PLoS ONE
Articles in this Issue
Changes in the relationship between attachment and emotion recognition from adolescence to adulthood
The present study investigated the relationship between attachment and emotion recognition in adolescents and adults. While previous research has found an association between these constructs in young...
Awareness, knowledge and belief regarding bitter leaf use: A cross-sectional study in Nigeria
Background Vernonia amygdalina, also known as bitter leaf, is a plant that is widespread in Nigeria. Bitter leaf plant has several medicinal properties, and the plant is also widely used due to its va...
Discovery of novel targets for important human and plant fungal pathogens via an automated computational pipeline HitList
Fungi are a major threat to human health and agricultural productivity, causing 1.7 million human deaths and billions of dollars in crop losses and spoilage annually. While various antifungal compound...
Gut microbiota and its influence on the Gut-Brain axis in comparison with chemotherapy patients and cancer-free control data in Breast cancer—A computational perspective
Breast cancer (BC) continues to be a major cause of cancer-related illness and death among women worldwide. Traditional treatments include surgery, radiation, hormone therapy, and chemotherapy, but th...
Influence of near-fault ground motions’ characteristics on the control performance of tuned viscous mass damper systems
Near-fault ground motions, characterized by pronounced pulse and forward-directivity effects, present significant challenges to dampers’ effective performance in controlling seismic activity. This stu...
Evaluating the Safe Steps for De-escalation: A protocol for a mixed concurrent control study in acute mental health units
There is a shared goal of organising reform efforts in mental health services to eliminate restrictive practices and improve therapeutic relationships. However, evidence on high-quality, culturally sa...
Defining and measuring acceptability of surgical interventions: A scoping review
Background Acceptability, in the context of healthcare interventions is a frequently used term, including in evaluations of surgical interventions. This reflects the importance of the concept to all s...
Neuromechanisms and subjective experiences during human-dog interactions: Assessing motivation and mental state in a randomized, controlled trial
Animal Assisted Interventions (AAIs) have been shown to have several effects in humans but the underlying cerebral mechanisms are still widely unknown. This research explored the neurological aspects...
Assessing generalizability of a dengue classifier across multiple datasets
Early diagnosis of dengue fever is important for individual treatment and monitoring disease prevalence in the population. To assist diagnosis, previous studies have proposed classification models to...
Research and analysis of an enhanced genetic algorithm identification method based on the LuGre model
Nonlinear friction in high-precision, ultra-low-speed servo systems severely degrades performance, causing low-speed crawling, static errors, and limit-cycle oscillations. This study introduces the Lu...
Children as controls in research; The voice of the volunteer
Background Modern paediatric healthcare is increasingly dependent on diagnostic methods such as imaging and blood samples. These methods require knowledge of physiology and anatomy to separate signs o...
Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice
Enteropeptidase (EP; enterokinase) is a serine protease that regulates intestinal protein digestion by converting trypsinogen into active trypsin, and thus initiates activation of the pancreatic zymog...
Blockchain enabled privacy provisioning scheme for location based services in VANETs
In recent years, vehicular ad hoc networks (VANETs) have emerged as a crucial component of intelligent traffic systems, offering enhanced road safety through autonomous, distributed, and dynamically s...
Social bonding between humans, animals, and robots: Dogs outperform AIBOs, their robotic replicas, as social companions
In the evolving landscape of technology, robots have emerged as social companions, prompting an investigation into social bonding between humans and robots. While human-animal interactions are well-st...
Evaluation of an evidence-based practice continuing education course for Canadian Naturopathic Doctors
Background Evidence-based practice (EBP) combines the best available evidence with clinician expertise and patient preference to improve patient outcomes. Recent evidence indicates that Canadian Natur...
A dynamic early-warning method for bridge structural safety based on data reconstruction and depth prediction
The structural response of bridges involves a complex interplay of various coupled effects, rendering the identification of long-term variation trends inherently challenging. Consequently, effectively...
Perish the thawed? EDTA reduces DNA degradation during extraction from frozen tissue
Cryopreservation is the gold standard for preserving high molecular weight (HMW) DNA (>10 kb) in tissue samples. However, frozen tissues are typically thawed either before or during DNA extraction,...
A physician-pharmacist partnership intervention for deprescribing (P3iD) among older adults attending a falls and syncope clinic: Protocol for a randomised controlled trial
Background The concept of deprescribing is gaining traction among clinicians as a formalized approach to improving medication safety for older persons. It has been found to be safe and effective in re...
Evaluation of pre-analytical specimen rejection using Six Sigma metrics: A retrospective single-center study
Background Up to 60% of errors occur in the pre-analytical stage of laboratory testing, potentially impairing clinical decision-making. This study aimed to assess pre-analytical errors using Six Sigma...
Effects of nutritional interventions on nutritional and immunological status and adherence to antiretroviral treatment among adults living with HIV in low- and middle-income countries: Systematic review and meta-analysis
Background HIV/AIDS may cause malnutrition, both directly and indirectly, through common infections. This systematic review and meta-analysis aim to evaluate the effects of nutritional interventions o...
Exploring Chinese house prices affordability in the context of confucian culture
Considering the notable influence of traditional Confucian culture on China’s housing market, this study introduces an innovative index to quantify the magnitude of the real estate bubble within China...
Retraction: Knowledge, attitudes, and practices of orthopedic operating room personnel regarding the use of pneumatic tourniquets
Antibacterial, antibiofilm and anti-quorum sensing activities of 1,2,3,5-tetrazine derivatives linked to a benzothiazole moiety
A series of known tetrazine derivatives, containing benzothiazole scaffold, were prepared during the coupling reactions of selected diazotized 2-aminobenzo[d]thiazole derivatives with p-acetaminophen....
Establishment and validation of an interactive web-based calculator for predicting postoperative functional recovery in metatarsal fracture patients: A LASSO regression model approach
Background Metatarsal fractures rank among the ten most common fractures.Comprehensive studies on postoperative functional recovery remain limited. A reliable predictive model for recovery outcomes is...
Short communication: Timber harvesting impacts small mammal foraging behavior and larval tick infestation
Small mammals are important blood-meal hosts for the blacklegged tick, Ixodes scapularis, and reservoirs for the pathogens it transmits. Timber harvesting, a widespread forest management practice with...