PLoS ONE
Articles in this Issue
Mental health literacy in nursing students: Insights from a cross-sectional analysis
Mental health literacy is crucial for nursing students to deliver effective patient care; however, its development throughout their academic journey remains underexplored. This study aimed to assess m...
RNA-mediated gene silencing can reduce azole resistance, growth and pathogenicity in Pseudocercospora fijiensis
The use of double-stranded RNA (dsRNA) gene silencing has allowed significant advances in the understanding of gene function in many organisms and has the potential for use in disease control. At pres...
Innovating under different competitive strategies: The impact of R&D on risk and return in dynamic environments
The prevailing narrative in the management literature views R&D as a high-risk, high-return activity. Although firms with varying risk-return preferences pursue R&D, this conventional perspect...
Fixation drift increases as a function of time-on-task in a brief saccade tracking study
Ocular fixations contain microsaccades, drift and tremor. We report an increase in the slope of linear fixation drift as a function of time-on-task (TOT). We employed a large dataset (322 subjects, mu...
Association between Platelet Count and In-Hospital Mortality in Critical Patients with Multiple Myeloma: A Cohort Study
Background Multiple myeloma (MM) is a malignant blood disease characterized by the abnormal proliferation of immature plasma cells in the bone marrow. Changes in platelet counts (PLT) may significantl...
KIFC1 inhibition: Exploring the potential of propolis-derived small molecules for targeting cancer progression through in silico analysis
Propolis, a resinous compound produced by bees, possesses diverse medicinal properties and has gained significant attention for its potential in cancer therapy. This study investigated the therapeutic...
Predictors of institutional delivery service utilization among women in Northern region of Ghana
Introduction An increase in home delivery among expectant mothers may likely lead to high maternal and newborn morbidities and mortalities. Despite the policy on free maternal healthcare in Ghana unde...
Beyond the medical file: A scoping review on patients’ perspectives on depression treatment in primary care
Objectives Depressive disorders are common in the primary care setting. Despite its high prevalence, depression treatment in primary care is less guideline-oriented compared to specialized settings, w...
Developmental transcriptomics of the Firebrat: Exploring developmental expression patterns and morphology during the embryogenesis of Thermobia domestica
Understanding the development of early-diverging lineages is crucial for inferring evolutionary context in evolutionary developmental biology. Thermobia domestica (the firebrat), a member of Zygentoma...
Assessing the impact of internet-based cognitive behavioral therapy on sexual dysfunction: A systematic review protocol
Introduction Sexual dysfunction (SD), a prevalent health concern, can significantly impact an individual’s overall well-being and intimate relationships. Internet-based cognitive behavioral therapy (I...
Shifts in phytoplankton community structure across oceanic boundaries
Phytoplankton communities play an important role in marine food webs and biogeochemical cycles. The transition zones between ocean gyres and surrounding waters represent critical ecological boundaries...
Determinants of jaundice severity in neonates admitted at a Teaching Hospital in Ghana
Background Severe neonatal jaundice (NJ) is associated with significant morbidity and mortality globally with low and, middle income countries having a greater burden. Increased red blood cell destruc...
Progress in developing a bark beetle identification tool
This study presents an initial model for bark beetle identification, serving as a foundational step toward developing a fully functional and practical identification tool. Bark beetles are known for e...
Body mass index mediates the association between sleep duration and academic performance: An evidence in Chinese adolescent students
Background Academic performance serves as a crucial indicator for evaluating adolescents’ educational outcomes in China, which prompting parents and schools to place significant emphasis on students’...
Resistance trend in bacteria isolated from corneal ulcers: A retrospective analysis from Pakistan
Objective The purpose of this study is to isolate and characterize bacteria from corneal ulcers and screen them for multiple antibiotic resistance, contributing to understanding patterns of resistance...
Multidimensional performance enablers of Ethiopian community-based health extension program: A scoping review
Introduction Ethiopian Health Extension Program (HEP) aims to improve access to primary care, yet suboptimal health outcomes persist, indicating the need to optimize HEP implementation. This scoping r...
IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice
Neurotropic viruses are a major public health concern as they can cause encephalitis and other severe brain diseases. Many of these viruses, including flaviviruses, herpesviruses, rhabdoviruses and al...
Correction: DNA Barcode, chemical analysis, and antioxidant activity of Psidium guineense from Ecuador
Clinical profile and treatment outcomes of acute lymphoblastic leukemia among children attending at the University of Gondar comprehensive specialized hospital and Tikur Anbessa Specialized Hospital in Ethiopia
Background Acute lymphoblastic leukemia (ALL) is a common childhood cancer characterized by the uncontrolled proliferation of immature white blood cells. While advancements in treatment have significa...
Rivalry between pitch and timbre in auditory stream segregation
Two rapidly alternating tones with different pitches may be perceived as one integrated stream when the pitch differences are small or two separated streams when the pitch differences are large. Likew...
Optimization of Z-shaped assembled mortise and tenon joint box culvert connection and structural characteristics
This paper proposes a new type of Z-shaped prefabricated mortise and tenon joint box culvert designed to enhance the longitudinal connection stability of highway prefabricated box culverts. Using actu...
Misophonia impact questionnaire (MIQ), tinnitus impact questionnaire (TIQ), and hyperacusis impact questionnaire (HIQ): Factor analysis, test-retest reliability, and minimum detectable change using a non-clinical population
The objectives of this study were to (1) assess if previously reported unidimensional factor structure of the Misophonia Impact Questionnaire (MIQ), Tinnitus Impact Questionnaire (TIQ), and Hyperacusi...
Axisymmetric adaptive upper-bound finite element limit analysis formulation based on second-order cone programming for bearing capacity of circular footing
An adaptive axisymmetric upper bound finite element limit analysis (UB-FELA) formulation has been presented for Mohr-Coulomb (M-C) materials in this paper. The computational domain is discretized usin...
The effect of foliar spraying of silver and iron nanoparticles as fertilizers on the quantity, quality, and antimicrobial properties of Melissa officinalis L. essential oil
Melissa officinalis L. as a medicinal plant used in traditional medicine to treat headaches caused by stress, anemia, nausea, dizziness, indigestion, colic, epilepsy, hysteria, cancer, and heart failu...
Exploring new lengths for q-ary quantum MDS codes with larger distance
In the past decade, the construction of quantum maximum distance separable codes (MDS for short) has been extensively studied. For the length n=q2−1m, where m is an integer that divides either q + 1...