PLoS ONE
Articles in this Issue
Preferences for cesarean section among pregnant women at a tertiary hospital in Ho Chi Minh City, Vietnam: Influencing factors and implications for prenatal care
The World Health Organization recommends a cesarean section (CS) rate of 10–15%. However, global rates may increase to 29% by 2030, raising concerns about the potential overuse of CS without medical i...
Olanzapine-induced metabolic syndrome is partially mediated by oxytocinergic system dysfunction in female Sprague-Dawley rats
Introduction Olanzapine (OLZ), a second-generation antipsychotic, is associated with the development of metabolic syndrome with unclear underlying pathophysiologic mechanisms. Oxyt...
Self-learning model fusion for network anomaly detection: A hybrid CNN-LSTM-transformer framework
The rapid evolution of cyber threats poses significant challenges to the adaptability and performance of anomaly detection systems. This study presents an innovative hybrid deep learning framework tha...
Isolation, identification, and whole-genome sequencing of Streptomyces rochei FE-3-1 against Pyricularia oryzae
Streptomyces are significant producers of antimicrobial secondary metabolites. In this study, a Streptomyces rochei...
Exploring the state of evidence on aging with HIV in long-term care: A scoping review protocol
Background The growing population of older adults living with HIV presents unique challenges for long-term care facilities, which are increasingly tasked with supporting residents...
Determinants of place of death among individuals with cardiovascular disease: A Saudi sub-national register study
Understanding the place of cardiovascular disease (CVD) deaths is essential for identifying vulnerable populations and guiding health system interventions. This study investigated the demographic and...
Social isolation and cardiometabolic burden synergistically predict physical dysfunction in aging Chinese adults: Evidence of risk thresholds and the mediating role of frailty
Objective This study aimed to investigate the independent and synergistic effects of social isolation and multidimensional biomarkers (cardiovascular, metabolic, renal, muscular, a...
Correlates of food insecurity among university students in a socioeconomically disadvantaged area of the Paris suburbs: A cross-sectional study
Background Despite increasing political and scientific interest in food insecurity (FI) among higher education students, data for Europe remain scant. We assessed the prevalence of...
Impact of histone post-translational modification inhibitors on lifespan, reproduction, and stress response in the rotifer Brachionus manjavacas
Epigenetic modifications, including histone post-translational modifications, are central drivers of age-associated structural and functional changes in the genome, influencing gene expression and lea...
Prevalence and risk factors of hypertension among clients seeking care at Selected Healthcare Facilities in Kenya
Background Hypertension remains one of the primary risk factors for cardiovascular disease and the leading cause of mortality worldwide. According to the World Health Organization...
Validation of the human disharmony loop: Pectoralis minor tenotomy significantly reduces pain and improves function in historically challenging patients who meet reproducible and explicit diagnostic criteria
Background/Objectives Patients commonly present with a mix of intractable shoulder pain, persistent impingement/loss of shoulder motion, neck pain, headaches, and distal neuropathy...
Short term hemodynamic effects of atrial fibrillation in a closed-loop human cardiac-baroreflex system
Atrial fibrillation (AF) remains the leading cardiac cause of stroke and AF-related death rate in the United States has been increasing for over twenty years. While the effect of standalone AF on hear...
The impact of industrial digitalization on the urban-rural income gap
Along with the rapid development of the global digital economy, China is experiencing profound transformations in industrial digitization. These transformations may significantly affect the urban-rura...
Evaluating voter perceptions of political party similarity: A mixed-method study of party positions in Taiwan
This study examines voter perceptions of political party similarity using data from a validated online survey conducted in Taiwan. It primarily collects qualitative data through open-ended questions,...
Small-scale experimental and numerical simulation of blasting in jointed rock-like materials under varied joint and explosive conditions
This study focuses on the blasting failure of rock-like materials, aiming to investigate the effect of the joint spatial characteristics and explosive parameters. Rock mass blasting is complex, and th...
Gene editing of the thioester reductase step in the biosynthesis of lysergic acid amides
Ergot alkaloids derived from lysergic acid are important in agriculture, as food and feed contaminants, and in medicine, as the foundation of several pharmaceuticals. The fungus Me...
DCAF-GAN: Enhancing historical landscape restoration with dual-branch feature extraction and attention fusion
Historical landscape restoration has become a crucial area of research in cultural heritage preservation, and with the advancement of digital technologies, effectively restoring damaged historical ima...
Cardiovascular disease detection: A hybrid machine learning-AI framework for personalized diagnosis and risk assessment
Cardiovascular disease (CVD) is considered the number one killer disease in the world, underlining the importance of the application of more accurate diagnostic and therapeutic tools. Traditional scre...
A stochastic wideband propagation-graph channel model for plants-affected drones air-to-ground mmWave communications
Unmanned aerial vehicles (UAVs) are experiencing extensive worldwide application across various fields, particularly in outdoor scenarios that often involve vegetation. A comprehensive understanding o...
Phenotypic profiling of small molecules using cell painting assay in HCT116 colorectal cancer cells
Understanding how small molecules affect cellular morphology is essential for exploring their mechanisms of action (MoA) and identifying new therapeutic candidates. In this study, the Cell Painting As...
The effect of different structural decoration geometries on vibration propagation in spider orb webs
The stabilimentum, or structural decoration, in spider orb webs is a fascinating structure. While the species that construct stabilimenta and their building techniques are well-documented, the precise...
Start up: A French program to support patients with pulmonary arterial hypertension during the adjustment of prostanoids to the individualized optimal dose
The Start Up program was initiated in patients with pulmonary arterial hypertension (PAH) with the objective to support them in taking their therapies targeting the prostacyclin pathway and determine...
Functional expression of a Mo-dependent formate dehydrogenase in Escherichia coli under aerobic conditions
Background Oxygen tolerant complex metal-dependent formate dehydrogenases hold potential for biotechnological applications....
Correction: Prevention and inhibition of post-harvest browning in longkong pericarp using Prunus Persica resin coating during ambient storage
Beyond the game: How social interaction and emotional gratification drive Chinese sports podcast engagement
The rapid growth of podcasting platforms has transformed digital media consumption, offering diverse content tailored to user preferences. The present research aims to identify the needs associated wi...