PLoS ONE
Articles in this Issue
The impact of specialised gastroenterology services for pelvic radiation disease (PRD): Results from the prospective multi-centre EAGLE study
To undertake a mixed-methodology implementation study to improve the well-being of men with gastrointestinal late effects following radical radiotherapy for prostate cancer. All men completed a valida...
Covariate-adjusted construction of gene regulatory networks using a combination of generalized linear model and penalized maximum likelihood
Many machine learning techniques have been used to construct gene regulatory networks (GRNs) through precision matrix that considers conditional independence among genes, and finally produces sparse v...
Low levels of Plasmodium falciparum parasitaemia among patients receiving antiretroviral therapy at the treatment centre of the Regional Hospital Bamenda, Northwest Cameroon
Background Malaria and HIV are leading causes of death in Africa, including Cameroon. Antiretroviral therapy (ART) is expected to boost immunity and reduce vulnerability to opportunistic infections. R...
Joint trajectories of physical activity, health, and income before and after statutory retirement: A 22-year follow-up
Background Health behaviors, health, and income change during aging. However, no previous studies have examined, how they develop together over the transition to statutory retirement. We aimed to exam...
Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu
Background Smoking is a major public health concern in Tamil Nadu, as it is in many parts of the world. It is a leading cause of preventable diseases and deaths, with a significant economic burden on...
The effect of physical exercise and cognition-orientated interventions on post-stroke cognitive function: Protocol for an overview of reviews
Background Strokes are becoming more common, and with improving survival rates, the prevalence of stroke survivors has increased. Almost half of chronic stroke survivors are cognitively impaired, and...
Retraction: Transcultural validation of the “revised sport motivation scale” (SMS‐II) in Arabic language: Exploratory study on motivation in sport for a sample of Tunisian Athletes
Nurses’ knowledge and its determinants in surgical site infection prevention: A comprehensive systematic review and meta-analysis
Objective The objective of this systematic review and meta-analysis is to assess and synthesize the global evidence on the level of nurses’ knowledge and its determinants regarding the prevention of s...
Arsenic efflux and bioremediation potential of Klebsiella oxytoca via the arsB gene
Arsenic-resistant Klebsiella oxytoca strain AT-02 was isolated from the ground water of the Multan region of Pakistan. The strain displayed high arsenite and arsenate resistance as minimal inhibitory...
Accuracy of latest large language models in answering multiple choice questions in dentistry: A comparative study
Objectives This study aims to evaluate the performance of the latest large language models (LLMs) in answering dental multiple choice questions (MCQs), including both text-based and image-based questi...
Effects of intrathecal administration of sodium nitroprusside and nicardipine on cerebral pial microcirculation, cortical tissue oxygenation, and electrocortical activity in the early post-resuscitation period in a porcine cardiac arrest model
Recent studies suggested intrathecal vasodilator administration as a therapy to mitigate post-ischemic cerebral hypoperfusion following cardiac arrest. We examined the effects of two commonly used int...
Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis
Background Cold-water immersion (CWI) has gained popularity as a health and wellbeing intervention among the general population. Objective This systematic review and meta-analysis aimed to evaluate...
Measurement of population agglomeration, dynamic change characteristics, and motivations in metropolitan agglomerations—A case study of the Xi’an metropolitan area
This article compares the population agglomeration characteristics of the Xi’an metropolitan area in western China with those of metropolitan areas in other regions officially approved by the Chinese...
Relationships between multivitamins, blood biochemistry markers, and BMC and BMD based on RF: A cross-sectional and population-based study of NHANES, 2017–2018
Background Previous studies have separately suggested a possible association between the vitamin exposure, blood biochemical indicators, and bone density. Ou...
Correction: Towards an affect intensity regulation hypothesis: Systematic review and meta-analyses of the relationship between affective states and alcohol consumption
Anxiety among cancer patients: A cross-sectional study at The University of Gondar comprehensive specialized hospital
Introduction Anxiety is a prevalent psychological issue among cancer patients, significantly affecting their quality of life and potentially influencing treatment outcomes. This study aims to investig...
Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder
Background Bipolar Disorder (BD) is a complex disease. It is heterogeneous, both at the phenotypic and genetic level, although the extent and impact of this heterogeneity is not fully understood. One...
The impact of anticoagulant-related bleeding on quality of life: Development of a novel measure based on perspectives from older adults
Background Venous thromboembolism (VTE) and atrial fibrillation (AF) disproportionately affect older adults, who are at increased risk of bleeding from treatment with anticoagulant therapy. The impact...
Venous leg ulcer healing as a determinant of quality of life in patients treated with unna boot: A quasi-experimental study
Our objective was to assess the effect of Venous Leg Ulcer (VLU) healing on Quality of Life (QoL) in patients undergoing compression therapy. This non-randomized, quasi-experimental, and observational...
Mouthguard use, hygiene, and maintenance practices among combat and team sports athletes: A comparative study
This study aimed to investigate the attitudes of combat and team sports athletes towards the use, storage, and hygiene conditions of mouthguards, with the goal of understanding disparities in usage an...
The efficacy of novel biomarkers for the early detection and management of acute kidney injury: A systematic review
Acute kidney injury (AKI) is a frequent clinical complication lacking early diagnostic tests and effective treatments. Novel biomarkers have shown promise for enabling earlier detection, risk stratifi...
“I sometimes feel like I can’t win!”: An exploratory mixed-methods study of women’s body image and experiences of exercising in gym settings
Despite an increase in gym memberships, women are less active than men and little is known about the barriers women face when navigating gym spaces. This study explored women’s body image and experien...
Taming the transplant troll: Exploring racial and ethnic disparities in cytomegalovirus infection among kidney transplant patients
Background Cytomegalovirus (CMV) infection poses a significant risk to kidney transplant recipients. This study investigated CMV disease incidence, outcomes, and management challenges in racial and et...
Beyond the spotlight: Unveiling the gender bias curtain in movie reviews
Historically, the film industry has been male-dominated both in front of and behind the camera, resulting in a longstanding gender imbalance in storytelling and representation. This legacy of male-cen...
Exploring the relationship between established HIV risk factors and depressive symptoms amongst young women without HIV in two sites in South Africa
Purpose Adolescent girls are at high risk for depression and human immunodeficiency virus (HIV) acquisition. Poor mental health can increase vulnerability to risky sexual behaviours. Therefore, this s...