An intelligent diagnosis method for cardiovascular diseases based on the CNN-CBAM-GRU model

Z Zheng Gong (Interdisciplinary Center for Quantum Information, State Key Laboratory of Extreme Photonics and Instrumentation, College of Information Science and Electronic Engineering, Zhejiang University) Y Yufeng Chen (Power Battery & Systems Research Center, State Key Laboratory of Catalysis) S Shirong Lin J Jun Ke J Juying Huang H Hongyi Chen (College of Chemistry and Chemical Engineering) H Hongyu Huang Y Yue Shen Y Yi Gu L Lixun Chen (Innovative Centre for Flexible Devices (iFLEX), Max Planck-NTU Joint Lab for Artificial Senses, School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Republic of Singapore) F Feng Chen

Abstract

Early diagnosis of cardiovascular diseases (CVDs) is essential for improving patient outcomes. As a primary diagnostic modality, electrocardiogram (ECG) signals pose challenges for automatic classification due to their complex temporal and morphological characteristics. This study proposes a CNN-CBAM-GRU model that integrates Convolutional Neural Networks (CNN), the Convolutional Block Attention Module (CBAM), and Gated Recurrent Units (GRU) to enhance both spatial feature representation and temporal sequence modeling. The model is evaluated on two public ECG datasets—MIT-BIH and PTB-XL—under five-class classification settings. Unlike many existing approaches that report only a limited set of metrics, this study conducts a comprehensive evaluation across multiple performance indicators, including accuracy, precision, recall, sensitivity, and F1-score, providing a more complete view of classification effectiveness. Experimental results demonstrate that the proposed model achieves a strong balance between predictive performance and computational efficiency. Specifically, it achieves 98.17% accuracy and 98.91% F1-score on MIT-BIH, and 99.21% accuracy and 99.47% F1-score on PTB-XL, with a compact parameter size of 2.45 million. These findings validate the proposed model as a practical and robust solution for intelligent ECG classification and automated cardiovascular disease diagnosis.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 9
Published September 02, 2025
Pages e0330279
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (11)

Z

Zheng Gong

Interdisciplinary Center for Quantum Information, State Key Laboratory of Extreme Photonics and Instrumentation, College of Information Science and Electronic Engineering, Zhejiang University

Y

Yufeng Chen

Power Battery & Systems Research Center, State Key Laboratory of Catalysis

S

Shirong Lin

J

Jun Ke

J

Juying Huang

H

Hongyi Chen

College of Chemistry and Chemical Engineering

H

Hongyu Huang

Y

Yue Shen

Y

Yi Gu

L

Lixun Chen

Innovative Centre for Flexible Devices (iFLEX), Max Planck-NTU Joint Lab for Artificial Senses, School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Republic of Singapore

F

Feng Chen