PLoS ONE
Articles in this Issue
University students’ self-assessment of data literacy: A validation study
As data literacy has emerged as a critical skill for professionals across industries, educators in higher education have incorporated it into their curricula and instruction. Understanding and evaluat...
Spatiotemporal dynamics of visitors to Jeju Island: Hotspot and spatial autocorrelation analyses using mobile phone data
This study used mobile phone data to examine the spatiotemporal patterns and preferences of domestic visitors to Jeju Island, South Korea and integrated hourly floating population data to examine visi...
Hospitalization dynamics during COVID-19: Insights into disease trends and patient outcomes
Objectives To find the pattern of hospitalization pattern change in COVID-19 pandemic, we aimed to compare the admission and mortality rate of each disease in all wards before and during the pandemic....
Study protocol for an observational research study with an embedded N-of-1 design: Increasing the availability of goal-oriented cognitive rehabilitation for people living with dementia in Ireland
Background Goal-Oriented Cognitive Rehabilitation (GREAT-CR) is an evidence-based early intervention for people with mild-moderate dementia that improves goal attainment and functional outcomes. In Ir...
Cryptic biodiversity of freshwater fish species in Bangladesh
Unrecognized cryptic species impede conservation planning and biodiversity assessments. DNA barcoding has tremendously expanded the number of novel and cryptic species in biological science. Despite f...
Association between midday napping and long-term trajectories of cognitive function among middle-aged and older Chinese adults
Background The prevalence of dementia has become an increasingly important public health priority. This study investigated the association between midday napping and long-term trajectories of cognitiv...
Association between primary care physicians’ practice models and referral rates to specialists: A sex-based cross-sectional study
Referrals from primary care physicians (PCPs) to specialists are a key function of the primary care system, enabling access to secondary and tertiary health care services. Since the early 2000s, Ontar...
Socioeconomic inequalities of 3-year survival in formal employees with colorectal cancer between 2012 and 2019 in Colombia
Background Colorectal cancer is a high-burden disease that requires comprehensive multidisciplinary management. In Colombia, despite a healthcare system covering 97% of the populat...
Revisiting the cognitive and behavioral aspects of loneliness: Insights from different measurement approaches
Loneliness is increasingly recognized as a critical public health issue that profoundly affects psychological well-being and social functioning. This study evaluates cognitive and behavioral differenc...
Comparison of absorption and excretion of test compounds in sucking versus chewing pests
A critical understanding of how pests interact with active ingredients is essential for the development of new insect control solutions to maintain crop quality and quantity by reducing insect damage....
The first validation of the Functional Assessment of Cancer Therapy Hepatobiliary (FACT-Hep) for evaluating health-related quality of life (HRQOL) in patients with advanced-stage intrahepatic cholangiocarcinoma (biliary tract cancer)
Background The FACT-Hep questionnaire has been used to evaluate the health-related quality of life (HRQOL) in various types of hepatobiliary cancer. Nevertheless, the application in intrahepatic chola...
Potential drug targets for Neuromyelitis optica spectrum disorders (NMOSD): A Mendelian randomization analysis
Background Certain peripheral proteins are involved in the development of Neuromyelitis optica spectrum disorders (NMOSD), such as IL-6, complement proteins, and MHC class II molecules. However, the r...
Expression of Concern: General sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC
A hybrid power load forecasting model using BiStacking and TCN-GRU
Accurate power load forecasting helps reduce energy waste and improve grid stability. This paper proposes a hybrid forecasting model, BiStacking+TCN-GRU, which leverages both ensemble learning and dee...
Cross-cultural adaptation and psychometric evaluation of the urdu version of the morisky, greene, and levine medication adherence scale (MGLS-4) for major depressive disorder patients
In Pakistan, Major depressive disorder (MDD) contributes significantly to the mental health burden. It is crucial to understand patients’ medication adherence status for developing a strategy for impr...
Risk factors for hypotony after transconjunctival sutureless vitrectomy
Purpose To identify risk factors for unexpected hypotony after transconjunctival sutureless vitrectomy (TSV). Methods In this retrospective observational study, we defined postoperative hypotony as...
Eco-products value realization and eco-industry design of afforestation in the Karst Desertification Control
Karst desertification (KD) severely restricts rural development in China’s karst regions. To ensure both ecological security and economic sustainability, afforestation is essential for karst desertifi...
Optimizing CMV therapy: Population pharmacokinetics and Monte Carlo simulations for letermovir and maribavir dosage
Purpose This study seeks to reassess and enhance the dosing strategies of letermovir and maribavir for treating cytomegalovirus (CMV) infection, aiming to propose adjustments that could improve therap...
How does the farmland management rights mortgage loan affect food security: Based on the evidence of major grain producing areas in China
The people are the foundation of the nation, and grain is vital for their survival. Food security is crucial for national stability and well-being. This study utilizes panel data from 1,234 counties i...
Axial compression behavior and failure mechanism of CFRP-confined circular hollow steel tube short columns: Theoretical and numerical analysis
Circular hollow steel tubes (CHST) are widely employed as short columns in various infrastructure applications. This study comprehensively investigates the mechanical behavior of CFRP-Confined CHST (C...
Evaluating the effectiveness of speed humps and rumble strips in improving pedestrian safety in Addis Ababa, Ethiopia
Pedestrian fatalities remain a major road safety problem in Addis Ababa. To address this problem, speed humps and rumble strips were introduced on high-crash road segments in the city in 2017. As a ca...
Are you with me? Co-occurrence tests from community ecology can identify positive and negative epistasis between inversions in Mimulus guttatus
Chromosomal inversions are structural genetic variants that can play a crucial role in adaptive evolution and speciation. Patterns of attraction and repulsion among unlinked inversions — whether they...
Psycho-oncology practice for cancer patients during the pandemic lockdown in Italy: A qualitative mixed-method study with psychotherapists
Background At the beginning of the COVID-19 outbreak, psychotherapy practice underwent a drastic reorganization. To enhance knowledge of the challenges healthcare professionals faced during the pandem...
Research on the performance of phase change energy storage devices based on solar energy
This article designs a high-altitude border guard post that can fully utilize the heat absorbed by solar collectors to continuously store thermal energy during the day and stably release heat at night...
Prevalence, risk and protective factors of burnout among Korean hospitalists
Background Burnout among healthcare professionals is a critical factor which affects patient safety, treatment outcomes, and the quality of care. This is especially important for hospitalists who mana...