PLoS ONE
Articles in this Issue
Enhanced power density in solid oxide fuel cells using nickel-assisted gadolinium-doped ceria anodes
This study demonstrates the use of Gadolinium-doped ceria (GDC) (Ce₀.Gd₀.₂O₂) as the anode, BaNb₄MoO₂₀ (BNMO) as the electrolyte, and Lanthanum strontium cobalt oxide (LSCO) (La₀.Sr₀.₄CoO₃) as the cat...
Development and feasibility of a driving training program for Autistic student drivers
Driving licencing rates remain lower for autistic individuals capable of driving a motor vehicle, which can limit achieving independence in community mobility. However, there is limited autism-specifi...
Heavy metal distribution and ecological risk in surface sediments of the Bohai Sea
Heavy metal contamination in marine sediments poses significant ecological risks, particularly in semi-enclosed seas like the Bohai Sea, where limited water exchange exacerbates pollution retention. H...
Predicting trajectories of the north star ambulatory assessment total score in Duchenne muscular dystrophy
The North Star Ambulatory Assessment (NSAA) is a widely used functional endpoint in drug development for ambulatory patients with Duchenne muscular dystrophy (DMD). Accurately predicting NSAA total sc...
Effects of Conocarpus lancifolius and crocin on superoxide dismutase and protein kinase B genes and protein expressions in diabetic rats
Background Diabetes mellitus, characterized by chronic hyperglycemia, is a global health challenge. Effective management strategies often focus on improving insulin sensitivity and enhancing antioxida...
Mirror, mirror on the coast: Exploring body image perception and its nexus with self-esteem, mental well-being among student population at an education hub in South-India
Introduction Young people’s body image dissatisfaction (BID) is a worrying problem that could impact both their physical and mental health. In addition to determining the prevalence and severity of BI...
Increased sensitivity of primary aniridia limbal stromal cells to travoprost, leading to elevated migration and MMP-9 protein levels, in vitro
Purpose In congenital aniridia, not only limbal epithelial cells but also limbal stromal cells may contribute to the development of aniridia associated keratopathy (AAK). Secondary glaucoma affects 50...
Neural mechanisms of emotion during shifting perspectives and recognizing new information: An fMRI study
In generating novel ideas during the creative process, what ignites positive emotions like “Aha” experiences of insight? This study explored this by validating the biological plausibility of a mathema...
Study on the influence of customers’ consumption intention in online food delivery service: Calorie label as the moderator variable
Online food delivery (OFD) service, is a catering service model taking the Internet as the platform, where customers place orders online and enjoy offline delivery services. Customers’ attention on ca...
Association between functional dentition and ultra-processed food consumption in Brazilian adults: A cross-sectional study
Objective This study aimed to verify if there is an association between functional dentition and ultra-processed diet in Brazilian adults. Methods This cross-sectional study used data from the Natio...
Heavy metals in essential oils proposed for the modification of footwear lining leather—Quality management and product safety
Due to their antiseptic action, essential oils can be incorporated into leather in order to improve the hygienic properties of footwear by reducing microbial growth and multiplication in the interior....
Progression and natural history of Atypical Parkinsonism (ATPARK): Protocol for a longitudinal follow-up study from an underrepresented population
Background Atypical Parkinsonian Syndromes (APS) form the third largest group of neurodegenerative disorders including Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA), and Corticob...
Groupwise registration of infant brain diffusion tensor images using intermediate subgroup templates
Registering infant brain images is challenging, as the infant brain undergoes rapid changes in size, shape and tissue contrast in the first months of life. Diffusion tensor images (DTI) have relativel...
Protocol for a Hybrid-type 1 pilot study of a randomized control trial of a brief, peer-delivered treatment to improve father depression and child mental health in Kenya
Background Few treatments specifically target father depression and alcohol use, despite their high prevalence worldwide and adverse impacts on families and youth. Fathers are also less likely to enga...
Research on mechanical characteristics and key technology of integral intelligent lifting construction of large-span heavy steel box girder
This paper aims to address the problems of aerial orientation control and safety in sudden extreme working conditions during the integral intelligent lifting of large-span heavy steel box girder. Base...
Gait kinetics before and after total hip arthroplasty in people with unilateral hip osteoarthritis
Background Total hip arthroplasty (THA) is a common intervention for end-stage osteoarthritis (OA) that improves gait kinetics. However, full restoration of mobility through THA remains elusive. Limit...
Hepatoprotective action of Sonchus oleraceus against paracetamol-induced toxicity via Nrf2/KEAP-1/HO-1 pathway in relation to its metabolite fingerprint and in silico studies
Background Paracetamol overdose causes severe hepatotoxicity. Sonchus oleraceus is traditionally used to treat liver disorders, but its potential against paracetamol-induced liver injury is unexplored...
Ivermectin inhibits epithelial-to-mesenchymal transition via Wnt signaling in endocrine-resistant breast cancer cells
Ivermectin (IVM), an antiparasitic drug, has been explored for its anticancer properties in various cancer types, including breast cancer. Endocrine therapy resistance poses a significant challenge in...
From fat to facts: Anthropometric references and centile curves for sum of skinfolds and waist-to-hip ratio in 2,507 adults
Background and aims Direct assessment of skinfold thickness and waist and hip girths provides information about body fat and its distribution, avoiding estimation errors due to predictive equations. T...
SHR-A1811, a novel anti-HER2 antibody–drug conjugate with optimal drug-to-antibody ratio, efficient tumor killing potency, and favorable safety profiles
HER2-targeting antibody–drug conjugates (ADCs), especially trastuzumab deruxtecan (T-DXd), have revolutionized the treatment landscape of HER2-expressing or mutant cancers. However, undesired adverse...
The complex interplay of personal and external factors in medical students’ specialty decision-making: A qualitative study
Background Medical students’ specialty decisions are shaped by a complex interaction of personal characteristics, academic experiences, social influences, and broader contextual factors. In lower-midd...
Diversity in knowledge search paths and breakthrough technological innovation: Evidence from new energy vehicle firms
Breakthrough technological innovations have heralded a transformative era within the automotive industry. Knowledge search diversity, as the key to acquiring the raw materials for knowledge recombinat...
Iron uptake by Escherichia coli in urinary tract infections and urosepsis
The pathogenesis of urosepsis in uncomplicated and community-acquired urinary tract infections (UTIs) caused by Escherichia coli was studied. We hypothesized that siderophores involved in iron uptake...
How to nudge students toward healthier snacks? Consumer neuroscience insights on multisensory nudge interventions in university vending machines
Nudge has proven effective in promoting healthier eating, especially in academic environments. However, its application in vending machines has not been extensively studied yet, with existing studies...
Tooth discoloration caused by nanographene oxide as an irrigant and intracanal medicament in the endodontic treatment of extracted single-rooted teeth: An ex-vivo study
Tooth discoloration caused by intracanal medicaments and irrigants presents a significant aesthetic challenge in dentistry. This study aimed to investigate the discoloration effects on tooth of nanogr...