PLoS ONE
Articles in this Issue
Optimizing skin cancer screening with convolutional neural networks in smart healthcare systems
Skin cancer is among the most prevalent types of malignancy all over the global and is strongly associated with the patient’s prognosis and the accuracy of the initial diagnosis. Clinical examination...
PGAP3 is expressed at increased levels in asthmatic ASM and is associated with increased ASM proliferation, contractility and expression of GATA3 and ALOX5
Post-GPI Attachment to Proteins phospholipase 3 (PGAP3) is a glycosylphosphatidylinositol (GPI) anchor-remodeling gene found on chromosome 17q12-21, which is a locus highly linked to asthma. Genetic a...
A Comparison of neoadjuvant chemotherapy and concurrent chemoradiotherapy for for FIGO 2018 stage IB3/IIA2 Cervical squamous cell carcinoma: Long-term efficacy and safety in a resource-limited setting
Purpose The purpose of this research was to evaluate the effectiveness and safety of neoadjuvant chemotherapy plus radical surgery (NCRS) and concurrent chemoradiotherapy (CCRT) based on three-dimens...
The validation of the CTS-6 Evaluation Tool for diagnosing carpal tunnel syndrome (CTS) in Thai wheelchair users
Objective The CTS-6 Evaluation Tool is a clinical diagnostic tool for carpal tunnel syndrome. It was originally developed using data from non-disabled individuals and has never been validated in diff...
Correction: Impact of genetic background as a risk factor for atherosclerotic cardiovascular disease: A protocol for a nationwide genetic case-control (CV-GENES) study in Brazil
Correction: Engineered red Opto-mGluR6 Opsins, a red-shifted optogenetic excitation tool, an in vitro study
Effect of emotional regulation on performance of shooters during competition: An ecological momentary assessment study
Objective The purpose of this study was to examine the effect of emotion regulation on shooting performance in shooting athletes. Method Ecological momentary assessment was used to track and examine...
Analysis of the incidence and influencing factors of high-risk foot in elderly patients with type 2 diabetes in a community in Beijing
Background Diabetic foot is one of the important causes of disability and death in diabetic patients, and effective measures can reduce or prevent the occurrence of diabetic foot, among which, the sc...
Nesting of groups: Links among personal magnetism, community trust, inequality perception and depression
Background In the context of China’s rapid transition from a collectivist work-unit system to a more individualized, community-oriented society, this study investigates the relationship between person...
Responses of soil health to seasonal change under different land cover types in a sub-tropical preserve ecosystem
In subtropical preserve ecosystems, natural factors combined with anthropogenic activities have led to significant seasonal changes, including distinct dry and rainy seasons. These changes can potenti...
Analytic solutions of variance swaps for Heston models with stochastic long-run mean of variance and jumps
This paper presents the pricing formulas for variance swaps within the Heston model that incorporates jumps and a stochastic long-term mean for the underlying asset. By leveraging the Feynman-Kac theo...
Current status of Tele-speech language therapy by type and support for patients with post-stroke aphasia: A scoping review
Purpose The purpose of this study was to classify and analyze trends in the assessment and training methods used in telepractice speech-language therapy (Tele-SLT) for people with aphasia (PWA), acco...
Neonatal febrile seizures: Dimethyl itaconate’s role in behavioral recovery and glutathione enzyme modulation in adult rats
Febrile seizures are common in children and can lead to neurological deficits like motor impairments, memory problems, and cognitive decline. Research on dimethyl itaconate aims to mitigate these effe...
Does hydroxychloroquine reduce the risk of infection in patients with systemic lupus erythematosus? a systematic review and meta-analysis
Objectives This study aimed to investigate the anti-infective utility of hydroxychloroquine in patients with systemic lupus erythematosus (SLE) by analyzing published case-control and cohort studies....
Effect of the online module on leadership in knowledge acquisition among nursing students: A randomized controlled study protocol
Leadership is an essential skill for success in nursing practice, influencing the nursing team’s organization, the quality of health services and decision-making in complex situations. The COVID-19 pa...
Correction: An orchestra of machine learning methods reveals landmarks in single-cell data exemplified with aging fibroblasts
Evolutionary history of the DNA repair protein, Ku, in eukaryotes and prokaryotes
Ku is essential in non-homologous end-joining (NHEJ) across prokaryotes and eukaryotes, primarily in double-stranded breaks (DSBs) repair. It often presents as a multi-domain protein in eukaryotes, un...
Low Hepatitis B vaccination rates among medical students in South Asia: A systematic review and meta-analysis
Background and aims Current and future healthcare professionals, such as medical students, are at risk of contracting Hepatitis B virus infection. Vaccination against Hepatitis B is an effective mean...
Adoption of sustainable fuels and renewable energy in logistics: Examining the role of stakeholder theory in supply chain strategy
In contemporary society, sustainability is a key issue that borders on overall human existence, and it has been rigorously argued that extensive efforts are needed to ensure the survival of the human...
The effect of antibiotic prescription in non-critically ill hospitalized patients with COVID-19: A Japanese inpatient database study
Background Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic. Bacterial coinfections with COVID-19 occur in 3.5% of COVID-19 cases, with a higher incidence in severe cases. Although a...
Tislelizumab plus chemotherapy versus chemotherapy as first-line treatment for extensive-stage small cell lung cancer: A cost-effectiveness analysis
Objective This study aims to conduct a cost-effectiveness analysis of tislelizumab in combination with platinum and etoposide compared to the standard treatment of etoposide and platinum as first-line...
Partnering with periodontal patients and care providers to establish research priorities for patient engagement in specialized periodontal care: A study protocol
Introduction Periodontitis is highly prevalent and disproportionately affects vulnerable populations, including older adults, racial and ethnic minorities, and low-income individuals. While periodonta...
Incidence of electrocardiographic and electrolyte changes in acute oleander poisoning in humans: A systematic review and meta-analysis protocol
Yellow oleander (Cascabela thevetia, previously known as Thevetia peruviana) & Common oleander (Nerium oleander) contain a wide range of cardiac glycosides and their toxicity is similar to digoxin...
Acceptability and feasibility of HIV self-testing integration into publicly-funded HIV prevention services: Perspectives from HIV testing agency staff that provide HIV testing services to sexual and gender minority youth in Philadelphia County
Background Increasing HIV testing among priority populations is a primary strategy of the Ending the HIV Epidemic initiative. In October 2019, the Philadelphia Department of Public Health (PDPH) estab...
Dosing patterns and dose effects of sacubitril/valsartan: A claims-based retrospective cohort study
Purpose The goals of this retrospective cohort analysis were to determine real-world dose and titration patterns of sacubitril/valsartan (SAC/VAL), a heart failure medication, and examine whether dos...