PLoS ONE
Articles in this Issue
Evaluating the effectiveness of integrating biofeedback in the treatment of aggressive outbursts (BRET-IA2): A study protocol
Introduction: This study provides a comprehensive overview of the materials and methods used to evaluate the effectiveness of the use of biofeedback in the treatment of aggressive episodes in children...
The role of individual recognition in shaping empathy and trust toward an agent
When individuals receive assistance, the principle of reciprocity is often triggered. In social contexts, whether the actors are humans or AI/robots (hereafter referred to as agents), multiple individ...
Circadian rhythm genes and immune cell infiltration in myasthenia gravis: A comprehensive analysis
The fluctuating weakness in myasthenia gravis (MG) is clinically described as the “morning improvement and evening worsening” pattern; MG is commonly associated with sleep disorders. However, there re...
pET28g: A Golden Gate-compatible pET vector for protein expression in Escherichia coli, validated by production of functional human ACE2
The pET28g plasmid is a new tool for protein expression in Escherichia coli. It was derived from pET28a by replacing the traditional multiple cloning site with a Golden Gate cassette containing the la...
The relationship between confidence and gaze-at-nothing oculomotor dynamics during decision-making
How does confidence relate to oculomotor dynamics during decision-making? Do oculomotor dynamics reflect deliberation and the buildup of confidence in the absence of visual stimuli? Here we examine th...
The impact of maternal gum disease on pregnancy outcomes using PRAMS data
Background Gum disease during pregnancy is not just a dental issue but a significant public health concern with potential implications for maternal and child health. This study aims to estimate the na...
Use of female-controlled dual protection methods among adolescent girls and young women living with HIV in Northern Uganda: A convergent mixed-methods study
Background Adolescent girls and young women living with HIV (AGYWLHIV) in Uganda face dual risks of HIV transmission to male partners and unintended pregnancies. Male condoms require male partner coop...
A syllable-character collaborative model for enhanced Pinyin and Chinese recognition
In Chinese speech recognition, end-to-end speech recognition models usually use Chinese characters as direct output and perform poorly compared with other language models. The main reason for this phe...
Epidemiological characteristics and management of Gram-negative bacteraemia in different immunocompromised hosts: Observational single-center study
Importance Patients with Gram-negative bloodstream infections (GN-BSI) are classified as non-immunocompromised (n-IC) or immunocompromised (IC). However, immunosuppressive condition should not be cons...
The application of CBL and mind mapping combined with Mini-CEX teaching mode in the cultivation of clinical competence of ultrasound residents
Objective This study aims to evaluate the efficacy of the Mini Clinical Evaluation Exercise (Mini-CEX) in conjunction with Case-Based Learning (CBL) and mind mapping methodologies in fostering the cli...
Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches
Background Peritonsillar abscess (PTA) is a prevalent infection for specialists in otorhinolaryngology and pediatric primary care providers, that has the potential to cause severe complications. The a...
Correction: Research on simulation of permanent magnet synchronous motor in full speed range
Mapping the effective coverage of modern contraceptive services in Ethiopia
Introduction Modern contraceptive services are vital for reducing maternal and infant morbidity and mortality. However, in Ethiopia, the effective coverage (quality-adjusted coverage) of these service...
Employee engagement mediates person-environment fit and new employees’ innovative behavior: A multidimensional perspective
New employees can bring new perspectives and vitality to the organization. Creating a suitable environment for new employees to innovate, maintain their work enthusiasm, and stimulate their innovative...
An in vitro model to study molecular pathogenesis of sarcopenia established by a SASP-dependent human myotube culture
Sarcopenia is a condition that affects one’s activities of daily livingand is rapidly increasing with the ages of the global population. However, the basic molecular mechanisms for prevention and trea...
Calibration of parameters in microscopic traffic flow simulation models considering micro-meteorological information
Different micro-meteorological conditions can affect a driver’s judgment of road conditions, leading to changes in following behavior. On rainy days, water films on the road reduce traction, increasin...
Quantitative attribution of spatio-temporal pattern of pm2.5 concentration based on geodetector and GWR model: Evidence from China’s three major urban agglomerations
Clarifying the spatio-temporal evolution of PM2.5 concentration law and its driving mechanism is crucial for the prevention and control of air pollution in urban agglomerations, also helping promote t...
Changes in heart rate variability and hemodynamics of adolescents within the frontal cortex in response to face emotional stimulation
Background Functional near-infrared spectroscopy (fNIRS) and heart rate variability (HRV) are commonly utilized biomarkers for assessing emotional states. This study hypothesizes that emotional percep...
Fixed point-based stability analysis of climate and Langevin models
In this manuscript, the existence and uniqueness of solutions to equations associated with climate change are discussed. For this purpose, we utilize some results from the existing literature to inves...
Exploring the challenges and opportunities of multisectoral nutrition programme in Ethiopia: A qualitative study on combating undernutrition during pregnancy
Background Despite evidence of the benefits of multisectoral nutrition programmes in reducing undernutrition among vulnerable groups such as pregnant women, implementation is not as expected for reaso...
Investigating SnOx/Graphene Oxide heterostructure for methane sensing and its application as a tunable light absorber for optoelectronic devices
This study investigates the optical and electronic properties of SnOx/Graphene Oxide (SnOx/GO) heterostructures, focusing on their sensitivity and selectivity to methane adsorption and its tunable lig...
Association of monocyte and lymphocyte ratio with risk of abdominal aortic calcification
Objectives The aim of the study was to evaluate the relationship between monocyte and lymphocyte ratio (MLR) with severe AAC. Methods This cross-sectional study enrolled 3041 patients with AAC from...
Impact of the dimple indentation depth and location for passive flow control in Blended Wing Body airframe at low and high subsonic speeds
This research investigates the role of dimples in enhancing the aerodynamic characteristics of a Blended-Wing-Body (BWB) airframe. Numerical simulations, grounded in Computational Fluid Dynamics (CFD)...
Tracing the function expansion for a primordial protein fold in the era of fold-based function prediction: β-trefoil
The incredibly narrow protein fold bottleneck, which separates the billions of unique proteins on one side to deliver diverse biological functions on the other, arises from folds that tolerate mutatio...
Breaking barriers for TB elimination: A novel community-led strategy revolutionizing tuberculosis case finding and treatment support in Senapati District Manipur-A quasi-experimental pre-post study protocol
Introduction Despite being the world’s highest tuberculosis (TB) burden country, India still misses millions of TB cases annually. To address this issue, the India National Strategic Plan, following W...