PLoS ONE
Articles in this Issue
Effect of weekly Plyometric training frequency on Adolescents female basketball players during in-season: A comparison of two vs. four sessions
This study investigated the effects lower vs. higher frequencies of volume-equated plyometric training youth female basketball players. Thirty youth highly trained female basketball players (age, 15.7...
Prevalence of multimorbidity and its relationship with socioeconomic status among Chinese older adults over time
Previous studies linking socioeconomic status (SES) to chronic diseases tended to focus on a single disease. As people age, they are more likely to suffer from multiple coexisting chronic conditions,...
Individual action, sharing scarce resources, sharing information? A study on how to effectively manage forest pests and diseases based on carbon trading
In recent years, forest pests and diseases have had a significant impact on forest ecosystems. To incentivize corporations to manage forest pests and diseases, the government provides certain carbon c...
Status and related factors of medication safety behaviour of nurses in the operating room: A cross-sectional survey in China
Aim This study aimed to investigate the current status and influencing factors of medication safety behaviour of operating room nurses. Background Medication safety is an important safety issue reco...
Design, synthesis, and in vitro evaluation of a carbamazepine derivative with antitumor potential in a model of Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is a significant concern in both pediatric and adult demographics. Despite 156 approved cancer therapies based on small molecules, a mere five apply to all types of...
Effects of school menstrual hygiene management, water, sanitation, and hygiene interventions on girls’ empowerment, health, and educational outcomes: Lasta district, Amhara regional state, Ethiopia
This study assessed the effects of school-based menstrual hygiene management (MHM) and water, sanitation, and hygiene (WASH) interventions on the empowerment, health, and educational outcomes of menst...
Needs satisfaction and Online Self-Regulated Learning among chinese undergraduates
The increasing popularity of online courses has highlighted the importance of online self-regulated learning (OSRL). However, its use among undergraduates remains challenging. Based on self-determinat...
Spatiotemporal heterogeneity of bicycle ridership based on GTWR model
As a low-carbon, green and environmentally friendly mode of travel, bicycles possess significant advantages in short-distance trips. In previous studies on the relationship between the built environme...
Outcomes and predictors of in-hospital mortality among patients admitted to the intensive care or step-down unit after a rapid response team activation: A retrospective cohort study
Introduction It has been demonstrated that the implementation of rapid response teams (RRT) may improve clinical outcomes. Nevertheless, predictors of mortality among patients admitted to the intensiv...
The canine vaginal microbiome during heat and fertility in healthy breeding dogs
A healthy and balanced vaginal microbiome is often thought to be an important prerequisite for successful breeding and healthy litters. Previous studies investigating the influence of canine vaginal b...
Environmental persistence of nontyphoidal Salmonella in an urban informal settlement in Nairobi, Kenya
Non-typhoidal Salmonella (NTS) presents a considerable health threat to children in low-resource settings, where clean water, sanitation, and hygiene are often inadequate. However, the environmental f...
Memory Monitoring Recognition Test (MMRT), a new measurement of stimular source monitoring: Software and comprehension
Background Reality monitoring allows the evaluation and monitoring of reality through the assignment of information to internal or external sources, which is crucial to differentiate real events from...
Platelet-rich plasma: A promising therapy for mitigating sperm oxidative stress and mitochondrial dysfunction in subfertile men
Platelet-rich plasma (PRP) is a pioneering therapy widely used in various medical fields, showing promising outcomes. However, its impact on human sperm quality remains poorly explored among emerging...
RWOA: A novel enhanced whale optimization algorithm with multi-strategy for numerical optimization and engineering design problems
Whale Optimization Algorithm (WOA) is a biologically inspired metaheuristic algorithm with a simple structure and ease of implementation. However, WOA suffers from issues such as slow convergence spee...
Daily high doses of atorvastatin alter neuronal morphology in a juvenile songbird model
Statins are highly effective and widely prescribed cholesterol lowering drugs. However, statins cross the blood-brain barrier and decrease neural cholesterol in animal models, raising concern that lon...
Exploring vaccination attitudes in African communities in Canada: A mixed-methods study protocol
Introduction Vaccine hesitancy is a complex issue influenced by many interacting factors. While literature on its contributing causes continues to expand, there is limited research on the contextual a...
Mathematical modelling of reoviruses in cancer cell cultures
Oncolytic virotherapy has emerged as a potential cancer therapy, utilizing viruses to selectively target and replicate within cancer cells while preserving normal cells. In this paper, we investigate...
Research on the balanced, coordinated and sustainable development of China manufacturing industry
China’s manufacturing industry faces the multiple goals of balanced, coordinated and sustainable development. This paper clarifies the connotation of balanced, coordinated and sustainable development...
Expression and immunological role of FUNDC2 in pan-cancer
FUNDC2 is a novel mitochondrial protein and is highly involved in various cancers. However, expression pattern and possible role and mechanism of FUNDC2 in pan-cancer remain to be investigated. TIMER...
Factors affecting online health information-seeking behavior in young and middle-aged patients with stroke
This study aimed to explore the characteristics of online health information-seeking behavior and the influencing factors among young and middle-aged Chinese patients with stroke. The participants of...
Surface Water Microplastics in the St. Lawrence River and Estuary in Canada
Microplastics (MPs) are synthetic or semisynthetic polymers that are widely distributed throughout most ecosystems and have the potential to be harmful to living organisms. In this study, we assessed...
Therapeutic potential of Bacopa monnieri extracts against hepatocellular carcinoma through in-vitro and computational studies
Background Among various cancers, primary liver cancer is the seventh most diagnosed malignancy and is the second most prevalent contributor to cancer-causing deaths. During conventional treatment, th...
SORFPP: Enhancing rich sequence-driven information to identify SEPs based on fused framework on validation datasets
Background Genome sequencing has enabled us to find functional peptides encoded by short open read frames (sORFs) in long non-coding RNAs (lncRNAs). sORFs-encoded peptides (SEPs) regulate gene express...
Transmission matrix parameter estimation of COVID-19 evolution with age compartments using ensemble-based data assimilation
The COVID-19 pandemic, with its multiple outbreaks, has posed significant challenges for governments worldwide. Much of the epidemiological modeling relied on pre-pandemic contact information of the p...
Impact of memory T cells on SARS-CoV-2 vaccine response in hematopoietic stem cell transplant
During the COVID-19 pandemic, hematopoietic stem cell transplant (HSCT) recipients had elevated mortality rates from SARS-CoV-2 infection, ranging between 10–40%. SARS-CoV-2 mRNA vaccines are importan...