PLoS ONE
Articles in this Issue
An in vitro study on dentin abrasion comparing two sonic toothbrushes with and without a coating versus an ADA reference manual toothbrush
This in vitro study evaluated dentin abrasion and surface roughness caused by two sonic toothbrushes with different filament coatings compared with those caused by a standard ADA reference manual toot...
Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma
FZD7 is one of the key players in the subset of WNT-TGFβ-activated hepatocellular carcinomas (HCC), but the consequences of its abnormal expression on hepatocarcinogenesis remain to be better understo...
Rethinking tube feeding in palliative care: Impact on pneumonia, depression, and mortality in patients with dysphagia and life-limiting illness
Introduction Tube feeding continues to be recommended for nutrition when a patient has dysphagia amid life-limiting illness. Tube feeding is frequently claimed to be a safer alternative to oral feedin...
A study on factors influencing the national carbon emission trading price in China
On 16 July 2021, China officially launched its national carbon emissions trading market, which has since become the largest market in the world in terms of coverage of greenhouse gas emissions and pla...
Stochastic evolution model for international migration
We present a new international migration model that combines stochastic sampling techniques with dynamic accounting of flows by means of evolution equations. Migration flows are sampled from paramater...
Does China’s corporate two-way foreign direct investment mitigate environmental pollution?
The global push for low-carbon growth highlights the urgent need to examine how corporate internationalization shapes environmental performance. However, the environmental implications of corporate tw...
Mitochondrial genomics and phylogeny of noctuoid moths: Implications for Macroheterocera
The majority of the Lepidoptera species belongs to the Macroheterocera clade. The macroheteroceran superfamilies’ phylogenetic relationships are still unstable. The construction of a robust phylogenet...
Estimated glucose disposal rate predicts frailty through diabetes: Evidence from machine learning and mediation models in NHANES
Objective As an emerging insulin resistance marker, the relationship between estimated glucose disposal rate (eGDR) and frailty needs further exploration. This study examines the eGDR-frailty link, de...
Risk factors influencing Coxiella burnetii seropositivity in water Buffalo (Bubalus bubalis) populations of Egypt’s Nile Delta
This study investigated the seroprevalence of Coxiella burnetii in buffaloes across several governorates in Egypt’s Nile Delta. No significant variation was observed between regions (P > 0.05), alt...
Histopathological change of age-related hearing loss in female advance-aged CBA/CaJ mice
With the increase in the older population, the number of individuals with age-related hearing loss is also growing explosively. Therefore, there is an urgent need to identify the detailed pathology of...
Effects of virtual reality-based disaster simulation education on nursing students
Background This study aimed to confirm the effectiveness of disaster simulation education that uses virtual reality (VR). Method This quasi-experimental study was conducted using a non-equivalent co...
Optimal bus bridging service for urban rail transit disruptions with stochastic passenger demand
Disruptions in urban rail transit (URT) systems can significantly impact operational efficiency, while well-designed bus bridging service (BBS) can effectively mitigate such effects. To address the su...
Study protocol for measuring energy needs and nutritional status of adolescent girls in Abia state, Nigeria: The nutrition and adolescence in rural Nigeria (NARN’ia) Study
Background Adolescents in low- and middle-income countries face significant nutritional challenges, including undernutrition, micronutrient deficiencies, poor dietary habits, and food insecurity. Thes...
Exploring health literacy pertaining to general wellbeing and chronic disease management among population registered within Primary Healthcare System: A Study protocol
Background Evidence suggests that high level of health literacy among patients is associated with high levels of accessibility to healthcare, better understanding consent-to-treat forms, increased com...
Home range and activity budget in the Falkland Steamer Duck (Tachyeres brachypterus)
The Falkland Islands support globally important populations of seabirds and coastal birds, underscoring their value for international conservation efforts. However, substantial knowledge gaps impede t...
Global burden of polycystic ovary syndrome in women of reproductive age, 1990–2021: Analysis of the global burden of disease study 2021 with projections to 2050
Objective To evaluate the global burden of polycystic ovary syndrome (PCOS) among women of reproductive age from 1990 to 2021. Methods This study analyzed population-based data from the Global Burde...
Can lipid indices aid in predicting diabetic kidney disease? Findings from a cross-sectional, matched case-control study
Background This study explored the association between lipid indices, including AC, TG/HDL-C ratio, AIP, and LCI, and diabetic kidney disease (DKD). Methods A cross-sectional, matched case-control s...
Exploring regional air pollution transition dynamics: A multi-state markov model approach
Background Air pollution, commonly measured by the Air Quality Index (AQI), is a significant global health risk, yet its transition dynamics remain poorly understood. This study aims to investigate th...
Sleep apnea is associated with reduced in-hospital mortality in patients admitted for acute heart disease
Background: Sleep apnea (SA) is an independent risk factor for many cardiovascular diseases. The impact of SA on the outcome of patients hospitalized due to cardiovascular diseases is controversial. R...
Peer-assisted HIV partner notification services to strengthen index partner testing for newly diagnosed men who have sex with men in coastal Kenya
Background HIV partner notification services (PNS) have been proven safe and effective in finding undiagnosed HIV infections among general populations in settings with high HIV incidence, but have not...
Exploring the impact of classroom climate on music aesthetic literacy in nonmusic majors
This study explores the impact of the classroom climate, encompassing both the physical environment (PE) and teacher–student interactions (TSI), on music aesthetic literacy (MAL) among nonmusic-major...
Pathways to effective network governance: A fuzzy-set QCA study of tripartite collaboration efficiency with Chinese official Weibo data
In response to the insufficient research on multiagent collaboration mechanisms in existing network governance studies, this paper identifies the key influencing factors of the tripartite collaboratio...
Utilization of varenicline among Kansas Medicaid enrollees
Background Smoking prevalence among Medicaid beneficiaries is twice that of privately insured adults, yet effective smoking cessation treatments remain underutilized. Understanding varenicline use, th...
Oral microbiome dysbiosis in acute ischemic stroke and transient ischemic attack patients
Oral microbiome (bacterial community) may influence systemic inflammation and vascular health, which both are critical factors in a pathogenesis of ischemic stroke. This study aimed to evaluate differ...
Comparison between random and convenience samples in a multicenter survey to evaluate medical students’ quality of life
Evaluating medical students’ mental and physical health is challenged by difficulties in obtaining randomized samples and the limitations of convenience samples. We conducted a multicenter study to as...