PLoS ONE
Articles in this Issue
The effect of follicular and ampullary fluid extracellular vesicles on bovine oocyte competence and in vitro fertilization rates
Follicular fluid from preovulatory follicles as well as ampullary fluid from slaughtered cows at the early metestrus were collected for isolation of EVs. Excellent and good quality bovine oocytes were...
Expressing intrinsically-disordered tardigrade proteins has positive effects on acute but not chronic stress tolerance in Saccharomyces cerevisiae
The production of high value and commodity chemicals, biopharmaceuticals and biofuels using Saccharomyces cerevisiae is hindered by various stress factors that affect yield and efficiency. Tardigrades...
Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice
Visceral haemangiosarcoma is considered clinically aggressive in dogs, with perceived poor prognosis often leading to euthanasia at presentation. This study aimed to determine survival times and progn...
Physiological and psychological responses to five-day fasting
The objective of this study was to examine the variations in adipokines, myokines, inflammation indicators, glucose, insulin, and ketones in the body over a 5-day fasting period. Additionally, the stu...
A Mallows-like criterion for anomaly detection with random forest implementation
Anomaly detection plays a crucial role in fields such as information security and industrial production. It relies on the identification of rare instances that deviate significantly from expected patt...
Blockchain-based zero trust networks with federated transfer learning for IoT security in industry 5.0
The rise of Industry 5.0 focuses on merging advanced intelligence, automation, and human-centered teamwork in industrial settings. However, keeping interconnected IoT networks secure is still a challe...
Toward resilient cities: Mapping the interconnected factors shaping urbanization in a dual analysis framework
Utilizing the Push and Pull theory, this study examines the impact of socio-economic disparities and natural disasters on migration and urbanization. With a global significance, the shift of populatio...
Global burden and future trends of inguinal, femoral, and abdominal hernia in older adults: A systematic analysis from the Global Burden of Disease Study 2021
Objective This study aims to comprehensively evaluate the global, regional, and national burden, trends, and health inequalities of inguinal, femoral, and abdominal hernias among older adults from 199...
Instability of estimation results based on caliper matching with propensity scores
Caliper matching is often used to adjust for confounding biases in observational studies. This method with random order matching allows for the cherry-picking of the analysis results to suit the analy...
The “Dogs’ Catching Mice” conjecture in Chinese phonogram processing
In Chinese phonogram processing studies, it is not strange that phonetic radicals contribute phonologically to phonograms’ phonological recognition. The present study, however, based on previous findi...
Prevalence of influenza A and B and respiratory syncytial virus infections before and during COVID-19 pandemic in the pediatric population in Lebanon: A retrospective study
Seasonal influenza and RSV outbreaks cause considerable morbidity and mortality in the pediatric population worldwide. The COVID-19 pandemic has changed virus epidemiology. Until today, it is still un...
How trustworthy and applicable is the evidence from systematic reviews of depression treatments: Protocol for systematic examination
Background Depression is a common mental disorder significantly impacting daily functioning. Standard treatments include drugs, psychotherapies, or a combination of both. Treatment selection relies on...
Efficacy and safety of Tuina (Chinese Therapeutic Massage) for chronic ankle instability: A systematic review and meta-analysis of randomized controlled trials
Objective The efficacy of tuina in treating chronic ankle instability (CAI) arouses controversy. Therefore, the present study adopted the meta-analysis to evaluate the effectiveness and safety of tuin...
Identification and characterization of eccDNA-driven genes in humans
Extrachromosomal circular DNA (eccDNA) amplification promotes oncogene expression and cancer development. However, the global transcriptional landscape mediated by eccDNA has not yet been extensively...
Editorial Note: Machine learning model for predicting the optimal depth of tracheal tube insertion in pediatric patients: A retrospective cohort study
Visual feature analysis on selective appetite in individuals with autism spectrum disorders
Background Individuals with autism spectrum disorders (ASD) experience more severe selective eating problems than their neurotypical peers. Identifying the causes of selective eating behavior poses a...
A deep dive into the coelacanth phylogeny
The discovery in 1938 of a living coelacanth, Latimeria chalumnae, triggered much research and discussion on the evolutionary history and phylogeny of these peculiar sarcopterygian fishes. Indeed, coe...
The various effect of social isolation on depression risk among old population in China during covid-19 pandemic: A population based survey
Background The aim of the current study is to assess various effect of social isolation on depression risk among older adults during COVID-19 in China. Methods Data was obtained from the China Longi...
Leveraging technology to probe mechanisms of psychopathology: A proof of concept study of inhibitory control
Objective Quantifying relevant behavioral mechanisms has relied on rigorous, time-consuming tools restricted to laboratory settings and inaccessible to the clinical community. Advances in technology p...
Exploring factors impacting Hispanic/Latinx individuals’ response to a type 2 diabetes digital storytelling intervention
Background Hispanic/Latinx individuals have high prevalence of type 2 diabetes and its complications yet often face barriers in accessing diabetes prevention and self-management interventions. One pos...
Estimating sales transitions between competing products via optimal transport
In mature markets, where products are widely adopted, understanding how customers switch between competing products is crucial for companies to conduct effective marketing actions. However, due to pri...
The TMA team and TTP pathway improved outcomes in a cohort with Thrombotic thrombocytopenic purpura
Background Providing optimal care for patients with thrombotic thrombocytopenic purpura (TTP) is challenging because of multiple involved specialties, knowledge gaps, and a high rate of disease relaps...
The application of deep learning in economic analysis and marketing strategy formulation in the tourism industry
The tourism industry is ever-evolving in nature, as it operates in a global marketplace that has become progressively global and offers great potential due to technological advances. The tourism indus...
Human umbilical cord mesenchymal stem cell-derived exosomes mitigate acute radiation-induced intestinal oxidative damage via the Nrf2/HO-1/NQO1 signaling pathway
Acute radiation-induced intestinal injury (ARII), a prevalent complication of abdominal radiotherapy, remains clinically challenging due to limited therapeutic options. This study demonstrates the the...
Parental experience of the diagnostic process and its role in the decision to terminate pregnancy due to fetal abnormality; A qualitative interview study
Introduction The detection of fetal malformation is a shock to expectant parents and often initiates a diagnostic process of additional tests and ultrasound scans, that may be uncertain and stressful...