PLoS ONE
Articles in this Issue
BMI-mediated association between glyphosate exposure and increased risk of atherosclerotic heart disease: A large-scale cross-sectional study
Background Glyphosate, as the main component of glyphosate pesticides, has been shown to have toxic effects on multiple human systems. However, the association between glyphosate and atherosclerotic c...
Computational design of multi-epitope vaccine against Hepatitis C Virus infection using immunoinformatics techniques
Hepatitis C Virus (HCV) is a blood borne pathogen that affects around 200 million individuals worldwide. Immunizations against the Hepatitis C Virus are intended to enhance T-cell responses and have b...
Female genital mutilation among children in Ethiopia: A time-to-event analysis of age at circumcision
Female Genital Mutilation (FGM) has become a global health concern. It is a deeply entrenched harmful practice involving partial or total removal of the external female genitalia for non-medical reaso...
Impacts of continuing education on Primary Health Care professionals—A scoping review protocol
Introduction Continuing Health Education is a strategy that integrates learning into the work process to transform health practices. Primary health care has proved to be a powerful space for consolida...
Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999–2020
Background Ischemic heart disease (IHD) has a significant impact on public health and healthcare expenditures in the United States (US). Methods We used data from the CDC WONDER database from 1999–2...
Randomized clinical trial of ICECaP (Individualized Coordination and Empowerment for Care Partners of Persons with Dementia): Primary mental health and burden outcomes
We examine the efficacy of the Individualized Coordination and Empowerment for Care Partners of Persons with Dementia (ICECaP), an intervention that involves one-on-one individualized support from a d...
The effects of preoperative glenohumeral osteoarthritis on rotator cuff repair: A systematic review and meta-analysis
Purpose This meta-analysis was carried out to evaluate the clinical effectiveness of rotator cuff repair surgery in treating rotator cuff tears in individuals with mild glenohumeral osteoarthritis (GH...
The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis
Purpose To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients. Methods Pertinent studies were searched in PubMed, EMBASE, Web of Science and c...
Combating trade in illegal wood and forest products with machine learning
Trade in wood and forest products spans the global supply chain. Illegal logging and associated trade in forest products present a persistent threat to vulnerable ecosystems and communities. Illegal t...
How is maternal employment associated with infant and young child feeding in Bangladesh? A systematic literature review and meta-analysis
Background In the last three decades, the increasing trend in female employment in Bangladesh has been critically analyzed from a socioeconomic point of view; however, its impact on infant and young c...
Phase angle in bioelectrical impedance analysis for assessing congestion in acute heart failure
Background The phase angle (PhA) in bioelectrical impedance analysis (BIA) reflects the cell membrane integrity or body fluid equilibrium. We examined how the PhA aligns with previously known markers...
Cross- analyzing the opinions and experiences of nurses, physiotherapists, dentists, midwives, and pharmacists with respect to addictive disorder screening in primary care: A qualitative study
Early addiction disorders screening is recommended in primary care. The goal of health system reform is to include allied health professionals in this screening. The appropriation of their new role ha...
Patient adherence, satisfaction and changes in anthropometric parameters with e-health versus in-person monitoring in metabolic bariatric surgery patients: A study protocol for a systematic review and non-inferiority meta-analysis of cohort studies
Background Obesity is a risk factor for cardiovascular diseases and associated with reduced life expectancy metabolic bariatric surgery (MBS) is the treatment indicated when patients are unable to los...
Insulin therapy adherence and its associated factors among diabetic patients in a Ghanaian primary care hospital
Background Diabetes mellitus (DM) is a global health problem. Adherence to intensive insulin therapy is necessary to achieve better glycemic control in types 1 and 2 DM. This study aimed to evaluate t...
Genotype x environment interaction effect on grain yield of cowpea (Vigna unguiculata (L.) Walp) in Deciduous forest and Sudan savanna ecologies of Ghana
Cowpea is deemed as a food security crop due to its ability to produce significant yields under conditions where other staples fail. Its resilience in harsh environments; such as drought, heat and mar...
Metabolic profiling of endophytic fungi acting as antagonists of the banana pathogen Colletotrichum musae
Three endophytic strains, Phomopsis sp., Fusarium proliferatum, and Tinctoporellus epimiltinus, isolated from various plants in the rainforest of the Philippines, were investigated regarding their abi...
Social influence and consensus building: Introducing a q-voter model with weighted influence
We present a model of opinion formation where an individual’s opinion is influenced by interactions with a group of agents. The model introduces a novel bias mechanism that favors one opinion, a featu...
Dynamic emotion intensity estimation from physiological signals facilitating interpretation via appraisal theory
Appraisal models, such as the Scherer’s Component Process Model (CPM), represent an elegant framework for the interpretation of emotion processes, advocating for computational models that capture emot...
Analysis of cervical and breast cancer screening behavior and its influencing factors among urban and rural women in Beijing
Objective To clarify the screening behavior and influencing factors of females with breast cancer and cervical cancer in suburban areas and to provide a scientific basis for the subsequent implementat...
Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells
Single-cell RNA sequencing (scRNA-seq) is a valuable tool for investigating cellular heterogeneity in diseases such as equine asthma (EA). This study evaluates the HIVE™ scRNA-seq method, a pico-well-...
Evaluation of L-carnitine’s protective properties against AlCl3-induced brain, liver, and renal toxicity in rats
A common heavy metal in many facets of daily life is aluminum (AlCl3), which can be found in food, toothpaste, cosmetics, food additives, and numerous pharmaceutical items. The hippocampus, liver, and...
A sector fast encryption algorithm for color images based on one-dimensional composite sinusoidal chaos map
Images are important information carriers in our lives, and images should be secure when transmitted and stored. Image encryption algorithms based on chaos theory emerge in endlessly. Based on previou...
Spatial-temporal evolution of the allometric relationship between urban economic and health resources in the Yangtze River Delta urban agglomeration
The evolution of the spatiotemporal relationship between urban economic growth and health resources within the Yangtze River Delta urban agglomeration provides an important context for understanding t...
Prediction of stunting and its socioeconomic determinants among adolescent girls in Ethiopia using machine learning algorithms
Background Stunting is a vital indicator of chronic undernutrition that reveals a failure to reach linear growth. Investigating growth and nutrition status during adolescence, in addition to infancy a...
Occurrence of virulence genes in multidrug-resistant Escherichia coli isolates from humans, animals, and the environment: One health perspective
Escherichia coli is one of the critical One Health pathogens due to its vast array of virulence and antimicrobial resistance genes. This study used multiplex PCR to determine the occurrence of virulen...