PLoS ONE
Articles in this Issue
Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol
Background Oral mucositis is a frequent adverse effect of chemotherapy that significantly affects patients’ quality of life and treatment continuity. Despite its clinical relevance...
Private garden uses and associated mental well-being benefits during the first UK Covid-19 lockdown – a social media investigation
During the UK’s first national Covid-19 lockdown in spring 2020, people had greatly diminished access to public green spaces due to government restrictions. This provided an opportunity to investigate...
Evaluation of diversity and effective traits in Iranian cotton germplasm
Drought is one of the most important abiotic factors influencing crop development and productivity. As a result, there is a need to enhance cultivars with high compatibility and low water requirements...
A secret from a hidden world: A new glassfrog of the genus Nymphargus (Anura: Centrolenidae) from Cordillera del Cóndor, Ecuador
The genus Nymphargus is the most speciose of the family Centrolenidae with 44 species. In this study, we describe a new species of Nymphargu...
Quality of informal care among informal caregivers of people with dementia: A latent profile and ROC analysis
Background The quality of informal care for people with dementia (PwD) has gained increasing importance, as most PwD prefer home-based care over institutional placement. However, e...
Retraction: Application of artificial bee colony algorithm based on homogenization mapping and collaborative acquisition control in network communication security
Rural first-mile pickup and last-mile delivery: A bus-assisted heterogeneous-drone model
With the rapid expansion of rural e-commerce, widely dispersed demand and limited road infrastructure have made conventional truck-based first-mile pickup and last-mile delivery increasingly unsustain...
Analytical validation and clinical evaluation of a high-sensitivity cardiac troponin I immunoassay for use in cats
Cardiac troponin I (cTnI) is a cardiac specific biomarker of myocardial damage in humans, dogs, and cats. The ADVIA Centaur XP High-Sensitivity Troponin I assay (AC-cTnI-HS) has been validated for use...
Retraction: Optimizing chemotherapeutic targets in non-small cell lung cancer with transfer learning for precision medicine
AI-assisted optimization design of seismic performance parameters for timber structures
Timber multi-story buildings offer environmental benefits, lightweight construction, and seismic resilience, but Artificial Intelligence (AI) based integrated frameworks for optimizing seismic paramet...
Farm scale on the transformation of agricultural mechanization services:Evidence from China
Understanding the dynamics of agricultural mechanization services is essential for fostering the sustainable development of grain production in countries where small-scale farming predominates. This s...
Correction: Symmetry, presumptions, and the judges design
Microbial diversity, functional genomics and antibiotic resistance in integrated chicken and fish farming systems of Bangladesh
The integrated chicken and fish farming system in Bangladesh is widely practiced for its resource efficiency, yet its microbial structure, functional potential, and associated antimicrobial resistance...
Correction: E2SVM: Electricity-Efficient SLA-aware Virtual Machine Consolidation approach in cloud data centers
Protocol: A multi-factorial, multi-centre study, for biomarker identification in healthy controls for comparison to babies with moderate-severe NESHIE
Neonatal encephalopathy suspected to be hypoxic-ischaemic encephalopathy (NESHIE) remains a leading cause of neonatal mortality and long-term neurodevelopmental impairment, particularly in low- and mi...
A transfer-aware, deployment-oriented evaluation framework for NetFlow-based intrusion detection systems (TAN-IDS)
Machine learning-based Intrusion Detection Systems (IDS) often report high detection accuracy under controlled, single-dataset evaluation, yet experience severe performance degradation when deployed i...
Association of marital and parental status with stress, support, adherence, and quality of life among breast cancer women
Backgrounds Breast cancer presents multifaceted challenges that extend beyond physical illness, profoundly influencing patients’ psychological well-being, treatment adherence, and...
Comparative analysis of text readability and writing styles in AI-generated vs. Human-written academic abstracts
Research article abstracts are vital in scientific publications for readers to assess a study’s significance. The increasing use of AI tools, such as Kimi, ChatGPT and DeepSeek, to generate abstracts...
Animal abuse by falsification–Recognition amongst the veterinary profession in The Netherlands
Presently, Animal Abuse by (condition/ illness) Falsification (AAF), has received little scientific attention. Feigning illness in children for attention purpos...
Developing and validating a measure of L2-specific emotion regulation strategies
Background Despite recent scholarly interest in the regulation of academic emotions in second language (L2) learning, L2 studies have primarily relied on domain-general instruments...
Engineering exosomes with iRGD for targeted RNAi therapy against pancreatic cancer mediated by long non-coding RNA PLBD1-AS1
Tumor-derived exosomes play critical roles in pancreatic ductal adenocarcinoma (PDAC) progression by mediating intercellular communication within the tumor microenvironment. This study identifies the...
Leprosy neuropathy and demyelinating impairment: How should we interpret this neurophysiological pattern?
Introduction/Aims Leprosy neuropathy (LN) may cause demyelination that worsens during the leprosy reactions (LR). Type-1 LR (T1LR) occurs in patients with ce...
A new experimental method for evaluating the effectiveness of auditory signals under realistic background noise conditions: A randomized controlled pilot study
This study introduces a new experimental method for analyzing auditory signals in the presence of background noise and identifying sounds that are consistently easy for humans to notice in daily envir...
White matter microstructure disruption associated with PET and cognitive impairment in Alzheimer’s disease
Alzheimer’s disease (AD) is associated with regional brain atrophy as well as elevated positron emission tomography (PET) markers of amyloid-beta (e.g., [¹⁸F]florbetapir (FBP)) and tau protein (e.g.,...
Energy collaborative optimization of power routing based on PPO and generative adversarial imitation learning
Under the general trend of global energy transformation, the proportion of renewable energy in the power sector continues to increase. Power routers are of great significance for improving energy util...