PLoS ONE
Articles in this Issue
CCR2 overexpressing gingiva mesenchymal stem cells provide high intestinal regeneration in a rat model of ulcerative colitis
Background/aims Ulcerative colitis (UC) is a chronic inflammatory disease affecting the colon. Mesenchymal stem cells (MSCs) are candidates for use in inflammatory diseases with their tissue regenerat...
Asking for help: An empirical exploration into social grammar
This paper explores the interface between linguistic form and social meaning by focusing on correlations between sentence type and the social distance between interlocutors—a central aspect of the soc...
Development and validation of a measurement instrument for student assessment of quality physical education in Chinese secondary schools
There is a growing emphasis on developing Quality Physical Education (QPE) programs. However, a research gap exists due to the lack of measurement instruments to assess QPE for students. This study ai...
Phagocytic activity of blood monocytes and neutrophils in moderate COVID-19 patients and impact of immune therapy with bacterial lysates
Background Monocytes, macrophages and dendritic cells are involved in phagocytic reactions, which potentially play an important role in the pathogenesis of COVID-19. Imbalance of these cells in periph...
Impact of physical activity and psychological skills training with parental participation on cognitive, emotional, and behavioral outcomes in children with ADHD and their parents: A study protocol
Background Attention Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by difficulties in attention, hyperactivity, and impulse control. Previous studies have sugges...
Variants in Lrrk2 and Snca deficiency do not alter the course of primary encephalitis due to neurotropic reovirus T3D in newborn mice
Variants at the leucine-rich repeat kinase-2 (LRRK2) and α-synuclein (SNCA) loci are associated with Parkinson’s disease (PD) risk. Viral infections have also been linked to increased risk of developi...
Geospatial analysis of toponyms in geotagged social media posts
Place names, or toponyms, play an integral role in human representation and communication of geographic space. In particular, how people relate each toponym with particular locations in geographic spa...
Comparing the hamstring muscle activity between injured and non-injured sides during a variety of Nordic hamstring exercises
Objectives To compare the electromyographic activity of the Biceps femoris long head and Semitendinosus muscles during bilateral and unilateral isometric Nordic hamstring exercise performed on an incl...
Quantification of serum elastase inhibitory activity in patients with pulmonary emphysema with and without alpha-1 antitrypsin deficiency
Pulmonary emphysema, a component of chronic obstructive pulmonary disease (COPD) is characterised by irreversible alveolar tissue destruction and is produced by an imbalance between proteolytic enzyme...
Forest structure, timber species regeneration, and timber volume dynamics along a logging gradient in a lowland tropical rainforest in Africa: Implications for biodiversity conservation and sustainable timber management
Timber production, cutting and extraction is impacting vast areas of tropical forests, highlighting the need for management strategies to promote sustainable recovery of logged forests. However, limit...
Qualitative analysis of elite football players’ causal attribution to not playing: A perspective of attribution theory
This study explores the causal attributions of professional football players who experience reduced playing time or exclusion from the squad, focusing on the psychological and relational consequences...
Association between serum uric acid to high-density lipoprotein ratio and all-cause in hypertensive patients: Mediating role of neutrophils
Background The aim of this study was mainly to investigate the association between Serum uric acid (SUA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) and all-cause mortality in hyperten...
Research on forward multi-step prediction of EU carbon prices considering multiple factors new evidence from a hybrid model combining secondary decomposition technique and transformer
An accurate prediction of carbon pricing is essential in carbon emission management, and also provides an important role for governments to formulate corresponding policies. However, due to the inhere...
Analyzing the evolutionary trajectory of technological themes based on the BERTopic model: A case study in the field of artificial intelligence
As the wave of technological innovation propels national development into the future, technological advancement has emerged as a crucial pillar for enhancing international competitiveness. Unraveling...
Factors associated with breast lesions among women attending select teaching and referral health facilities in Kenya: A cross-sectional study
Despite extensive research on the risk factors for breast cancer, little is known about the factors contributing to other breast lesions, of which some pose an increased risk for this disease. The obj...
Long-term pulmonary sequelae and convalescent immune reactions in mild to moderate COVID-19 patients during the active treatment era
Background During the COVID-19 endemic phase, pulmonary sequelae substantially contributed to disease burden. Immunologic responses may be critical in both acute COVID-19 and in long-term sequelae. We...
An effective approach for fault diagnosis: Conflict management and BBA generation
Evidence Theory (ET) is widely applied to handle uncertainty issues in fault diagnosis. However, when dealing with highly conflicting evidence, the use of Dempster’s rule may result in outcomes that c...
Influence of enclosure design on the behaviour and welfare of Pogona vitticeps
Complex or naturalistic enclosures have become increasingly accepted as those best-suited to improve an animal’s welfare. However, designing such enclosures can be difficult if little is known about t...
Vascular dysfunction is associated with major adverse cardiovascular events in prediabetes: A cohort study
Background Prediabetes is a growing public health concern that increases the risk of major adverse cardiovascular events (MACE). Vascular dysfunction worsens with hyperglycemia and is associated with...
Modeling of wheelchair movement trajectory error and analysis of self-correcting control mechanism in disabled table tennis
A wheelchair kinematic model was constructed to address the wheelchair control problem in table tennis for disabled individuals. The influence of slipping factors was considered, and a differential mo...
A real-world disproportionality analysis of Tenofovir Alafenamide (TAF): Data mining of the FDA adverse event reporting system (FAERS)
Objects Tenofovir Alafenamide (TAF) is a novel antiviral drug approved for the treatment of hepatitis B virus (HBV) infection. Our research objective was to evaluate the safety characteristics of TAF...
Retraction: Receptor-Recognized α2-Macroglobulin Binds to Cell Surface-Associated GRP78 and Activates mTORC1 and mTORC2 Signaling in Prostate Cancer Cells
Clinical and economic burden of surgical site infections following selected surgeries in France
In France, surgical site infections (SSIs) are the second most frequent hospital-acquired infection. The study aimed to estimate the in-hospital clinical and economic burden of SSIs following 4 groups...
Examining the inaccurate reproductive health messaging of crisis pregnancy centers: A comparative qualitative study
Objectives Given the prevalence of inaccurate or misleading health messaging linked to crisis pregnancy centers (CPCs) in the literature, we sought to understand what role, if any, standardized traini...
The balance stabilising benefit of social touch: Influence of an individual’s age and the partner’s relative body characteristics
Interpersonal touch (IPT) is a successful strategy to support balance during a wide range of activities in daily life, including physical education and therapy. Despite common practice, however, the i...