PLoS ONE
Articles in this Issue
Correction: Creating an arena for being in the same boat: A qualitative study of course instructors’ experiences with the Coping with Depression course’s group setting
SAT1 promotes the progression of OA by regulating TRIM33-mediated p53 acetylation to enhance ferroptosis
Background Ferroptosis is a nonapoptotic form of cell death characterized by lipid peroxidation and intracellular iron accumulation. OA is a prevalent joint disease, and as OA progresses, inflammation...
BLSAM-TIP: Improved and robust identification of tyrosinase inhibitory peptides by integrating bidirectional LSTM with self-attention mechanism
Tyrosinase plays a central role in melanin biosynthesis, and its dysregulation has been implicated in the pathogenesis of various pigmentation disorders. The precise identification of tyrosinase inhib...
The spatial distribution of salt tolerant bacteria and other soil parameters under different agricultural systems of the Indian Sundarbans
Salinization is a major contributor to soil degradation and poses a substantial threat to agriculture. In India, approximately 6.73 million hectares of lands are affected by salinity, with the Indian...
Octopus track chemosensory plumes to find food
Chemosensory plume-guided navigation, tracking a chemical plume to its source, is a primordial behavior used by many animals to search beyond the visual range. Here we report the first laboratory obse...
An in vitro tumor recurrence model based on platinum-resistant colon cancer cells as a research tool for studying cancer cell dormancy
Modeling cancer recurrence and associated conditions such as cancer cell dormancy remains a significant challenge in cancer research. We developed a novel in vitro model based on platinum-resistant tu...
Public perceptions and support for introduced microbes to combat hospital-acquired infections and antimicrobial resistance
Hospital-acquired infections and antimicrobial resistance (AMR) remain major global health threats, prompting interest in microbiome-based interventions that introduce beneficial microbes or genetic i...
The association between mental health and cognitive ability: Evidence from the Understanding Society survey
Background The relationship between poor mental health and cognitive impairments in older age is well-established. Social engagement also influences cognitive ability. However, current research has no...
Rock physics-based approach to assess the effectiveness of cement-based backfill materials in coal mining
Coal production for energy generation results in series of ecological and environmental degradation in mining areas. backfilling of goafs is considered as a suitable method for the mitigation of afore...
Machine learning-based forecasting of air quality index under long-term environmental patterns: A comparative approach with XGBoost, LightGBM, and SVM
Air pollution is a global problem that threatens environmental sustainability and severely affects public health. Monitoring air quality and predicting future pollution levels are critical for creatin...
Structural and functional analysis of Escherichia coli membrane disruption by Ib-M peptides
Antimicrobial resistance represents a critical global public health challenge, leading to increased mortality and morbidity due to the ineffectiveness of current antibiotics against bacterial infectio...
Impact of COVID-19 on English Football Premier League: Analyzing rankings and home advantage using extended Bradley-Terry models
COVID-19 significantly impacted sports tournaments, particularly soccer. During the pandemic, restrictions on spectators and frequent team composition changes due to outbreaks, providing a unique oppo...
Costs of mental health care resource use in people with obesity: A systematic review
Introduction Obesity is a complex condition with significant economic implications. Healthcare costs associated with obesity are spread across all categories of health services, including mental healt...
Optimization of machine tool processing scheduling based on differential evolution algorithm
Machine tool processing scheduling plays a pivotal role in modern manufacturing systems, significantly influencing production efficiency, resource utilization, and timely delivery. Due to its combinat...
Effect of canal blocking on biodiversity of degraded peatlands: Insight from West Kalimantan
Large-scale disturbance in peatland areas causes many wildlife species to suffer due to limited resources or habitat loss. Following the high attention to peatlands, some restoration efforts, such as...
Effects of virtual reality simulation on medical students’ emotional and subjective experience compared to high-fidelity simulation in pediatrics clerkship
This study aimed to explore the educational impact of virtual reality (VR) simulation compared to high-fidelity (HF) simulation. Recently, VR simulation has been integrated into medical education, off...
Correction: Conformity and tradition are more important than environmental values in constraining resource overharvest
Correction: The social amplification and attenuation of COVID-19 risk perception shaping mask wearing behavior: A longitudinal twitter analysis
A pipeline for rapid, high-throughput imaging and quantitative analysis of human intestinal organoids
Human intestinal organoids (HIOs) are a model system for studying human intestinal epithelium. Utilizing HIOs for high-throughput studies remains inefficient, as analyzing their cellular composition a...
Captivity-driven microbiota reshaping: A cross-species analysis of divergent patterns in the gut microbiota of giant pandas (Ailuropoda melanoleuca), red pandas (Ailurus fulgens), and Asiatic black bears (Ursus thibetanus)
The relative influence of diet, host phylogeny, and environment on animal gut microbiota remains unresolved, particularly for endangered ursids lacking quantitative data. Here, we systematically evalu...
Multidimensional health patterns and labor market participation among older workers: Evidence from a European six-year follow-up study
Health is a multidimensional concept and consists of different dimensions such as mental and physical health. In this study, we built on this conception of health by investigating the effects of multi...
Dipsticks and point-of-care Microscopy in Urinary Tract Infections in primary care: Results of the MicUTI pilot cluster randomised controlled trial
Objectives To evaluate the feasibility of a novel point-of-care test (POCT) management strategy including phase contrast microscopy for bacteriuria and urinary dipsticks for erythrocytes to guide anti...
Correction: How belief in a just world shapes academic engagement among Chinese college art majors: A cross-level moderated mediation model
Disclosing HIV status to sexual partner: Findings from a People Living with HIV Stigma Index 2.0 study in the country Georgia
Background HIV status disclosure to sexual partner plays an important role in fostering transparency and reducing stigma, yet it remains a complex issue influenced by various sociodemographic, psychos...
Microbiome characterization of a pre-Hispanic man from Zimapán, Mexico: Insights into ancient gut microbial communities
The research of microbiome derived from mummified human remains, coprolites and paleofeces has gained significant interest over several decades, aiming to elucidate the evolution of microbial interact...