PLoS ONE
Articles in this Issue
Uncovering women’s healthcare access challenges in low- and middle-income countries using mixed effects modelling approach: Insights for achieving the Sustainable Development Goals
Background Access to healthcare services for women in low- and middle-income countries (LMICs) is crucial for maternal and child health and achieving the Sustainable Development Goals (SDGs). However,...
Antioxidative and anticancer effects of Tacca chantrieri extract enhancing cisplatin sensitivity in cholangiocarcinoma cells
Cholangiocarcinoma (CCA) poses a significant healthcare challenge due to the limited effects of chemotherapeutic drugs. Natural products have gained widespread attention in cancer research according t...
Torsion-Induced Traumatic Optic Neuropathy (TITON): A physiologically relevant animal model of traumatic optic neuropathy
Traumatic optic neuropathy (TON) is a common cause of irreversible blindness following head injury. TON is characterized by axon damage in the optic nerve followed by retinal ganglion cell death in th...
Knowledge and occupational practices of beauticians and barbers in the transmission of viral hepatitis: A mixed-methods study in Volta Region of Ghana
Background Hepatitis B and C viral (HBV and HCV) infections are endemic in Ghana. Also, the National Policy on Viral Hepatitis stipulates that there is unreliable data, limited kno...
Tyrosine supplementation is ineffective in facilitating soccer players’ physical and cognitive performance during high-intensity intermittent exercise in hot conditions
Tyrosine has been proposed to potentially provide ergogenic benefits to cognitive and physical performance in physiologically demanding environments. However research into its effectiveness on cogniti...
Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial
Aphasia, a communication disorder caused primarily by left-hemisphere stroke, affects millions of individuals worldwide, with up to 70% experiencing significant reading impairments. These deficits neg...
Quality of life identification by unsupervised cluster analysis: A new approach to modelling the burden of endometriosis
Background Symptoms frequently associated with endometriosis affect quality of life (QoL). Our aim investigated the hypothesis that cluster analysis can be used to identify homogeneous phenotyping sub...
Parallel convolutional neural network and empirical mode decomposition for high accuracy in motor imagery EEG signal classification
In recent years, the utilization of motor imagery (MI) signals derived from electroencephalography (EEG) has shown promising applications in controlling various devices such as wheelchairs, assistive...
Sustainable development through eco-innovation: A focus on small and medium enterprises in Colombia
This study examines the impact of eco-innovation on the economic, social, and environmental performance of small and medium enterprises (SMEs) in Colombia. SMEs are pivotal to Colombia’s economic land...
Edge intelligence for poultry welfare: Utilizing tiny machine learning neural network processors for vocalization analysis
The health of poultry flock is crucial in sustainable farming. Recent advances in machine learning and speech analysis have opened up opportunities for real-time monitoring of the behavior and health...
Perceived stress across population segments characterized by differing stressor profiles—A latent class analysis
Objective We aimed to 1) identify distinct segments within the general population characterized by various combinations of stressors (stressor profiles) and to 2) examine the socio-demographic composi...
Thermal comfort perception among park users in Prague, Central Europe on hot summer days—A comparison of thermal indices
The assessment of human perception of the thermal environment is becoming highly relevant in the context of global climate change and its impact on public health. In this study, we aimed to evaluate t...
Effects of hydrogen on microstructure evolution and mechanical properties of TB8 titanium alloy
The influence of varying hydrogen content on the microstructure, mechanical properties, and fracture behavior of the metastable β titanium alloy TB8 after hydrogen charging has been investigated in th...
The dengue disquisition: A low-cost public housing conundrum in Klang Valley, Malaysia
Dengue remains the most rapidly advancing vector-borne disease in the world, and while the disease burden is predominantly in low-to-middle-income countries, the association with poverty remains in qu...
Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway
Endometriosis is a chronic inflammatory disorder characterized by presence of endometrial tissue outside the uterine cavity. Immunohistochemical analysis (IHC) revealed markedly elevated expression of...
The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? a feasibility, cohort study
Background Induction of labour (IOL) is a common obstetric intervention in the UK, affecting up to 33% of deliveries. IOL aims to achieve a vaginal delivery prior to spontaneous onset of labour to pre...
Correction: Hepatic transcript profiling in beef cattle: Effects of rumen-protected niacin supplementation
Advancing biomonitoring of eDNA studies with the Anaconda R package: Integrating soil and One Health perspectives in the face of evolving traditional agriculture practices
Soil health and One Health are global concerns, necessitating the development of refined indicators for effective monitoring. In response, we present the Anaconda R Package, a novel tool designed to e...
RETRACTED: Synergistic development of intangible cultural heritage and tourism industry: Empirical experiences from Jilin, China
This study focuses on the Jilin region of China, conducting a multidimensional assessment of the current state of the synergistic development between Intangible Cultural Heritage (ICH) and the tourism...
Running trends in Switzerland from 1999 to 2019: An exploratory observational study
Background Several single race events (5 km, 10 km, half-marathon, marathon, ultra-marathon) in different countries and different years have been analyzed in multiple studies, representing the rising...
Stochastic variation in foraging traits within inbred lines of Drosophila
Investigating the causes and consequences of niche partitioning in populations is a major goal in ecology and evolutionary biology. Previous studies have investigated genetic and environmentally induc...
Preventive and curative dental services utilization among children aged 12 years and younger in Tehran, Iran, based on the Andersen behavioral model: A generalized structural equation modeling
World Health Organization invites the nations to progress towards universal health care coverage. This study evaluated preventive and curative dental services utilization among children aged 12 years...
Exploring mental health symptoms in elite athletes during the COVID-19 pandemic: A systematic review and meta-analysis on sex differences
The COVID-19 pandemic significantly affected elite athletes, leading to increased mental health issues such as stress, anxiety, and depression. Sex differences in mental health may exist among athlete...
Long-term excessive salt consumption alters villous and crypt morphology and the protein expression of uroguanylin, TRPV6 and PMCA1b in the rat small intestine
Although long-term high dietary sodium consumption often aggravates hypertension and bone loss, sodium in the intestinal lumen has been known to promote absorption of nutrients and other ions, e.g., g...
Half logistic exponentiated inverse Rayleigh distribution: Properties and application to life time data
This paper presents a novel extension of the exponentiated inverse Rayleigh distribution called the half-logistic exponentiated inverse Rayleigh distribution. This extension improves the flexibility o...