PLoS ONE
Articles in this Issue
Unveiling the social and environmental benefits of digital transformation in corporations
In the context of the “dual-carbon” goal and the digital economy, exploring the impact of digital transformation on enterprises’ social and environmental responsibility is a key issue for achieving su...
Genome-wide SNPs reveal novel genetic relationships among Atlantic cod (Gadus morhua) from the south coast of Newfoundland, Canada (subdivision 3Ps), Northern cod stock complex, and Gulf of St Lawrence
The south coast of Newfoundland, Canada (Northwest Atlantic Fisheries Organization (NAFO) Subdivision 3Ps) is known to be a mixing zone for Atlantic cod (Gadus morhua). Tagging and genetic studies hav...
Optimization design and experiment of key components of mountain pendulum-lever cam type hole seeders based on DEM-MBD coupling simulation
In response to issues such as high miss-seeding rates and uneven seed grain distribution during the operation of the pendulum-lever camshaft hole seeders under the compound planting mode of corn and s...
Factors influencing ankle alignment changes following medial unicompartmental knee arthroplasty: Preoperative knee and ankle deformities and extent of knee alignment correction
Introduction The impact of medial unicompartmental knee arthroplasty (MUKA) on ankle alignment is not well-studied. This study aims to investigate the changes in ankle alignment following MUKA and ide...
“You do need each member of the team to bring that next piece of the puzzle”: Allied health professionals’ experience of interprofessional complex care in hospital settings
This study explores the experiences of allied health professionals who work in interprofessional hospital complex care teams. The aim of the study was to identify factors influential to meaningful cli...
Disparities in use of physical restraint and chemical sedation in the emergency department by patient housing status
Background A growing body of research has found there to be disproportionate physical restraint and chemical sedation use for historically marginalized populations in the emergency department (ED). Th...
Species distribution of Cannabis sativa: Past, present and future
Cannabis sativa L. is an annual flowering herb of Eurasian origin that has long been associated with humans. Domesticated independently at multiple locations at different times for different purposes...
A multidisciplinary protocol for reducing excessive and maintaining a healthy body weight in the personalized management of chronic diseases in children and adults
Despite regularly used treatment asthma in both children and adults is not fully controlled. This is more prominent in certain disease subtypes, such as obese asthma. The vast complexity of asthma phe...
Oral pain and comorbidities in an edentulous older population: A k-prototypes cluster analysis
Non-odontogenic oral pain is prevalent among the older people and significantly impacts their quality of life. Non-odontogenic oral pain is usually persistent and accompanied by comorbidities such as...
Structured follow-up pathway to address unmet needs after transient ischaemic attack and minor stroke (SUPPORT TIA): Feasibility study and process evaluation
Background Care following transient ischaemic attack (TIA) and minor stroke is variable and often leaves patients feeling abandoned and uncertain. We developed a theoretically-informed, multifaceted i...
Pooled prevalence and associated factors of ECG abnormality among type 2 diabetic patients in the last ten years: Systematic review and meta-analysis
Background Type 2 diabetes mellitus is a global epidemic affecting millions of individuals worldwide. It is considered a chronic metabolic disorder of impaired glucose homeostasis, associated with va...
Examining dose-response of an outdoor walk group program in the Getting Older Adults Outdoors (GO-OUT) trial
Objective The Getting Older Adults Outdoors (GO-OUT) randomized trial showed that a 10-week outdoor walk group (OWG) program was not superior to 10 weekly phone reminders in increasing physical and me...
Evaluating the protective effects of the Toll-like receptor (TLR) 21 ligand, CpG ODN, against necrotic enteritis in broiler chickens
Necrotic enteritis (NE), caused by Clostridium perfringens (C. perfringens), presents a challenge to the global broiler industry. Evidence suggests that Toll-like receptor (TLR) ligands can enhance th...
Ecological footprints, global sustainability, and the roles of natural resources, financial development, and economic growth
The prevailing ecological deficit is devastating the ecosystem which is leading toward the unsustainability by endangering the livings on earth. The important drivers of this environment degradation a...
Revolutionizing Molecular cloning: Introducing FastCloneAssist, a Streamlined Python tool for optimizing primer design in restriction & ligation-independent PCR cloning
FastCloning, a paradigm shift in PCR cloning, has streamlined the process by eliminating laborious, multi-step traditional methods. This innovative technique, pioneered by Li et al. (2011), utilizes o...
The impact of carbon information disclosure on corporate green technology innovation in the context of “dual carbon”—— Based on data from heavily polluting industries
In the current global response to climate change, the “dual carbon” goal has become a common development goal for all countries. In the context of “dual carbon”, China’s heavily polluting enterprises,...
Functional role for Taz during hindbrain ventricle morphogenesis
The brain ventricle system, composed of the ventricular cavities and the cerebral spinal fluid within, performs critical functions including circulation of nutrients, removal of wastes, and cushioning...
Digital PCR characterizes epithelial cell populations in murine duodenal organoids
Three-dimensional cultures are powerful tools to recapitulate animal and human tissues. Under the influence of specific growth factors, adult stem cells differentiate and organize into 3D cultures nam...
Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction
Hypertension in the elderly can seriously lead to cerebral microvascular damage and promote the development of vascular cognitive impairment. While endothelial function is crucial in cerebral microvas...
Modelling Temperature-dependent Schistosomiasis Dynamics for Single and Co-infections with S. mansoni and S. haematobium
Schistosomiasis, a prevalent public health issue specifically in sub-Saharan Africa, is primarily attributed to Schistosoma haematobium and Schistosoma mansoni, often occurring concurrently. These sch...
Revisiting the physical limits to economic growth, with a focus on the waste heat limit
Whether there are imminent physical limits to economic growth has been the focus of a long-standing debate, often (but not exclusively) pitting natural scientists against economists. One side of the d...
Determining cost-saving risk thresholds for statin use
Background The German government has recently drafted a bill proposing a reduction in the prescription threshold for statin use. This study aims to determine the cost-saving risk t...
Spatio-temporal evolution of habitat quality and its influencing factors in karst areas based on the InVEST model
The Critical Karst Zone provides rich natural resources and is an important habitat for the survival and development of the world’s human population. Meanwhile, urbanization processes have disrupted t...