PLoS ONE
Articles in this Issue
Diagnostic concordance of GeneXpert HCV VL fingerstick and GeneXpert HCV viral load with RT-PCR in POCT settings among hemodialysis patients
Background Hepatitis C virus (HCV) remains a significant global health concern, particularly among high-risk populations such as patients undergoing hemodialysis. Although nucleic...
Has anything changed for Fibromyalgia? Focus groups with patients on their lived experiences in England
Background While awareness of Fibromyalgia (FM) has evolved across healthcare and social settings, individuals with FM continue reporting poor understanding of their condition in t...
Parenterally administered pegbovigrastim alters leukocyte counts, granulocyte functions, and uterine cell population in healthy postpartum dairy cows
This study aimed to evaluate the effects of a single postpartum administration of pegbovigrastim, a recombinant bovine granulocyte colony-stimulating factor (rG-CSF), on peripheral leukocyte profiles,...
Health-related effects of walking football in older adults: A real-world longitudinal study across a season comparing two age groups
The aim of the study was to evaluate the health-related effects of a 9-month walking-football (WF) season in already active older adults, comparing participants aged 50–59 and ≥60. The study employed...
Association between hospital frailty risk score, risk of sepsis and adverse outcomes across all adult ages
Background Hospital Frailty Risk Score (HFRS) is commonly used to identify frailty risk and predict poor outcomes. Frailty and sepsis are associated with poor outcomes. This study...
Landscape-level effectiveness of fuel treatments in a forest-dominated ecosystem in the Southern United States
Wildfire has become an increasing threat to natural ecosystems and human livelihood alike in many parts of the world. Vegetation fuel treatments are considered a viable option for mitigating wildfire...
Association of body mass index on sexual function in women with endometriosis: A cross-sectional study
Objective This study aimed to investigate the association between body mass index (BMI) and sexual function, measured by the Female Sexual Function Index (FSFI), in women with endo...
MetaMind: A multi-agent transformer-driven framework for automated network meta-analyses
Background Network meta-analysis (NMA) can compare several interventions at once by combining head-to-head and indirect trial evidence. However, identifying, extracting, and modell...
Shared leadership and project success: The mediational role of individual- and team-related factors
The existing research on the role of shared leadership in achieving project success is rudimentary but suggests that this role may be important. In this study, we examined the relationship between sha...
Digital literacy: The catalyst for credit access and income growth in rural households
To clarify the role of digital literacy improvement in farm household income growth, this paper constructs a digital literacy assessment framework covering seven dimensions and uses data from a 2023 r...
Precision screening identifies mitoxantrone as a multitarget inhibitor in ageing-associated cancers with extensive computational validation and doxorubicin comparison
Ageing-associated cancers are characterised by the dual hallmarks of persistent DNA damage and the ability of tumour cells to escape senescence checkpoints, which drive genomic instability and uncontr...
Machine learning-based on model for explain risk of 24-hour death in critically ill patients in the prehospital setting: A retrospective cohort study
This study aimed to develop and validate a machine learning-based model for predicting 24-hour mortality in critically ill patients using prehospital and admission clinical data. We conducted a retros...
Identifying avian influenza hotspots in wild birds in the Netherlands
Highly Pathogenic Avian Influenza (HPAI) threatens wild and domestic birds, mammals, and humans. The global spread of HPAI through wild birds requires timely, spatially accurate detection for enhanced...
Pore structure and fractal characteristics of deep shale gas reservoirs in the Western Chongqing block, Sichuan Basin
To date, researchers have not systematically investigated the geological characteristics of deep shale gas reservoirs in the Western Chongqing Block. Furthermore, the single technique remains insuffic...
Correction: Personality is predictive of burnout but not of work engagement: A one-year prospective cohort study
Nationwide epidemiological study of tuberculosis and other respiratory pathogens among children and adolescents in Brazil: TBPed Brazil study protocol
The burden of lower respiratory tract infections (LRTIs) caused by Mycobacterium tuberculosis (MTB) among children and adolescents is often underestimated due t...
Retraction: Molecular mechanism of inhibitory effects of melatonin on prostate cancer cell proliferation, migration and invasion
Influence of the tumor microenvironment on genetic mutations in thyroid carcinoma
In contrast to cancers with high immunotherapy responsiveness, such as lung cancer and melanoma, thyroid carcinoma (THCA) immunotherapy remains investigational. To establish a theoretical foundation f...
Does menopause influence the association between atherogenic index of plasma and prediabetes? A cross-sectional study in middle-aged Chinese women
Background The atherogenic index of plasma (AIP) is a novel marker associated with the risk of prediabetes, yet its interplay with menopausal status remains unclear. This study aim...
Exploration and discovery of treatment targets for primary biliary cholangitis based on plasma and cerebrospinal fluid proteomics: A multicenter mendelian randomization study
Background Primary biliary cholangitis (PBC) is a chronic, progressive autoimmune cholestatic liver disease. Current first-line therapy, ursodeoxycholic acid (UDCA), yields subopti...
Resilient distributed model-free adaptive traffic signal control via controller dynamic linearization under DoS attacks
The increasing complexity and persistent network security challenges in traffic signal control are key issues requiring urgent attention to meet growing traffic demands. To address these issues, this...
ECE-VDTDA: A robust and computationally efficient collision avoidance system for driver assistance in foggy weather
Advanced Driver Assistance Systems (ADAS) and Collision Avoidance Systems (CAS) are the primary modules of modern human-centric and autonomous driving applications, such as forward and rear-end collis...
Al18F-NOTA-FAPI-04 PET/CT for diagnosis of breast cancer and its correlation with pathological features: A single-center retrospective study
Objective To systematically evaluate the diagnostic efficacy of Al¹⁸F-NOTA-FAPI-04 PET/CT in breast cancer and explore the correlation between tracer uptake parameters and patholog...
Correction: Thorax temperature and niche characteristics as predictors of abundance of Amazonian Odonata
A modular and interpretable framework for tabular data analysis using LLaMA 7B: Enhancing preprocessing, modeling, and explainability with local language models
Predicting whether a patient will attend a scheduled medical appointment is essential for reducing inefficiencies in healthcare systems and optimizing resource allocation. This study introduces a loca...