PLoS ONE
Articles in this Issue
Does financial asset allocation term structure affect audit fees? Evidence from China
The financialization of real enterprises presents a dilemma for China’s economic development. This study examines the impact of the financial asset allocation term structure on audit fees using a samp...
Home intravenous diuretic administration for heart failure management: A scoping review
Background Heart failure (HF) significantly impacts healthcare systems due to high rates of hospital bed utilization and readmission rates. Chronic HF often leads to frequent hospitalizations due to r...
Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study
Objective Hypertension, a common chronic disease, often leads to serious complications. While conventional management relies on antihypertensive drugs, which can cause side effects and adherence issue...
Retraction: An Indole Alkaloid from a Tribal Folklore Inhibits Immediate Early Event in HSV-2 Infected Cells with Therapeutic Efficacy in Vaginally Infected Mice
Convolutional neural network (CNN) configuration using a learning automaton model for neonatal brain image segmentation
CNN is considered an efficient tool in brain image segmentation. However, neonatal brain images require specific methods due to their nature and structural differences from adult brain images. Hence,...
Investigation of the trends and associated factors of ovarian cancer in Indonesia: A systematic analysis of the Global Burden of Disease study 1990–2021
Introduction Ovarian cancer is one of the most lethal gynecological cancers. Despite diagnosis and treatment advances, survival rates have not increased over the past 32 years. This study estimated an...
MRI noise and auditory health: Can one hundred scans be linked to hearing loss? The case of the Courtois NeuroMod project
Magnetic resonance imaging (MRI) is one of the most commonly used tools in neuroscience. However, it implies exposure to high noise levels. Exposure to noise can lead to temporary or permanent hearing...
Exploring potential drug targets for SLE through Mendelian randomization and network pharmacology
Background Systemic lupus erythematosus (SLE) is a complex and incurable autoimmune disease, so several drug remission for SLE symptoms have been developed and used at present. However, treatment vari...
Effect of family support and work resources in the relationship of economic constraints and work volition: Evidence from China
Background As the pace of economic development slows, college students are facing an increasingly challenging employment landscape. For instance, the expansion of higher education has led to a swell i...
Development of a rapid antigen-based lateral flow assay for tick-borne spotted fever rickettsioses
Tick-borne spotted fever rickettsioses (SFRs) continue to cause severe illness and death in otherwise-healthy individuals due to lack of a timely and reliable diagnostic laboratory test. We recently i...
Effectiveness of couple-based violence prevention education in reducing intimate partner violence during pregnancy in rural Ethiopia: A cluster randomized controlled trial
Background Pregnancy is often seen as a joyful and fulfilling time for many women. However, a significant number of women in Ethiopia experience intimate partner violence (IPV) during this period. Des...
Effects of antioxidant nutrients on muscle mass, strength and function in COPD patients: A meta-analysis of randomized controlled trials
Aim To comprehensively investigate the effects of antioxidant nutrients on muscle mass, strength and function in chronic obstructive pulmonary disease (COPD) patients. Methods PubMed, Embase, Cochra...
Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial
Background Posttraumatic stress disorder (PTSD) affects 3.9% of the general population. While massed cognitive processing therapy (CPT) has demonstrated efficacy in treating chronic PTSD, a substantia...
Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP)
Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These...
Carbon information disclosure and corporate financial performance—Empirical evidence based on heavily polluting industries in China
Global climate change has become one of the most large-scale, widespread, and far-reaching challenges facing mankind. Against this background, China has proposed a "dual-carbon" target in 2020, which...
Impact of emergency department overcrowding on the occurrence of in-hospital cardiac arrest
We aimed to determine whether emergency department (ED) overcrowding affects the occurrence of in-hospital cardiac arrest (IHCA) requiring resuscitation in the ED. This retrospective study was conduct...
At what cycle threshold level are dogs able to detect SARS-CoV-2 in humans?
Dogs can discriminate between people infected with SARS-CoV-2 from those uninfected, although their results vary depending on the settings in which they are exposed to infected individuals or samples...
Evaluating and upgrading the performance of a bridge network structure with Rayleigh distribution lifetimes
In this work, bridge network model with Rayleigh distribution lifetimes is used. Two main techniques are calculated to upgrade this model: reduction and redundancy techniques. In order to compare the...
Establishing thresholds for swing transparency at the knee during gait to inform exoskeleton design
Knee exoskeletons have been developed to assist, stabilize, or improve human movement or recovery. However, exoskeleton designers must implement transparency (i.e., get out of the way) modes during th...
The impact of health risk communication on self-perceived health and worry of targeted groups: Lessons from the Swedish COVID-19 response
Background The Swedish COVID-19 strategy aimed to protect vulnerable groups through targeted measures, categorizing individuals aged 70 and above as high-risk. This study examines the impact of such g...
Exploration and verification of the therapeutic mechanism of shenfu injection in sepsis-induced myocardial injury
Background Shenfu injection (SFI), derived from a traditional Chinese medicine (TCM) prescription, is an effective drug for the treatment of sepsis-induced myocardial injury (SIMI) with good efficacy,...
Prohibiting Babel—A call for professional remote interpreting services in pre-operation anaesthesia information
Introduction Language barriers within clinical settings pose a threat to patient safety. As a potential impediment to understanding, they hinder the process of obtaining informed c...
Correction: The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial
Automating the amino acid identification in elliptical dichroism spectrometer with Machine Learning
Amino acid identification is crucial across various scientific disciplines, including biochemistry, pharmaceutical research, and medical diagnostics. However, traditional methods such as mass spectrom...
Adolescent reports of subjective socioeconomic status: An adequate alternative to parent-reported objective and subjective socioeconomic status?
Socioeconomic status (SES) is associated with well-being outcomes across studies; however, there is wide variation in its measurement, particularly in adolescence. One key difference in measures of SE...