Findings from a qualitative study
With newer advances in HIV biomedical research, the prevention toolbox is expanding with potential inclusion of long-acting anti-retrovirals, broadly neutralizing antibodies (bNAbs), and vaccines. Whi...
Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research
Whole transcriptome sequencing (WTS/ RNA-Seq) is a ubiquitous tool for investigating cancer biology. RNA isolated from frozen sources limits possible studies for analysis of associations with phenotyp...
Separated or joint models of repeated multivariate data to estimate individuals’ disease trajectories with application to scleroderma
Estimating a patient’s disease trajectory as defined by clinical measures is an essential task in medicine. Given multiple biomarkers, there is a practical choice of whether to estimate the joint dist...
Capecitabine metronomic chemotherapy for metastatic colorectal cancer patients reaching NED: A protocol for a prospective, randomized, controlled trial
Introduction An increasing number of patients with metastatic colorectal cancer (mCRC) have achieved no evidence of diseases (NED) status after surgery or other treatments. However, the latest guideli...
Cognitive functional therapy versus therapeutic exercises for the treatment of individuals with chronic shoulder pain: A protocol for a randomized controlled trial
Introduction Shoulder pain is a debilitating musculoskeletal condition with functional, physical, and psychological impacts. Interventions for chronic shoulder pain should address the biopsychosocial...
Association of mean corpuscular volume with 28-day mortality in sepsis patients: A retrospective cohort study using eICU data
Introduction The issue of mortality due to sepsis remains a significant concern in the field of medicine. Previous researches have demonstrated an association between mean corpuscular volume (MCV) and...
Thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, and biotin hard gelatin capsules prepared in advance and stored for the treatment of pediatric metabolic diseases: a safer alternative
The treatment of several pediatric metabolic diseases involves vitamins supplementation. Among these, thiamine, riboflavin, pyridoxine and biotin can be prescribed and compounded as hard gelatin capsu...
Confidence interval forecasting model of small watershed flood based on compound recurrent neural networks and Bayesian
Flood forecasting exhibits rapid fluctuations, water level forecasting shows great uncertainty and inaccuracy in small watersheds, and the reliability and accuracy performance of traditional probabili...
Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies
Background Sickle cell anemia (SCA) rank 11th among all causes of mortality in Sub-Saharan Africa, with the region accounting for 75% of global cases. Inconsistent diagnostic methods and country-speci...
The impact of long-term care insurance on household expenditures of the elderly: Evidence from China
This study aims to investigate the impact of China’s long-term care insurance (LTCI) pilot on household expenditures of the elderly. Utilizing the China Health and Retirement Longitudinal Study (CHARL...
Effect of match load on perceived wellness in highly trained female football players
Background Exposure to match loads significantly affects physiological and psychological indicators and, consequently, players’ wellness. However, this information is still scarce in women’s football....
Trunk rotation, spinal deformity and appearance, health-related quality of life, and treatment adherence: Secondary outcomes in a randomized controlled trial on conservative treatment for adolescent idiopathic scoliosis
Objective To explore secondary outcomes at endpoint comparing treatments with adequate self-mediated physical activity combined with either night-time brace (NB), scoliosis-specific exercise (SSE), or...
Elucidating the structural dynamics induced by active site mutations in 3C protease of foot-and-mouth disease virus
The viral replication of foot-and-mouth disease virus (FMDV) and other picornaviruses primarily depends on the successful processing of a polyprotein precursor by the enzyme 3C protease (3Cpro) at spe...
Cost-utility analysis of botulinum toxin type A versus oral drug treatment in patients with severe blepharospasm in Thailand
Background Blepharospasm is a chronic facial movement disorder affecting a person’s ability to work, causing depression, pain, and a reduced quality of life (QoL). Botulinum toxin type A (BoNT-A) trea...
Dynamical analysis of scabies delayed epidemic model with second-order global stability
Scabies is a highly transmitted skin disease that can affect people of all ages, especially children. According to the World Health Organization (WHO), South Asia and sub-Saharan Africa are the region...
TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cells
Wound healing involves the collaboration of multiple cells, including macrophages and fibroblasts, and requires the coordination of cytokines, growth factors, and matrix proteins to regulate the repai...