PLoS ONE
Articles in this Issue
Special histological subtypes of breast cancer in a Hispanic Latino population
Introduction Special histologic subtypes of breast cancer have a unique biological behavior and outcomes. The literature has demonstrated that histologic and phenotype subclassification of breast canc...
Comparison of diagnostic algorithms used in guidelines on nutritional anaemias in adults
Background Anaemia is highly prevalent and commonly caused by nutritional deficiencies. Guidelines often include an algorithm to find the underlying cause. Here, we compared diagnostic algorithms and...
Low systemic vascular resistance with normal blood pressure: Do we need vasopressors?
Background Vasoplegia is defined by systemic vascular resistance (SVR) < 800 dynes·s/cm5, cardiac index (CI) > 2.2 L/min/m2, and hypotension, and is associated with poor outcomes. Maintaining ad...
Patterns and impacts of patient migration for primary knee arthroplasty in China: A national retrospective study
Objective The phenomenon of interregional patient migration for primary knee arthroplasty (KA) appeared due to unbalanced distribution of medical resources. However, there is a paucity of literature a...
Healthcare providers’ experiences and recommendations for antiretroviral therapy adherence in Ghana: A facility-based phenomenological study
Background In Ghana, poor treatment adherence among persons living with HIV (PLHIV) affects the effective treatment and management of HIV/AIDS. A key limitation in addressing the antiretroviral therap...
Unveiling the full picture of malnutrition in Sub-Saharan Africa: The extended composite index of anthropometric failure among children under-5 in the SDG era
Introduction The burden of malnutrition among children under-5 in Sub-Saharan Africa (SSA) remains a significant public health concern. Traditional indices such as stunting, wasting, and underweight o...
Incidence and prevalence of neurodevelopmental disorders and disabilities among métis children in Alberta, Canada: A retrospective birth cohort study
Limited research has examined the neurodevelopmental health of Métis children from a functional perspective, which is essential for culturally sensitive service planning, and policy development. This...
Vehicle rescue path planning for urban traffic waterlogging disaster based on GAST model
Rescue transportation will be severely hindered under urban waterlogging disasters. To solve the problem of delayed rescue of disaster vehicles, this study is based on a hydrodynamic model and uses a...
Variety-specific selenium accumulation patterns and quality attributes of rice following foliar selenium application
In the context of addressing regional selenium (Se) deficiencies in China, this study undertook an investigation into the efficacy of foliar Se spray on 12 rice varieties. The primary focus was on ass...
Integrating feature importance techniques and causal inference to enhance early detection of heart disease
Heart disease remains a leading cause of mortality worldwide, necessitating robust methods for its early detection and intervention. This study employs a comprehensive approach to identify and analyze...
Association of serum intestinal fatty-acid binding protein, inflammatory and oxidative stress markers with colorectal cancer among Ghanaian patients
Background In sub-Saharan Africa, colorectal cancer (CRC) is becoming an increasingly serious public health issue. However, little is known about the relationships between inflammation, oxidative stre...
Strengthening evidence for text-based telehealth in post-operative care: A pragmatic study of the reach and effectiveness of two-way, text-based follow-up after voluntary medical male circumcision in South Africa
Building upon evidence of safety and efficiency gains from a randomized control trial (RCT) in South Africa, we further scaled implementation of two-way, short message service (SMS), text-based (2wT)...
Diffusion-based skin disease data augmentation with fine-grained detail preservation and interpolation for data diversity
We propose a data augmentation technique utilizing a Diffusion-based generative deep learning model to address the issue of data scarcity in skin disease diagnosis research. Specifically, we enhanced...
Neural correlates of the deployment of spatial attention, and their modulation by repetitive movements
The deployment of spatial attention generates distinct neural signatures that can be detected at the scalp. Here, we use multivariate pattern analysis of EEG data to decode the deployment of spatial a...
Exploring the molecular and biological mechanisms of host response in chickens infected with highly pathogenic avian influenza virus (H5N1): An integrative transcriptomic analysis
The H5N1 strain of highly pathogenic avian influenza (HPAI) has raised worldwide alarm, posing a threat to the health of both animals and humans. The study aimed to identify key genes and biological p...
Nummi Digitali: A pioneering multimodal platform for numismatic heritage
This work presents a pioneering multimodal platform designed for the study, cataloging, and dissemination of numismatic heritage: “Nummi Digitali”. This ecosystem enables a web-based structured record...
Reduced complications and mortality after admission for head and neck cancer in patients with previous dental scaling: a retrospective cohort study based on real-world data
Background The association between oral health and cancer outcomes remains unclear. The purpose of this study was to evaluate the complications and mortality after admission of head and neck cancer (H...
Environmental enrichment as a therapeutic strategy against methamphetamine induces depressive behaviors in mice
Methamphetamine (METH) abuse is associated with addiction, emotional dysregulation, motor impairments, cognitive deficits, and depressive symptoms, which are exacerbated by stress and social isolation...
Clinical & laboratory profiles and treatment outcome of Kawasaki disease in children: Experience from a tertiary care hospital
Background A total of 40 cases of Kawasaki Disease (KD), diagnosed & categorized on the basis of criteria set by the American Heart Association were studied. We sought to evaluate their clinical a...
Energy expenditure and enjoyment of instructor-led exercise videos for children ages 7–13
Background The Interrupting Prolonged sitting with ACTivity (InPACT) at Home intervention provides youth with access to virtual, instructor-led exercise videos to promote physical activity in the home...
Understanding social inclusion: A directed content analysis
Background Social inclusion can be defined as a process that enhances opportunities for social participation, strengthens social bonds, and ensures equitable access to opportunities and decision-makin...
Evaluation of the antidiarrheal activity of dichloromethane-methanol crude extract of the aerial parts of Croton kinondoensis (Euphorbiaceae) in Mice
Background Diarrhea remains a major global health concern, particularly in developing countries. Resistance to conventional antibiotics underscores the need for effective, plant-based alternatives. Cr...
Dementia as a risk factor for 30-day mortality in community-acquired pneumonia in Colombia (CAP): A survival study
Background Community-acquired pneumonia (CAP) represents a significant clinical challenge, particularly in patients with comorbidities, such as dementia, which increases the risk of mortality and hosp...
Experiment study on the cross-layer propagation characteristics of hydraulic fracturing cracks in coal roof rocks
Fracture of the overlying roof of a coal seam has become the main method to increase the permeability of coal seam in coalbed methane exploitation. Because the fracture must grow into the coal and thr...
GEOTrat Points as a free resource in QGIS for mapping the performance of agricultural experiments
Agricultural experimentation requires careful selection of the experimental design and model for analyzing treatment data. However, even with rigorous experimental control, the discrepancies between t...