PLoS ONE
Articles in this Issue
Shortcoming of ypStage staging system: Lack of differentiation for preoperative treatment
The eighth edition of the AJCC staging manual initially proposed the ypTNM staging system, which was specifically designed to assess the staging and predict the prognosis of cancer patients undergoing...
Exploring prehabilitation interventions for patients with gynaecological cancer undergoing radiotherapy: A scoping review
Purpose Radiotherapy imposes a significant physiological and psychological burden on gynaecological cancer patients. Prehabilitation is being increasingly used to prepare individuals for cancer treatm...
Correction: The antimicrobial activity of an antiseptic soap against Candida Albicans and Streptococcus Mutans single and dual-species biofilms on denture base and reline acrylic resins
Research on the Polishing Process of Wolter-I Type Grazing Incidence Mirrors
As the demand for solar X-ray observation devices continues to rise, the Wolter-I type grazing incidence mirror has emerged as a critical component in these instruments, particularly for high-precisio...
Indications and endoscopic findings of upper gastrointestinal diseases in Africa: A systematic review & meta-analysis
Background Upper gastrointestinal endoscopy (UGIE) plays a crucial role in diagnosis of gastrointestinal pathology. Therefore, this systematic review and meta-analysis aimed to assess the indications...
Extant life detection using label-free video microscopy in analog aquatic environments
The ability of microbial active motion, morphology, and optical properties to serve as biosignatures was investigated by in situ video microscopy in a wide range of extreme field sites where such imag...
Performance of pelican optimizer for energy losses minimization via optimal photovoltaic systems in distribution feeders
In distribution grids, excessive energy losses not only increase operational costs but also contribute to a larger environmental footprint due to inefficient resource utilization. Ensuring optimal pla...
Microfluidic isolation and release of live disseminated breast tumor cells in bone marrow
Breast cancer represents a significant therapeutic challenge due to its aggressive nature and resistance to treatment. A major cause of treatment failure in breast cancer is the presence of rare, low-...
A methodological framework for deriving the German food-based dietary guidelines 2024: Food groups, nutrient goals, and objective functions
Background For a growing number of food-based dietary guidelines (FBDGs), diet optimization is the tool of choice to account for the complex demands of healthy and sustainable diet...
Oral fluid supplementation for the prevention of post-dural puncture headache: A noninferiority randomized controlled trial
Aim(s) To investigate the impact of the absence of specific advice for oral fluid intake, compared to supplementation water intake on the occurrence of post-dural puncture headache. Design A prospec...
Relationship between sleep variables and interoceptive awareness in daytime workers
Interoception refers to the sensation of internal and physiological bodily states, such as heart rate, and contributes to the maintenance of bodily internal homeostasis. Some studies showed that inter...
The impact of canine-assisted intervention on stress reduction among university students in Thailand
Stress negatively impacts university students, leading to adverse outcomes. While canine-assisted intervention (CAI) has been shown to reduce self-reported stress, no studies have investigated stress...
The impact of work-family conflict on job burnout among community social workers in China
In China, for community social workers, work-family conflict has become a common phenomenon that may harm their well-being. Based on the analysis of a survey of community social workers in four cities...
Deciphering the structural consequences of R83 and R152 methylation on DNA polymerase β using molecular modeling
DNA polymerase β, a member of the X-family of DNA polymerases, undergoes complex regulations both in vitro and in vivo through various posttranslational modifications, including phosphorylation and me...
Measuring real-time violence exposure and its impact on intimate partner violence perpetration among adolescents
Background Intimate partner violence (IPV) has dire health consequences. To intervene, it is critical we first understand why young men perpetrate IPV. One theory is that men who experience violence a...
Correction: Neuroprotective effect of Kaempferol Glycosides against brain injury and Neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke
Impact of a three-week full leg cast immobilization on infant crawling kinetics and spatiotemporal parameters
Despite its importance in the development of mobility in infants, there is a general lack of quantified data on infant crawling, and a specific lack of understanding of crawling kinetics, which includ...
Study on the failure of oil-contaminated wheel-rail conditions
The phenomenon of adhesion improvement during wheel-rail sliding has been experimentally verified under water conditions. However, the academic community is in agreement that, for oil that is also flu...
Preschool children of parents who screen positive for mental health problems have an increased risk of subsequent mental disorders: Findings from a longitudinal follow-up study in Sweden
Research has shown associations between parental and child mental health problems. However, there is a paucity of Swedish studies on this topic. Investigating this link in a Swedish context could info...
Gamma activity concentration from building materials: Estimation of gamma absorption and indoor radon concentration in Katsina State, Nigeria
In this research, nineteen (19) samples were collected and analyzed with the following objectives: to evaluate the activity concentration of radionuclides, assess gamma absorption, determine indoor ra...
Effects of mental fatigue on isometric mid-thigh pull performance and muscle activities
This study investigated the effects of mental fatigue on rate of force development (RFD) and peak force during an isometric mid-thigh pull (IMTP), as well as its impact on muscle activation measured b...
The impacts of product characteristics and regulatory environment on smokers’ preferences for tobacco and alcohol: Evidence from a volumetric choice experiment
Objective Concurrent use of alcohol and cigarettes is well-documented in the literature. However, it is unclear how e-cigarette regulations in a growing number of localities impact the use of tobacco...
Remote work and long-term sickness absence due to mental disorder trends among Japanese workers pre/post COVID-19
Aims The aim of this study was to ascertain whether there has been an increase in the number of workers with long-term sickness absence due to mental disorders (LTSA-MD) and determine the impact of r...
Conditioned medium of engineering macrophages combined with soluble microneedles promote diabetic wound healing
Diabetic wounds have a profound effect on both the physical and psychological health of patients, highlighting the urgent necessity for novel treatment strategies and materials. Macrophages are vital...
cAmbly: A non-toxic cell-penetrating peptide derived from Amblyomin-X with targeted delivery to mitochondrial and cytoplasmic proteins
The effective delivery of drugs remains a major challenge in the development of new therapeutic molecules. Several strategies have been employed to address this issue, with cell-penetrating peptides (...