PLoS ONE
Articles in this Issue
Formulation and validation of a regional household wealth index for sub-Saharan Africa
A new era in global health assistance requires a focus on efficiently using limited and declining donor funds. This shift requires better evaluation methods to allocate resources effectively. Most eva...
DNA barcoding for elasmobranch diversity assessment in Thailand: Its advantages and limitations
The assessment of elasmobranch biodiversity in Thailand benefits greatly from the application of DNA barcoding, which helps mitigate the challenge posed by a shortage of expert taxonomists. Fragments...
More than half a century of evolutionary studies in Rhodnius prolixus Stål, 1859 (Hemiptera, Triatominae): revisiting and discussing old and new data on intra- and interspecific reproductive barriers
Rhodnius represents a paraphyletic group, being R. prolixus one of the most...
Exposure to volatile organic compounds increases the risk of sarcopenia: Insights into association and mechanism
Background Volatile organic compounds (VOCs) are ubiquitous in our environment, and their associations with sarcopenia are unknown. The aim of this study is to evaluate the associa...
The association between the CUN-BAE index and depression mediated by SIRI: A large cross-sectional study
Background Depression is a common global mood disorder problem and one of the major disabling factors. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index i...
Qualitative understandings of the persistent use of traditional contraceptive methods using the socio-ecological model among older reproductive-age women in Khulna, Bangladesh
Background The continued use of Traditional Contraceptive Methods (TCM) among Bangladeshi women of reproductive age (aged 35–49 years) poses a significant public health issue. Exis...
Health effects of street vended fresh cut fruits: A randomized controlled trial in Bangladesh
Foodborne infections, particularly from street-vended fresh-cut fruits, are a growing public health concern in urban settings of developing countries. This study evaluated the gastrointestinal effects...
Bone weathering in a Mediterranean climate region: An experimental case study from Doñana National Park (Spain)
Bone weathering constitutes a highly informative and commonly studied variable in taphonomic analyses. Vertebrate paleontologists, zoo-archeologists and forensic anthropologists have used weathering a...
Reliable evaluation for the AI-enabled intrusion detection system from data perspective
As the primary link in cybersecurity, the intrusion detection system (IDS) is of indispensable importance. Many studies have proposed sophisticated artificial intelligence (AI) models to detect intrus...
In-Silico discovery of Pediatric Acute-Myeloid-Leukemia (pAML) causing druggable molecular signatures highlighting their pathogenetic processes and therapeutic agents through single-cell RNA-Seq profile analysis
Pediatric acute-myeloid-leukemia (pAML) is an aggressive malignancy and the second most common blood cancer in children. In spite of significant advances in the frontline therapeutic approaches, appro...
Construction of a prognostic prediction model for concurrent radiotherapy in cervical cancer using GEO and TCGA databases with preliminary validation analysis
Introduction Radiotherapy is a primary treatment for intermediate and advanced cervical cancer (CC). Resistance to radiotherapy is a principal reason for treatment failure in synch...
Optimizing blood alcohol concentration measurement with breath alcohol meter and its preliminary application in evaluating CYP2E1 activity
Background Ethanol metabolism in vivo is primarily mediated by CYP2E1 and alcohol dehydrogenase, with CYP2E1 play...
Comparative mortality outcomes in metabolic dysfunction-associated steatotic liver disease and nonalcoholic fatty liver disease subtypes in the United States
Background In 2023, experts from the European and American regions proposed the concepts of steatotic liver disease (SLD) and metabolic dysfunction-associated steatotic liver disea...
One SQ HEDGES DNA vector only dose produces durable hGLA or anti-SARS-CoV-2 mAb therapeutic serum protein levels
It is estimated that ~2 billion people worldwide cannot afford even basic medicines. B ioreactor-produced r ecombinant...
Correction: Image recognition technology for bituminous concrete reservoir panel cracks based on deep learning
Effect of imeglimin on metabolic dysfunction-associated steatotic liver disease in individuals with type 2 diabetes
Objective Preclinical studies, including animal and in vitro experiments, have suggested that imeglimin, a novel antidiabetic drug, may have beneficial effects on metabolic dysfunc...
Matching of XEN®45 and PRESERFLO™ MicroShunt cases: Outcomes of a 3-year follow-up
Objective To compare long-term outcomes of XEN®45 (XEN) and PRESERFLO™ MicroShunt (PRESERFLO) implants in the surgical management of glaucoma over a 3-year follow-up period, focusi...
Development and validation of an asthma self-knowledge questionnaire
Background Validated questionnaires for adequately assessing knowledge about asthma are scarce. Thus, the primary objective of the present study was to develop and validate an asth...
Scenario evolution modeling and probabilistic assessment of seawater intrusion accident in ports: An integrated framework combining disaster theory and multi-method simulation
As a typical marine disaster, seawater intrusion accidents have posed a serious threat to port production safety due to the double rise in the occurrence frequency and damage intensity. In favor of ef...
Correction: Associations of self-reported hearing problems with long-term trajectories of mental and functional health in middle-aged and older adults: The role of self-perceptions of aging
Utilization of interdisciplinary in-hospital early rehabilitation in COVID-19 patients - a multicenter cohort study in the National Pandemic Cohort Network (NAPKON) in Germany
Background Early rehabilitation in acute hospitals aims to prevent immobilization-related complications and improve the functional capacity of patients with severe or critical illn...
Evaluation of the new blood-pool CT contrast agent VivoVist in mouse models
Small animal CT imaging provides high resolution imaging of bone structure, lungs, and gross anatomy. However, it is limited in its ability to provide high soft tissue contrast. Several blood pool CT...
Association between serum vitamin D deficiency and visceral fat indices in adolescents: The Ewha Birth and growth cohort study
Purpose Vitamin D plays a crucial role in cardiometabolic health, but its association with visceral fat in adolescents remains unclear. This study aimed to evaluate the relationshi...
Effect of semen dilution rate and dimethyl acetamide levels on post-thaw motility and fertility parameters of rooster sperm
This study evaluated the impact of pre-freezing semen dilution rate and dimethyl acetamide (DMA) concentration on the post-thaw motility and fertility of cryopreserved rooster sperm. Rooster ejaculate...
Association of health behaviors with healthcare workers’ physical and psychological well-being: Learning from the COVID-19 pandemic
Background During the COVID-19 pandemic healthcare workers reported using a variety of positive or negative health behaviors as a strategy to cope with the increased stress at work...