PLoS ONE
Articles in this Issue
Adherence to antiretroviral therapy and its associated factors among children living with HIV in Eastern and Southern Africa: A systematic review and meta-analysis
Background Children living with HIV in low-income settings, such as in Eastern and Southern Africa, are at a high risk for poor adherence to antiretroviral therapy. However, various primary studies pr...
Are the 2009 Institute of Medicine gestational weight gain recommendations applicable in a contemporary South-East Asian pregnancy cohort? Results of a prospective analysis
Gestational Weight Gain (GWG) modulates pregnancy outcomes and long-term offspring metabolic health. The 2009 Institute of Medicine (IOM) GWG recommendations have largely been validated in Caucasian a...
Revising the definition of “demand satisfied for modern methods of family planning:” A cross-sectional study to explore incorporating person-centered constructs of demand, choice, and satisfaction
Several challenges to validity have been identified with standard approaches used to measure “demand satisfied for modern methods of family planning.” This study explored construct validity of the wid...
Dialysate and plasma meropenem concentrations in continuous intraperitoneal regimen during peritoneal-dialysis-related peritonitis
Background A single dose of intraperitoneal (IP) meropenem is recommended for peritoneal-dialysis (PD)-related peritonitis stemming from extended-spectrum β-lactamase-producing organisms. However, dat...
The synergistic effects of microcredit access and agricultural technology adoption on maize farmer’s income in Kenya
Addressing global food security demands urgent improvement in agricultural productivity, particularly in developing economies where market imperfections are perverse and resource constraints prevail....
Construction of management tools for early warning of prevacuum steam sterilization failure
Objective The aim of this study is to develop a set of management tools for early warning of steam sterilization failure, including a failure risk checklist and a calculation model for assessing early...
Effects of two training workshops upon university students’ learning of critical thinking
We evaluated the effect of two workshops on learning about critical thinking amongst first- year university students. 66 Chilean pedagogy students participated, all female, with ages ranging between 1...
Effect of case management on viral load in adult clients enrolled due to non-suppression in Capricorn District, South Africa: A case control study
Background Case management is a structured, client centered approach that incorporates various strategies such as employing lay counsellors to provide psychosocial and adherence support to strengthen...
Determining the perceptions and practices of oncologists regarding venous thromboembolism risk assessment in ambulatory cancer patients: A qualitative study
Cancer-associated thrombosis (CAT) can increase morbidity and mortality for cancer patients. Therefore, guidelines recommend predicting VTE risk and thromboprophylaxis for high-risk patients. Many stu...
Telehealth equity and access communication skills pilot simulation for practicing clinicians
Objectives This pilot study evaluated a telehealth training simulation program for practicing clinicians, specifically focused on addressing patient issues of equity and access to healthcare via impro...
Identity, language and communication concerns of subcultures: The case of Antalya Cretans
In today’s world, there is almost no homogeneous culture without interaction, and multiculturalism has become the most important phenomenon for all societies. Therefore, this cultural diversity, consi...
Energy consumption forecasting for oil and coal in China based on hybrid deep learning
The consumption forecasting of oil and coal can help governments optimize and adjust energy strategies to ensure energy security in China. However, such forecasting is extremely challenging because it...
Soil bacterial and fungal diversity and composition respond differently to desertified system restoration
Desertification is a major ecological issue worldwide that results in the destruction of terrestrial ecosystems. Restoration of desertified ecosystems has been carried out in recent decades, but the r...
NMR spectroscopy derived plasma biomarkers of inflammation in human populations: Influences of age, sex and adiposity
Understanding the distribution and variation in inflammatory markers is crucial for advancing our knowledge of inflammatory processes and evaluating their clinical utility in diagnosing and monitoring...
Persistence of Phi6, a SARS-CoV-2 surrogate, in simulated indoor environments: Effects of humidity and material properties
The SARS-CoV-2 virus caused the COVID-19 pandemic and brought major challenges to public health. It is transmitted via aerosols, droplets, and fomites. Among these, viral transmission through fomites...
Machine learning model to study the rugby head impact in a laboratory setting
The incidence of head impacts in rugby has been a growing concern for player safety. While rugby headgear shows potential to mitigate head impact intensity during laboratory simulations, evaluating it...
University students’ health-related quality of life and its determinants. Results from a cross-sectional survey during the COVID-19 pandemic
Being a university student is a vulnerable period marked by transitions and uncertainties which can impair their physical and mental well-being as well as overall quality of life. The existing literat...
Unveiling the efficacy of repetitive transcranial magnetic stimulation in Parkinson’s disease: A comprehensive review of systematic analyses
Background Many systematic reviews (SRs) have reported the repetitive transcranial magnetic stimulation (rTMS) for Parkinson’ s disease (PD), but the quality of the evidence is unclear. The aim of thi...
Individual and community-level determinants of knowledge of obstetric danger signs among women in Southern Ethiopia: A multi-level mixed effect negative binomial analysis
Introduction One of the key strategies to achieve the sustainable development goal by reducing maternal deaths below 70 per 100,000 is improving knowledge of obstetric danger signs (ODS). However, mot...
Somatization symptomology and its association with stress in patients with irritable bowel syndrome
Irritable Bowel Syndrome (IBS) patients and Somatization Symptom Disorder (SSD) patients experience somatization symptoms relative to their corresponding processes. IBS patients may also have a diagno...
Effect of the COVID-19 pandemic on colorectal cancer screening in two university-affiliated health care systems
Objectives In two large university affiliated healthcare systems, we examined trends in colorectal cancer (CRC) screening both prior to and during the COVID-19 pandemic to compare the trends in non-in...
Preventing zoonotic spillover through regulatory frameworks governing wildlife trade: A scoping review
Wildlife trade can create adverse impacts for biodiversity and human health globally, including increased risks for zoonotic spillover that can lead to pandemics. Institutional responses to zoonotic t...
Insufficient LGBTQ+ education across disciplines suggested by national survey of health professionals in training
Health professionals often feel underprepared to treat patients who identify as lesbian, gay, bisexual, transgender, and/or queer (LGBTQ+). Additionally, lack of access to professionals who are knowle...
Pain management practice and associated factors among nurses working in Ethiopia: A systematic review and meta-analysis
Background Pain management is a crucial component of patient care that promotes relaxation, lowers complications, improves quality of life, and shortens hospital stays. Several studies assessed the nu...
Chronotherapy with Cinacalcet has a striking effect on inhibition of parathyroid gland proliferation in rats with secondary hyperparathyroidism
Secondary hyperparathyroidism (sHPT) is a significant clinical complication of CKD leading to bone abnormalities and cardiovascular disease. Current treatment based on activating the parathyroid calci...