PLoS ONE
Articles in this Issue
Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples
Homologous recombination repair (HRR) is a cellular pathway for high-fidelity double strand DNA break repair that uses the sister chromatid as a guide to ensure chromosomal integrity and cell viabilit...
The effect of antenatal psychological well-being on maternal health status
Background The presence of psychological pressures may negatively affect the health of pregnant women pre-, during, and post-childbirth and may lead to many complications....
Transcriptomics insights into the functional role of tick Ixodes ricinus proteins metalloprotease and antigen p23
Ixodes ricinus ticks (Acari: Ixodidae) are hematophagous ectoparasites and a major European vector of zoonotic diseases affecting global health. Tick salivary...
Effect of functional badminton games on basic motor skills and sensory integration in 5–6-year-old preschool children: A randomised controlled trial
Objective This study aimed to develop functional badminton games for preschool children and investigate their efficacy in promoting basic motor skills and sensory integration....
Can telemedicine help integrate the referral-based healthcare system? An economic and operational analysis
Purpose Telemedicine can help specialists in providing efficient care to patients from a distance and it has been growing steadily in healthcare. This study aims to provide an oper...
Personalized lead exposure information and preventive behaviors in Ivory Coast: Insights from a pilot study
Lead (Pb) exposure is a major global health concern, particularly for young children, yet awareness of the risks is low. Pb-based paint remains a significant source of exposure in many low- and middle...
A comparative study on folk sports inheritance in China and South Korea: Influencing factors and mediating roles
This study investigates the similarities and differences in the factors influencing folk sports inheritance in China and South Korea, providing a theoretical foundation for fostering bilateral learnin...
Perceptions and experiences of older adults in a youth community health volunteer–led health coaching program in Singapore: A qualitative study
Background With an aging global population, there is a growing emphasis on community-based approaches to preventive health for older adults. While Community Health Volunteers have...
MRI-based 2.5D deep learning and radiomics effectively predicted microvascular invasion and Ki-67 expression in hepatocellular carcinoma
Objective To develop and validate an integrated 2.5D deep learning (DL) and Radiomics model using gadoxetic acid-enhanced MRI hepatobiliary phase (HBP) images combined with clinica...
Saudi adolescents’ perceptions of dietary contributions to obesity: A qualitative study
Background Adolescents’ perceptions of the dietary effects of obesity play an imporant part in shaping their eating behaviors, lifestyle choices, and overall health outcomes. Their...
Enhancing sarcasm detection on social media: A comprehensive study using LLMs and BERT with multi-headed attention on SARC
Sarcasm detection in natural language processing (NLP) remains a complex challenge, especially in social media, where contextual clues are often subtle. This study addresses this challenge by leveragi...
Deepfake defense: Combining spatial and temporal cues with CNN–BiLSTM–transformer architecture
The proliferation of deepfakes is a major threat to the believability of online media and the stability of public discourse. These hyper-realistic fake videos, nearly indistinguishable from genuine co...
Improved brain tumor diagnostics and follow-up with novel magnetic resonance imaging methods: A single center study protocol
This protocol outlines a prospective study aimed at enhancing the diagnosis and monitoring of brain tumors through advanced non-invasive imaging techniques. While magnetic resonance imaging (MRI) is a...
Monitoring arts and psychomotor therapies: Further development and validation of the Self-expression and Emotion-Regulation in Arts and Psychomotor Therapies Scale (SERAPTS)
Background The present study is an extension of previous research, which resulted in the development of a valid, reliable and user-friendly tool for monitoring art therapy. The pur...
Design and experiment of a novel intelligent device suitable for automation vegetable plug seedling
To tackle the challenges of high manual labor intensity and low efficiency in traditional vegetable plug seedling processes, this study developed an automated mechanical device through innovative desi...
The coupling and coordination degree and driving mechanism of water and land resources in the Beijing-Tianjin-Hebei urban agglomeration
Against the background of sustainable development, the use and development of water and land resources have become focal topics. In this study, the entropy method, Vector Autoregression (VAR), and the...
Correction: Reproductive health programs in women with physical disabilities: A scoping review protocol
Coverage and determinants of deworming uptake among under-five children in Somalia: A multilevel analysis of the 2020 SDHS data
Background Soil-transmitted helminth (STH) infections are a major public health concern in Somalia, particularly affecting the health and development of children under five. Theref...
Predictors of active ageing among older adults in age-friendly communities in Yanji City, China: A cross-sectional study
Background With the global population ageing rapidly, especially in China, promoting active ageing is crucial for ensuring healthy longevity. However, limited studies have examined...
Genome analysis of Actinobacillus pleuropneumoniae strain APPFJLYC01 reveals multidrug resistance and high virulence potential
Actinobacillus pleuropneumoniae is the primary etiological agent of porcine contagious pleuropneumonia, a devastating respiratory disease that causes substanti...
Glyphosate treatments for managing successional dynamics in beech bark disease-affected northern hardwood forests
The spread of beech bark disease (BBD) in northern tolerant hardwood forests poses a significant forest management challenge. Extensive aboveground mortality in BBD-affected stands often leads to the...
Phytochemicals and antioxidant activity of leaf extract and callus cultures of Cinnamomum camphora L
Cinnamomum camphora L. is highly significant landscape tree known for its medicinal values and presence of secondary metabolites that have antioxidant, antimic...
Do children allocated to different methods of complementary feeding introduction have distinct food preferences and flavor acceptance in the first years of life? A randomized clinical trial
This study aimed to analyze the food preferences and flavor acceptance among children allocated to different methods of complementary feeding (CF) introduction in the first years of life. This randomi...
Spatiotemporal evolution, regional disparity, and driving factors of county-level rice production carbon efficiency: A case study of Jiangxi Province, China
Accurately quantifying the carbon efficiency of rice production (RCE) and elucidating its spatiotemporal evolution, regional disparities, and driving factors hold significant theoretical and practical...
The multisystemic roots of South African child and youth resilience: A scoping review
Introduction and objective A multisystemic approach to researching resilience investigates resources across multiple systems, including biological, psychological, social, instituti...