PLoS ONE
Articles in this Issue
Numerical testing method and mechanical property evaluation of large particle size asphalt mixture
The large particle size asphalt mixture with nominal maximum aggregate size 53 mm(LSAM-50) has good technical and economic performance and will become an effective technical way to build a full-thick...
N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade
The cardiopulmonary nematode Angiostrongylus vasorum can cause severe disease in dogs, including coagulopathies manifesting with bleeding. We analysed A. vasorum excretory/secretory protein (ESP)-trea...
Warming accelerated phosphorus release from the sediment of Lake Chaohu during the decomposition of algal residues: A simulative study
Algal decomposition plays an important role in affecting phosphorus (P) release from sediments in eutrophic lakes under global warming. Yet how rising air temperature affect endogenous P release from...
Are adverse childhood experiences scores associated with heroism or villainy? A quantitative observational study of Marvel and DC Cinematic Universe characters
Many superhero and villain stories include trauma, which could influence how the public perceives the impact of trauma in their own lives. Our aim was to assess whether total Adverse Childhood Experie...
3D fluorescence staining and confocal imaging of low amount of intestinal organoids (enteroids): Protocol accessible to all
The emerging field of 3D organ modeling encounters several imaging issues in particular related to antigen retrieval and sample loss during staining processes. Due to their compact shape, several anti...
Altered microbiome and metabolome profiling in fearful companion dogs: An exploratory study
Behavioral dysfunctions in dogs represent one of the main social concerns, since they can endanger animals and human-dog relationship. Together with the trigger stimulus (human, animal, place, scent,...
Modelling of online shopping behavior in the Czech online environment
The online environment has its own specifics, which shape the specific behavior of all market subjects, both customers and companies that trade electronically. The aim of the paper is to create, quant...
Nasal microbiota predictors for methicillin resistant Staphylococcus colonization in critically ill children
Background Surveillance cultures to identify patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) is recommended at pediatric intensive care unit (PICU) admission but doesn’t cap...
Correction: How long can tardigrades survive in the anhydrobiotic state? A search for tardigrade anhydrobiosis patterns
Study of PEG-rhG-CSF for the prevention of neutropenia in concurrent chemoradiotherapy for nasopharyngeal carcinoma
Background To study the efficacy and safety of Polyethylene glycolated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) in the prevention of neutropenia during concurrent chemorad...
Determination of optimal gamma radiation dose for mutation breeding in ’Sabz’ fig (Ficus carica L.) cuttings based on radiosensitivity and phenotypic changes
The dried fig cv. Sabz of Iran, distinguishes out among the several fig cultivars for its unique characteristics and excellent properties. The aims to this study were 1) Carefully monitoring the resul...
Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase
Geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme in protein prenylation, plays a critical role in cellular signal transduction and is a promising target for cancer therapy. However, the enz...
Gene expression analysis reveals mir-29 as a linker regulatory molecule among rheumatoid arthritis, inflammatory bowel disease, and dementia: Insights from systems biology approach
Background Rheumatoid arthritis (RA) is a degenerative autoimmune disease, often managed through symptomatic treatment. The co-occurrence of the reported extra-articular comorbidities such as inflamma...
Aligned membranes regulate wound healing via MMP12 secreted by macrophages
Aligned electrospinning membranes (Align) have demonstrated the potential to enhance wound healing by establishing a regenerative microenvironment surrounding the wound; However, the precise mechanism...
Prevalence and features of allergic bronchopulmonary aspergillosis, United States, 2016–2022
The epidemiology of allergic bronchopulmonary aspergillosis (ABPA) in the United States is not well-described. To estimate national ABPA prevalence among patients with asthma or cystic fibrosis, chara...
Assessing changing baleen whale distributions and reported incidents relative to vessel activity in the Northwest Atlantic
Baleen whales are among the largest marine megafauna, and while mostly well-protected from direct exploitation, they are increasingly affected by vessel traffic, interactions with fisheries, and clima...
Improving early prediction of crop yield in Spanish olive groves using satellite imagery and machine learning
In the production sector, the usefulness of predictive systems as a tool for management and decision-making is well known. In the agricultural sector, a correct economic balance of the farm depends on...
Analyzing robust dividend payout policy with dynamic panel regression: Application of speed of adjustment to half-life
This study aims to observe the effects of financial metrics, free float shareholders, GDP growth and firm age on dividend payout policy in both the short- and long-term scenarios. The study introduces...
The value co-creation mechanism of Public Cultural Services ecosystem in China based on "public value" theory
The establishment of China’s public cultural service system has been explored for nearly two decades, but there is still a significant gap in achieving the goal of equalising and eliminating differenc...
MESS to live with schizophrenic parental history: A systematic review of developmental checkpoints
Parental history of schizophrenia, a complex and multifaceted psychological disorder, is recognized as a well-established risk factor in the development of the disorder among offspring. However, the d...
Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products
Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial regulators of cell cycle progression and represent important therapeutic targets in breast cancer. This study employs a comprehensive computationa...
State of the art modelling for the Black Sea ecosystem to support European policies
The Black Sea is affected by numerous anthropogenic pressures, such as eutrophication and pollution through coastal and river discharges, fisheries overexploitation, species invasions, and the impacts...
Maternal characteristics and their relation to early mother-child interaction and cognitive development in toddlers
Early mother-infant interaction is believed to have a significant impact on the social, cognitive, and emotional development of children. These interactions are not only influenced by child and contex...
Binaural speech intelligibility for combinations of noise, reverberation, and hearing-aid signal processing
Binaural speech intelligibility in rooms is a complex process that is affected by many factors including room acoustics, hearing loss, and hearing aid (HA) signal processing. Intelligibility is evalua...
A cross-sectional network analysis of successful aging in a resilience-based framework
Aging inevitably gives rise to many challenges and transitions that can greatly impact our (mental) well-being and quality of life if these are not controlled adequately. Hence, the key to successful...